Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Christian Joukhadar"'
Autor:
Harm Peters, Spies C, Uhrig A, Puhlmann B, Eggers K, Ina Lieker, Christian Joukhadar, H.-H. Neumayer, Dymtro Khadzhynov, Traunmüller F, Torsten Slowinski, König T
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 49:656-665
Background Daptomycin is a novel antibiotic with primarily renal elimination. Methods In an open-label, prospective trial, the pharmacokinetics of daptomycin after single (8 mg/kg BW) and multiple intravenous doses (4 mg/kg BW) at steady state were d
Autor:
Matthias Grossmann, Olena Hochfeld, Staffan Bark, Heinrich Topp, Harald Straatsma, Markus Rothenburger, Martin Westphal, Christian Joukhadar
Publikováno v:
Pharmacology. 88:193-200
Objective: The primary aim of the present investigation was to determine and compare the pharmacokinetic (PK) profiles of inorganic phosphate in serum and urine after intravenous administration of sodium glycerophosphate and inorganic sodium phosphat
Autor:
Wolfgang Graninger, Oliver Mauric, Christiane Thallinger, Karl H. Konz, Sylvia A. Kugler, Samir M. Joukhadar, Florian M. Kovar, Christian Joukhadar
Publikováno v:
Pharmacology. 87:130-134
Background/Aims: We measured the extracellular concentrations of fluconazole in lung tissue of septic and healthy rats. Methods: A single intravenous dose of 6 mg/kg total body weight of fluconazole was administered intravenously to rats following in
Autor:
Paul A. Kyrle, Oswald Wagner, Thomas Schickbauer, Claudia Marsik, Helmuth Haslacher, Thomas Perkmann, Florian M. Kovar, Christian Joukhadar, Georg Endler
Publikováno v:
Wiener klinische Wochenschrift. 122:334-340
Elevated coagulation factor VIII activity has been associated with increased risk for both venous and arterial thrombosis. The current study evaluated the influence of Factor VIII levels and interactions with gender on all cause mortality in a large
Autor:
Friederike Traunmüller, Michael Schintler, Martin Popovic, Karl H. Konz, Julia Metzler, Christian Joukhadar, Erwin Scharnagl, Stephan Spendel, Oliver Mauric
Publikováno v:
Journal of Antimicrobial Chemotherapy. 65:1252-1257
Objectives In the attempt to overcome increasing glycopeptide- and methicillin-resistant soft tissue infections, daptomycin is presently considered as an attractive alternative to the class of glycopeptides. However, daptomycin dosing and its ability
Autor:
George M. Eliopoulos, Christian Joukhadar, Satish K. Pillai, Robert C. Moellering, Christine Wennersten
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:773-777
With the current high prevalence of infection caused by methicillin-resistant Staphylococcus aureus (MRSA) strains but in light of the general belief that β-lactam antibiotics are more effective than vancomycin against infections caused by methicill
Autor:
Wolfgang Knitsch, Hermann Haller, Catrin Eugbers, Stefanie M. Bode-Boeger, Olaf Burkhardt, Friederike Traunmüller, Jens Martens-Lobenhoffer, Carsten Hafer, Christian Joukhadar, Jan T. Kielstein
Publikováno v:
Nephrology Dialysis Transplantation. 25:1537-1541
Background Daptomycin is a new intravenous cyclic lipopeptide antibiotic, licensed for the treatment of complicated skin and soft tissue infections caused by Gram-positive organisms including both susceptible and resistant strains of Staphylococcus a
Publikováno v:
International Journal of Antimicrobial Agents. 34:72-75
Based on clinicians' expectations of high concentrations of telithromycin (TEL) in tissues, combined with its excellent in vitro antimicrobial characteristics, TEL is casually considered as a potential therapeutic option for the therapy of minor case
Autor:
Thomas Schickbauer, Georg Endler, Claudia Marsik, Lili Kazemi-Shirazi, Christian Joukhadar, Oswald Wagner, Stefan Winkler
Publikováno v:
Clinical Chemistry. 54:343-349
Background: C-reactive protein (CRP), an acute-phase protein, is a sensitive systemic marker of inflammation and acute-phase reactions. Testing CRP concentrations at hospital admission may provide information about disease risk and overall survival.
Autor:
Georg Weinlich, Wolfgang Rous, Wolfgang Poeppl, Johannes Griss, Afschin Soleiman, Sophie Skorjanec, Stanislava Tzaneva, Christian Joukhadar, Christiane Thallinger, Daniela Karimian-Teherani
Publikováno v:
Pharmacology. 82:233-238
Objective: In this experimental study, the antineoplastic potential of orally administered rapamycin in human melanoma was evaluated and compared with dacarbazine (DTIC) as well as with the antineoplastic effect of the combination of both drugs. Meth