Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Christian L Lino Cardenas"'
Autor:
Nicolas Pottier, Thomas Maurin, Benoit Chevalier, Marie-Pierre Puisségur, Kevin Lebrigand, Karine Robbe-Sermesant, Thomas Bertero, Christian L Lino Cardenas, Elisabeth Courcot, Géraldine Rios, Sandra Fourre, Jean-Marc Lo-Guidice, Brice Marcet, Bruno Cardinaud, Pascal Barbry, Bernard Mari
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6718 (2009)
BackgroundEpithelial-mesenchymal interactions are critical in regulating many aspects of vertebrate embryo development, and for the maintenance of homeostatic equilibrium in adult tissues. The interactions between epithelium and mesenchyme are believ
Externí odkaz:
https://doaj.org/article/da634101c6334be0ac3b1a75d7b27ff8
Autor:
Christian L. Lino Cardenas, Wanlin Jiang, Lova P. Kajuluri, Kuldeep Singh, Katrina Ostrom, Rebecca Li, Francois Cherbonneau, Sophie Boerboom, Claire Birchenough, Kangsan Roh, Elizabeth L. Chou, Zarbafian Shahrooz, Christopher Nicholson, Adam L. Johnson, Sujin Lee, Fumito Ichinose, Donald B. Bloch, Sagar Nigwekar, Patrick T. Ellinor, Patricia Musolino, Mark E. Lindsay, Zhixun Dou, Clint L. Miller, Rajeev Malhotra
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108360- (2023)
Summary: Vascular calcification is a hallmark of atherosclerotic disease and serves as a strong predictor and risk factor for cardiovascular events. Growing evidence suggests that autophagy may play a protective role in early atherosclerosis. The pre
Externí odkaz:
https://doaj.org/article/dfcb03ed88384b2a8a1a620d55b76971
Autor:
Jose Verdezoto Mosquera, Gaëlle Auguste, Doris Wong, Adam W. Turner, Chani J. Hodonsky, Astrid Catalina Alvarez-Yela, Yipei Song, Qi Cheng, Christian L. Lino Cardenas, Konstantinos Theofilatos, Maxime Bos, Maryam Kavousi, Patricia A. Peyser, Manuel Mayr, Jason C. Kovacic, Johan L.M. Björkegren, Rajeev Malhotra, P. Todd Stukenberg, Aloke V. Finn, Sander W. van der Laan, Chongzhi Zang, Nathan C. Sheffield, Clint L. Miller
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113380- (2023)
Summary: Coronary artery disease (CAD) is characterized by atherosclerotic plaque formation in the arterial wall. CAD progression involves complex interactions and phenotypic plasticity among vascular and immune cell lineages. Single-cell RNA-seq (sc
Externí odkaz:
https://doaj.org/article/f36322cc9dc74a4986bc713522f0f6e4
Autor:
Karla Lucia F. Alvarez, Jorge Aguilar-Pineda, Karin J. Vera-Lopez, Christian L. Lino Cardenas
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101149- (2022)
Summary: Here, we present a protocol to culture primary human vascular smooth muscle cells (VSMCs) under Alzheimer's disease (AD)-like conditions, including steps for morphological characterization with microscopy. We then describe functional assays,
Externí odkaz:
https://doaj.org/article/fcbe4a1fbd3346adbd59c8817af89bfe
Autor:
Doris Wong, Gaëlle Auguste, Christian L. Lino Cardenas, Adam W. Turner, Yixuan Chen, Yipei Song, Lijiang Ma, R. Noah Perry, Redouane Aherrahrou, Maniselvan Kuppusamy, Chaojie Yang, Jose Verdezoto Mosquera, Collin J. Dube, Mohammad Daud Khan, Meredith Palmore, Jaspreet Kalra, Maryam Kavousi, Patricia A. Peyser, Ljubica Matic, Ulf Hedin, Ani Manichaikul, Swapnil K. Sonkusare, Mete Civelek, Jason C. Kovacic, Johan L.M. Björkegren, Rajeev Malhotra, Clint L. Miller
Publikováno v:
Circulation Research, 132(9), 1144-1161. Lippincott Williams & Wilkins
Background: Genome-wide association studies have identified hundreds of loci associated with common vascular diseases, such as coronary artery disease, myocardial infarction, and hypertension. However, the lack of mechanistic insights for many GWAS l
Autor:
Elizabeth L. Chou, Christian L. Lino Cardenas, Mark Chaffin, Alessandro D. Arduini, Dejan Juric, James R. Stone, Glenn M. LaMuraglia, Matthew J. Eagleton, Mark F. Conrad, Eric M. Isselbacher, Patrick T. Ellinor, Mark E. Lindsay
Publikováno v:
JVS-Vascular Science
JVS-Vascular Science, Vol 3, Iss, Pp 41-47 (2022)
JVS-Vascular Science, Vol 3, Iss, Pp 41-47 (2022)
Carotid plaque instability contributes to large vessel ischemic stroke. Although vascular smooth muscle cells (VSMCs) affect atherosclerotic growth and instability, no treatments aimed at improving VSMC function are available. Large genetic studies i
Autor:
Karla Lucia F. Alvarez, Jorge A. Aguilar-Pineda, Michelle M. Ortiz-Manrique, Marluve F. Paredes-Calderon, Bryan C. Cardenas-Quispe, Karin J. Vera-Lopez, Luis D. Goyzueta-Mamani, Miguel A. Chavez-Fumagalli, Gonzalo Davila Del-Carpio, Antero Peralta-Mestas, Patricia L. Musolino, Christian L. Lino Cardenas
Evidence suggests that there may be racial differences in risk factors associated with the development of Alzheimer’s disease and related dementias (ADRD). We used whole genome sequencing analysis and identified a novel combination of three pathoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c284c48c4dca1f5eb1b5311bf143ed
https://doi.org/10.1101/2022.11.17.22282341
https://doi.org/10.1101/2022.11.17.22282341
Autor:
Doris Wong, Gaëlle Auguste, Christian L. Lino Cardenas, Adam W. Turner, Yixuan Chen, Lijiang Ma, R. Noah Perry, Redouane Aherrahrou, Maniselvan Kuppusamy, Chaojie Yang, Jose Verdezoto Mosquera, Collin J. Dube, Mohammad Daud Khan, Meredith Palmore, Maryam Kavousi, Patricia A. Peyser, Ljubica Matic, Ulf Hedin, Ani Manichaikul, Swapnil K. Sonkusare, Mete Civelek, Jason C. Kovacic, Johan L.M. Björkegren, Rajeev Malhotra, Clint L. Miller
BackgroundGenome-wide association studies (GWAS) have identified hundreds of loci associated with common vascular diseases such as coronary artery disease (CAD), myocardial infarction (MI), and hypertension. However, the lack of mechanistic insights
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3e4fad9ef6526ff21d569b44c95f034
https://doi.org/10.1101/2022.07.23.501247
https://doi.org/10.1101/2022.07.23.501247
Autor:
Maryam Kavousi, Maxime M. Bos, Hanna J. Barnes, Christian L. Lino Cardenas, Doris Wong, Christopher J. O’Donnell, Lawrence F. Bielak, Patricia A. Peyser, Rajeev Malhotra, Sander W. van der Laan, Clint L. Miller
Coronary artery calcification (CAC), a measure of subclinical atherosclerosis, predicts symptomatic coronary artery disease. Identifying genetic risk factors for CAC may point to new therapeutic avenues for preventing clinical disease. Here, we condu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81469a31b1ae8b4562df5a10c9113400
https://doi.org/10.1101/2022.05.02.22273844
https://doi.org/10.1101/2022.05.02.22273844
Autor:
Adeline Boileau, Christian L. Lino Cardenas, Audrey Courtois, Lu Zhang, Rodosthenis S. Rodosthenous, Saumya Das, Natzi Sakalihasan, Jean-Baptiste Michel, Mark E. Lindsay, Yvan Devaux
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 16, p 3924 (2019)
Thoracic aortic aneurysm (TAA) can lead to fatal complications such as aortic dissection. Since aneurysm dimension poorly predicts dissection risk, microRNAs (miRNAs) may be useful to diagnose or risk stratify TAA patients. We aim to identify miRNAs
Externí odkaz:
https://doaj.org/article/161a7ce13b524669a15c32270df4908b