Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Christian L. Barrett"'
Autor:
Christopher DeBoever, Emanuela M Ghia, Peter J Shepard, Laura Rassenti, Christian L Barrett, Kristen Jepsen, Catriona H M Jamieson, Dennis Carson, Thomas J Kipps, Kelly A Frazer
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 3, p e1004105 (2015)
Mutations in the splicing factor SF3B1 are found in several cancer types and have been associated with various splicing defects. Using transcriptome sequencing data from chronic lymphocytic leukemia, breast cancer and uveal melanoma tumor samples, we
Externí odkaz:
https://doaj.org/article/f0be6649c9804c43879efa31088d25ef
Autor:
Christian L Barrett, Richard B Schwab, HyunChul Jung, Brian Crain, Daniel J Goff, Catriona H M Jamieson, Patricia A Thistlethwaite, Olivier Harismendy, Dennis A Carson, Kelly A Frazer
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58714 (2013)
The only therapeutic options that exist for squamous cell lung carcinoma (SCC) are standard radiation and cytotoxic chemotherapy. Cancer stem cells (CSCs) are hypothesized to account for therapeutic resistance, suggesting that CSCs must be specifical
Externí odkaz:
https://doaj.org/article/626ebf7a0297497281c3dfce62155e27
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26172 (2011)
Adaptive laboratory evolution (ALE) under controlled conditions has become a valuable approach for the study of the genetic and biochemical basis for microbial adaptation under a given selection pressure. Conventionally, the timescale in ALE experime
Externí odkaz:
https://doaj.org/article/50cca4bea8c449efb5671f1bd33fb773
Autor:
Harish Nagarajan, Jessica E Butler, Anna Klimes, Yu Qiu, Karsten Zengler, Joy Ward, Nelson D Young, Barbara A Methé, Bernhard Ø Palsson, Derek R Lovley, Christian L Barrett
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10922 (2010)
State-of-the-art DNA sequencing technologies are transforming the life sciences due to their ability to generate nucleotide sequence information with a speed and quantity that is unapproachable with traditional Sanger sequencing. Genome sequencing is
Externí odkaz:
https://doaj.org/article/a37fbc30ee124fdc8fe736ec459fb4f8
Publikováno v:
PLoS Computational Biology, Vol 2, Iss 5, p e52 (2006)
The number of complete, publicly available genome sequences is now greater than 200, and this number is expected to rapidly grow in the near future as metagenomic and environmental sequencing efforts escalate and the cost of sequencing drops. In orde
Externí odkaz:
https://doaj.org/article/027146537c7147a6b263f216cfe28246
Autor:
Christian L. Barrett, Angeles Estelles, Taguchi Alex T, Hauser Kevin Eduard, Morin Andrew, Isaac Bright, Matt Greving, Bing Li, Mohan Srinivasan, Gip Phung Tu, Willis Jordan R, Oleg Gurinovich, Piotr Zalicki, Hanako Daino-Laizure
Publikováno v:
Cancer Research. 80:6055-6055
Therapeutic antibodies have contributed significantly to better clinical outcomes across multiple tumor types. However, there is still unmet clinical need in cancers with an immunosuppressive and stroma rich tumor microenvironment (TME). One key limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad700aa19bc91f84e6e19293dd86a196
https://doi.org/10.1158/1538-7445.am2020-6055
https://doi.org/10.1158/1538-7445.am2020-6055
Autor:
Catriona Jamieson, Maurizio Pellecchia, Wenxue Ma, Lawrence S.B. Goldstein, Alice Y. Shih, Maryla Krajewska, Kelly A. Frazer, Janine M. Low-Marchelli, Anil Sadarangani, John C. Reed, Karen Messer, Ifat Geron, Minya Pu, Christian L. Barrett, Dayong Zhai, Sheldon R. Morris, Lei Bao, Daniel Goff, Hye Jung E. Chun, Jessica M. Rusert, Thomas J. Hudson, Angela Court Recart, Kim Hien T. Dao, Peggy Wentworth, Mark D. Minden, Ryan Chuang, Christina Jamieson, Jason Gotlib, Kristen M. Smith, Jun Wei, Kamran Shazand, Giovanni Martinelli, Heather Leu, Marco A. Marra, Larisa Balaian
Publikováno v:
Cell Stem Cell. 12(3):316-328
SummaryLeukemia stem cells (LSCs) play a pivotal role in the resistance of chronic myeloid leukemia (CML) to tyrosine kinase inhibitors (TKIs) and its progression to blast crisis (BC), in part, through the alternative splicing of self-renewal and sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcec4d248dc5222d4c3b8491f2ea003d
Autor:
Anil Sadarangani, Maria A. Zipeto, Leslie Crews, Cayla Mason, Daniel Goff, Mark D. Minden, Sheldon R. Morris, Marco A. Marra, Russell Wall, Kelly A. Frazer, Hye Jung E. Chun, Angela C. Court, Gabriel Pineda, Qingfei Jiang, Larisa Balaian, Ifat Geron, Nathaniel Delos Santos, Catriona Jamieson, Maurizio Pellecchia, Christian L. Barrett
Publikováno v:
Cell stem cell, vol 19, iss 2
Post-transcriptional adenosine-to-inosine RNA editing mediated by adenosine deaminase acting on RNA1 (ADAR1) promotes cancer progression and therapeutic resistance. However, ADAR1 editase-dependent mechanisms governing leukemia stem cell (LSC) genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3959f35de561890f64dd896e3040d7ee
https://escholarship.org/uc/item/04z5f0f3
https://escholarship.org/uc/item/04z5f0f3
Autor:
Zarath M. Summers, Christian L. Barrett, Pier-Luc Tremblay, Derek R. Lovley, Richard H. Glaven, Karsten Zengler, Yu Qiu, Kelly P. Nevin, Bernhard O. Palsson
Publikováno v:
Environmental Microbiology. 13:13-23
The stimulation of subsurface microbial metabolism often associated with engineered bioremediation of groundwater contaminants presents subsurface microorganisms, which are adapted for slow growth and metabolism in the subsurface, with new selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75084dc0effdfe7c2a58b9602f2df860
https://doi.org/10.1111/j.1462-2920.2010.02302.x
https://doi.org/10.1111/j.1462-2920.2010.02302.x
Autor:
Anna Klimes, Richard H. Glaven, Ashley E. Franks, Hoa Tran, Christian L. Barrett, Derek R. Lovley, Karsten Zengler, Yu Qiu
Publikováno v:
FEMS Microbiology Letters. 310:62-68
The pili of Geobacter sulfurreducens are of interest because of the apparent importance of the type IV pili in extracellular electron transfer. A strain of G. sulfurreducens, designated strain MA, produced many more pili than the previously studied D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a2ebadf4072d6d5e2c41aade79cb811
https://doi.org/10.1111/j.1574-6968.2010.02046.x
https://doi.org/10.1111/j.1574-6968.2010.02046.x