Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Christian Koenecke"'
Autor:
Olaf Penack, Mouad Abouqateb, Christophe Peczynski, William Boreland, Zafer Gülbas, Tobias Gedde-Dahl, Cristina Castilla-Llorente, Nicolaus Kröger, Mathias Eder, Alessandro Rambaldi, Francesca Bonifazi, Igor Wolfgang Blau, Matthias Stelljes, Peter Dreger, Ivan Moiseev, Hélène Schoemans, Christian Koenecke, Zinaida Peric
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract There is an increased risk of GVHD and of non-relapse mortality (NRM) after allogeneic stem cell transplantations (alloSCT) when mismatched unrelated donors (MMUD) are used. In Europe, it is standard practice to use rabbit anti-thymocyte glo
Externí odkaz:
https://doaj.org/article/088862a804d845c78b5a8f61b6c2b139
Autor:
Olaf Penack, Christophe Peczynski, William Boreland, Daniel Wolff, Ivan Moiseev, Hélène Schoemans, Christian Koenecke, Charlotte Graham, Zinaida Peric
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
CAR-T cells are in standard clinical use to treat relapsed or refractory hematologic malignancies, such as non-Hodgkin’s lymphoma, multiple myeloma and acute lymphoblastic leukemia. Owing to the rapidly progressing field of CAR-T cell therapy and t
Externí odkaz:
https://doaj.org/article/25db9f05a7204fbdaace030985bd9231
Autor:
Axel Benner, Peter Dreger, Grzegorz W Basak, Christian Koenecke, Olaf Penack, Christophe Peczynski, Lucia López Corral, Ivan Moiseev, Hélène Schoemans, Zinaida Peric, Thomas Luft, Simona Sica, Mutlu Arat, Maija Itäla-Remes, Nicolaas P M Schaap, Michal Karas, Ludek Raida, Thomas Schroeder, Elisabetta Metafuni, Tulay Ozcelik, Brenda M Sandmaier, Lambros Kordelas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background We previously reported that the “Endothelial Activation and Stress Index” (EASIX; ((creatinine×lactate dehydrogenase)÷thrombocytes)) measured before start of conditioning predicts mortality after allogeneic hematopoietic stem cell tr
Externí odkaz:
https://doaj.org/article/60017a9b556c4c1eaccc5b562a3da144
Autor:
Ivan Odak, Lâle M. Bayir, Lennart Riemann, Ruth Sikora, Jessica Schneider, Yankai Xiao, Nora Möhn, Thomas Skripuletz, Gernot Beutel, Matthias Eder, Arnold Ganser, Reinhold Förster, Christian R. Schultze-Florey, Christian Koenecke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Variability or stability might have an impact on treatment success and toxicity of CD19 CAR T-cells. We conducted a prospective observational study of 12 patients treated with Tisagenlecleucel for CD19+ B-cell malignancies. Using a 31-color spectral
Externí odkaz:
https://doaj.org/article/5786ca34b273415fb85d64d76fb3aa83
Autor:
Olaf Penack, Christophe Peczynski, William Boreland, Jessica Lemaitre, Ksenia Afanasyeva, Brian Kornblit, Manuel Jurado, Carmen Martinez, Annalisa Natale, Jose Antonio Pérez-Simón, Lucia Brunello, Daniele Avenoso, Stefan Klein, Zubeyde Nur Ozkurt, Concha Herrera, Stina Wichert, Patrizia Chiusolo, Eleni Gavriilaki, Grzegorz W. Basak, Hélène Schoemans, Christian Koenecke, Ivan Moiseev, Zinaida Peric
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionExtracorporal Photophoresis (ECP) is in clinical use for steroid-refractory and steroid-dependent acute GVHD (SR-aGVHD). Based on recent Phase-III study results, ruxolitinib has become the new standard of care for SR-aGVHD. Our aim was to
Externí odkaz:
https://doaj.org/article/c87c15a038f44831ac8aefe6cd59a145
Autor:
Zinaida Perić, Grzegorz Basak, Christian Koenecke, Ivan Moiseev, Jyoti Chauhan, Sathyaraj Asaithambi, Alexandros Sagkriotis, Sibel Gunes, Olaf Penack
Publikováno v:
JMIR Cancer, Vol 9, p e42905 (2023)
BackgroundGraft-versus-host disease (GVHD) is the major cause of short- and long-term morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Treatment options beyond corticosteroid therapy remain limited, and prolonged trea
Externí odkaz:
https://doaj.org/article/71cc9426d625453487280a813dc9a42d
Autor:
Victoria Panagiota, Johanna Franziska Kerschbaum, Olaf Penack, Catarina M. Stein, Christopher M. Arends, Christian Koenecke, Paulina M. Strzelecka, Arnold Kloos, Laura Wiegand, Alina Lasch, Robert Altwasser, Adriane Halik, Razif Gabdoulline, Julia Thomson, Konstantin Weibl, Georg-Nikolaus Franke, Carolina Berger, Justin Hasenkamp, Francis Ayuk, Il-Kang Na, Gernot Beutel, Ulrich Keller, Lars Bullinger, Gerald Georg Wulf, Nicolaus Kröger, Vladan Vucinic, Michael Heuser, Frederik Damm
Publikováno v:
HemaSphere, Vol 7, Iss 10, p e957 (2023)
Recent evidence revealed important interactions between clonal hematopoiesis (CH) and cellular therapies established for the treatment of hematologic malignancies. The impact of CH on safety, efficacy, and outcome of chimeric antigen receptor (CAR) T
Externí odkaz:
https://doaj.org/article/3ee53a5fe55248a48a4f66fd724ad837
Autor:
Olaf Penack, Christophe Peczynski, Christian Koenecke, Emmanuelle Polge, Robin Sanderson, Ibrahim Yakoub-Agha, Nathalie Fegueux, Michael Daskalakis, Matthew Collin, Peter Dreger, Nicolaus Kröger, Urs Schanz, Adrian Bloor, Arnold Ganser, Caroline Besley, Gerald G. Wulf, Urban Novak, Ivan Moiseev, Hélène Schoemans, Grzegorz W. Basak, Christian Chabannon, Anna Sureda, Bertram Glass, Zinaida Peric
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
We investigated ≥ grade 3 (CTC-AE) organ toxicities for commercial CD19 chimeric antigen receptor T cell (CAR-T cell) products in 492 patients (Axi-Cel; n = 315; Tisa-Cel; n = 177) with Large B-cell Lymphoma in the European Society for Blood and Ma
Externí odkaz:
https://doaj.org/article/d5f9a6ad12ff48e2b04afd5d77a7a7a5
Autor:
Rabia Shahswar, Gernot Beutel, Razif Gabdoulline, Adrian Schwarzer, Arnold Kloos, Christian Koenecke, Michael Stadler, Gudrun Gohring, Yvonne Lisa Behrens, Zhixiong Li, Louisa-Kristin Dallmann, Piroska Klement, Catherin Albert, Martin Wichmann, Yasmine Alwie, Axel Benner, Maral Saadati, Arnold Ganser, Felicitas Thol, Michael Heuser
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
Treatment options for relapsed and refractory acute myeloid leukemia patients (R/R AML) are limited. This retrospective cohort study compares safety and efficacy of fludarabine, cytarabine, and idarubicin (FLA-IDA) without or with venetoclax (FLAVIDA
Externí odkaz:
https://doaj.org/article/3e7c9d7e6a4f485a890f7508ac5f6304
Autor:
Claas Baier, Jiabin Huang, Kerstin Reumann, Daniela Indenbirken, Felicitas Thol, Christian Koenecke, Ella Ebadi, Albert Heim, Franz-Christoph Bange, Sibylle Haid, Thomas Pietschmann, Nicole Fischer
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 11, Iss 1, Pp 1-8 (2022)
Abstract Background Respiratory syncytial virus (RSV) causes community-acquired respiratory tract infections during winter. However, outbreaks in hospitals also occur repeatedly. In particular, patients with hematologic malignancies are at an increas
Externí odkaz:
https://doaj.org/article/aef408e9daed4a1789df9b5a317daa31