Výsledky vyhledávání - "Christian J. Band"

Epidermal Growth Factor and Insulin-Induced Deoxyribonucleic Acid Synthesis in Primary Rat Hepatocytes Is Phosphatidylinositol 3-Kinase Dependent and Dissociated from Protooncogene Induction1

Autor: Barry I. Posner, Christian J. Band, Catherine Mounier

Publikováno v: Endocrinology. 140:5626-5634

The mitogenic response to insulin and epidermal growth factor (EGF) was studied in subconfluent and confluent cultures of primary rat hepatocytes. In subconfluent cultures, wortmannin, LY294002, and rapamycin reversed insulin- and EGF-induced [3H]thy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6dd9703f7db8cd1de8dcd31afc4234d2
https://doi.org/10.1210/endo.140.12.7188

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Regulation of Glycogen Synthase in Rat Hepatocytes

Autor: John J.M. Bergeron, Barry I. Posner, Louis Lavoie, Christian J. Band, Mei Kong

Publikováno v: Journal of Biological Chemistry. 274:28279-28285

We examined the signaling pathways regulating glycogen synthase (GS) in primary cultures of rat hepatocytes. The activation of GS by insulin and glucose was completely reversed by the phosphatidylinositol 3-kinase inhibitor wortmannin. Wortmannin als

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c06ce61d888e856d44e4bc1feafaa73a
https://doi.org/10.1074/jbc.274.40.28279

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Phosphatidylinositol 3′-Kinase and p70s6k Are Required for Insulin but Not Bisperoxovanadium 1,10-Phenanthroline (bpV(phen)) Inhibition of Insulin-like Growth Factor Binding Protein Gene Expression

Autor: Barry I. Posner, Christian J. Band

Publikováno v: Journal of Biological Chemistry. 272:138-145

The hormonal regulation of insulin-like growth factor binding protein (IGFBP)-1 and -4 mRNA was compared in serum-free primary rat hepatocyte cultures. The combination of dexamethasone and glucagon (Dex/Gluc) strongly increased IGFBP-1 and IGFBP-4 mR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e58422d0bd371053da42ad49eabd416
https://doi.org/10.1074/jbc.272.1.138

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Human Pharmacokinetic Study of Immediate-Release (Codeine Phosphate) and Sustained-Release (Codeine Contin) Codeine

Autor: Christian J. Band, Pierre R. Band, Michèle Deschamps, Besner Jg, Andrew J. Coldman

Publikováno v: The Journal of Clinical Pharmacology. 34:938-943

The authors compared, in a double-blind, randomized, crossover study in 13 healthy adult volunteers, the single- and multiple-dose pharmacokinetics, relative bioavailability, and side effects of a new oral sustained-release formulation of codeine (SR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417d1ee932ce1533b6c42b6838f52273
https://doi.org/10.1002/j.1552-4604.1994.tb04008.x

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Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen)

Autor: Victor Dumas, Barry I. Posner, Christian J. Band, Jean-Olivier Contreres

Publikováno v: Molecular endocrinology (Baltimore, Md.). 11(13)

Peroxovanadiums (pVs) are potent protein tyrosine phosphatase (PTP) inhibitors with insulin-mimetic properties in vivo and in vitro. We have established the existence of an insulin receptor kinase (IRK)-associated PTP whose inhibition by pVs correlat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26936bbe79a06bb056ee2c900ed497e8
https://pubmed.ncbi.nlm.nih.gov/9415395

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