Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christian K Behrens"'
Autor:
Céline eMonnet, Sylvie eJorieux, Nathalie eFournier, Rémi eUrbain, Khalil eBouayadi, Christophe eDe Romeuf, Christian K Behrens, Alexandre eFontayne, Philippe eMondon
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Despite the reasonably long half-life of IgGs, market pressure for higher patient convenience while conserving efficacy continues to drive IgG half-life improvement. IgG half-life is dependent on the neonatal Fc receptor FcRn, which amongst other fun
Externí odkaz:
https://doaj.org/article/49ab0a8cc9f649339e90cf67b71485d3
Autor:
Philippe Thullier, Arnaud Avril, Jacques Mathieu, Christian K Behrens, Jean-Luc Pellequer, Thibaut Pelat
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65855 (2013)
The lethal toxin (LT) of Bacillus anthracis, composed of the protective antigen (PA) and the lethal factor (LF), plays an essential role in anthrax pathogenesis. PA also interacts with the edema factor (EF, 20% identity with LF) to form the edema tox
Externí odkaz:
https://doaj.org/article/011a98f4ab824f9eba5389c025c766fe
Autor:
Holger Thie, Lars Toleikis, Jiandong Li, Reinhard von Wasielewski, Gunther Bastert, Thomas Schirrmann, Isabel Tourais Esteves, Christian K Behrens, Bénédict Fournes, Nathalie Fournier, Christophe de Romeuf, Michael Hust, Stefan Dübel
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15921 (2011)
So far, human antibodies with good affinity and specificity for MUC1, a transmembrane protein overexpressed on breast cancers and ovarian carcinomas, and thus a promising target for therapy, were very difficult to generate.A human scFv antibody was i
Externí odkaz:
https://doaj.org/article/410497148c32438f88f7d212ea9aa637
Publikováno v:
European Journal of Immunology. 30:725-731
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f755b820ea5b071ef73599e0888f4093
https://doi.org/10.1002/1521-4141(200003)30:3<725::aid-immu725>3.0.co
https://doi.org/10.1002/1521-4141(200003)30:3<725::aid-immu725>3.0.co
Autor:
Anke Müller, Martin Raftery, Günther Schönrich, Christian K. Behrens, Peter H. Krammer, Henning Walczak
Publikováno v:
Journal of Experimental Medicine. 190:1103-1114
Herpes simplex virus type 1 (HSV1), a large DNA-containing virus, is endemic in all human populations investigated. After infection of mucocutaneous surfaces, HSV1 establishes a latent infection in nerve cells. Recently, it was demonstrated that HSV1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82e778d90456f9816dcc973adc5329a0
https://doi.org/10.1084/jem.190.8.1103
https://doi.org/10.1084/jem.190.8.1103
Autor:
Jie-hui Li, Dalia Rosen, Denise Ronen, Christian K. Behrens, Peter H. Krammer, William R. Clark, Gideon Berke
Publikováno v:
The Journal of Immunology. 161:3943-3949
Previous studies with CTL lines and CTL hybridomas have suggested that functional CD95 (APO-1/Fas)-ligand (CD95L) expression on effector CTLs is a consequence of specific CTL-target recognition and TCR triggering of newly transcribed CD95L. Such a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bb968eff8d321362861d68e8ee28fd9
https://doi.org/10.4049/jimmunol.161.8.3943
https://doi.org/10.4049/jimmunol.161.8.3943
Publikováno v:
European journal of immunology. 33(10)
Many tumors express the death ligand CD95L (CD178, APO-1L, FasL) and can kill activated T cells in vitro. This may enable the tumor cells to suppress anti-tumor immune responses, a phenomenon called "tumor counterattack". Preliminary evidence of tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4df6572d9ff6c34c42a69aa65f44915
https://pubmed.ncbi.nlm.nih.gov/14515265
https://pubmed.ncbi.nlm.nih.gov/14515265
Autor:
Thorsten, Storck, Marie-Charlotte, von Brevern, Christian K, Behrens, Julia, Scheel, Alfred, Bach
Publikováno v:
Current opinion in drug discoverydevelopment. 5(1)
Once again, genomics is about to change drug development. Following its major impact on target discovery and assay development, which increased the number of compounds at early stages of the process, genomics is now zeroing in on the prediction of po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c308eb93141540db2c9a9a0b9a87f646
https://pubmed.ncbi.nlm.nih.gov/11865677
https://pubmed.ncbi.nlm.nih.gov/11865677