Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christian Kascholke"'
Autor:
Jan Krieghoff, Ann-Kristin Picke, Juliane Salbach-Hirsch, Sandra Rother, Christiane Heinemann, Ricardo Bernhardt, Christian Kascholke, Stephanie Möller, Martina Rauner, Matthias Schnabelrauch, Vera Hintze, Dieter Scharnweber, Michaela Schulz-Siegmund, Michael C. Hacker, Lorenz C. Hofbauer, Christine Hofbauer
Publikováno v:
Biomaterials Research, Vol 23, Iss 1, Pp 1-13 (2019)
Abstract Background Delayed bone regeneration of fractures in osteoporosis patients or of critical-size bone defects after tumor resection are a major medical and socio-economic challenge. Therefore, the development of more effective and osteoinducti
Externí odkaz:
https://doaj.org/article/77ef2e29565f47bda429da3a9e156256
Autor:
Christian Kascholke, Hafiz Awais Nawaz, Jan Krieghoff, Maximilian Schmid, Kathleen Schröck, Iram Maqsood, Michael C. Hacker, Caroline Kohn-Polster, Michaela Schulz-Siegmund
Publikováno v:
Journal of Materials Chemistry B. 9:2295-2307
Injectable gelatine-based hydrogels are valuable tools for drug and cell delivery due to their extracellular matrix-like properties that can be adjusted by the degree of cross-linking. We have established anhydride-containing oligomers for the cross-
Autor:
Hafiz Awais, Nawaz, Kathleen, Schröck, Maximilian, Schmid, Jan, Krieghoff, Iram, Maqsood, Christian, Kascholke, Caroline, Kohn-Polster, Michaela, Schulz-Siegmund, Michael C, Hacker
Publikováno v:
Journal of materials chemistry. B. 9(9)
Injectable gelatine-based hydrogels are valuable tools for drug and cell delivery due to their extracellular matrix-like properties that can be adjusted by the degree of cross-linking. We have established anhydride-containing oligomers for the cross-
Autor:
Christian Kascholke, Jan Krieghoff, Annett Starke, Rudi Loth, Michaela Schulz-Siegmund, Michael C. Hacker, Andreas Koenig
Publikováno v:
Polymer Degradation and Stability. 195:109775
Acidification of implant microenvironment and inflammation due to degradation products of high molecular weight poly(α-hydroxy acids) like PLA and PLGA is a risk that can limit their use in regenerative medicine, tissue engineering and drug delivery
Autor:
Stephanie Möller, Michael C. Hacker, Peter Bellstedt, Caroline Kohn-Polster, Tina Loth, Matthias Schnabelrauch, Michaela Schulz-Siegmund, Christian Kascholke
Publikováno v:
Biomacromolecules. 18:683-694
Biomimetic hydrogels are advanced biomaterials that have been developed following different synthetic routes. Covalent postfabrication functionalization is a promising strategy to achieve efficient matrix modification decoupled of general material pr
Autor:
Tina Loth, Marie Schneider, Katharina Sülflow, Michael C. Hacker, Christian Kascholke, Jan-Christoph Simon, Vuk Savkovic, Michaela Schulz-Siegmund
Publikováno v:
Journal of Biomedical Materials Research Part A. 104:3115-3126
Non-invasively based cell treatments of depigmented skin disorders are largely limited by means of cell sampling as much as by their routes of application. Human melanocytes cultivated from the outer root sheath of hair follicle (HUMORS) are among th
Autor:
Stephanie Möller, Martina Rauner, Michael C. Hacker, Ann-Kristin Picke, Matthias Schnabelrauch, Dieter Scharnweber, Sandra Rother, Gloria Ruiz-Gómez, Stefan Rammelt, Vera Hintze, M. Teresa Pisabarro, Juliane Salbach-Hirsch, Ricardo Bernhardt, Michaela Schulz-Siegmund, Christian Kascholke, Christine Hofbauer, Lorenz C. Hofbauer
Publikováno v:
Biomaterials. 96:11-23
Bone fractures in patients with diabetes mellitus heal poorly and require innovative therapies to support bone regeneration. Here, we assessed whether sulfated hyaluronan included in collagen-based scaffold coatings can improve fracture healing in di
Autor:
Christian Kascholke, Mathias Gressenbuch, F. Peter Schulze, Michaela Schulz-Siegmund, Dirk Schumann, Tobias Flath, Michael C. Hacker, Stephan Hendrikx
Publikováno v:
Acta Biomaterialia. 35:318-329
We present a series of organic/inorganic hybrid sol-gel derived glasses, made from a tetraethoxysilane-derived silica sol (100% SiO2) and oligovalent organic crosslinkers functionalized with 3-isocyanatopropyltriethoxysilane. The material was suscept
Autor:
J. M. Klemens, Michael C. Hacker, M. Brandenburger, C. Kohn, Joachim Kohn, Christian Kascholke, N. S. Murthy
Publikováno v:
Biomaterials Science. 4:1605-1621
Toward a new generation of improved nerve guidance conduits (NGCs), novel biomaterials are required to address pressing clinical shortcomings in peripheral nerve regeneration (PNR) and to promote biological performance. A dual-component hydrogel syst
Autor:
Christian Kascholke, Ulf Anderegg, Rudi Hötzel, Tina Loth, Michael C. Hacker, Michaela Schulz-Siegmund
Publikováno v:
Biomacromolecules. 15:2104-2118
Chemically cross-linked gelatin hydrogels are versatile cell-adhesive hydrogel materials that have been established for a variety of biomedical applications. The most prominent cross-linker is glutaraldehyde, which, however, has been described to cau