Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christian J., Isaac"'
Autor:
Alison Rodger, Isabelle Meistermann, Erlend Moldrheim, Christian J. Isaac, Michael J. Hannon, María J. Prieto, Karen J. Sanders, Einar Sletten, Virtudes Moreno
Publikováno v:
Angewandte Chemie. 113:903-908
In the groove! A tetracationic supramolecular cylinder, [Fe2 L3 ]4+ (L=C25 H20 N4 ), with a triple-helical architecture is just the right size to fit into the major groove of DNA and too big to fit into the minor groove. NMR spectroscopic data confir
Synthesis, structure and coordination chemistry of mono- and bis-heterocyclic-ferrocenyl derivatives
Autor:
Christian J. Isaac, William Clegg, Clayton Price, Mark R. J. Elsegood, Benjamin R. Horrocks, Andrew Houlton
Publikováno v:
Journal of Organometallic Chemistry. 598:248-253
The heterocyclic-ferrocenyl derivatives, 1,1′-bis(5-phenanthridine)ferrocene (1) and [Pd{(η5-C5H5)Fe(η5-C5H3(phenanthroline))}Cl] (2), have been prepared and characterised by single-crystal X-ray analyses. These confirm that in 1 the substitution
Publikováno v:
The Analyst. 125:1791-1798
Cyclic voltammetry and differential-pulse voltammetry at mm-sized electrodes were used to measure the decrease in the rate of diffusion of metal complexes upon binding to DNA and to extract the binding constants and effective binding site sizes. A li
Autor:
Benjamin R. Horrocks, Mark R. J. Elsegood, Andrew Houlton, Christian J. Isaac, AE Gibson, William Clegg
Publikováno v:
Journal of the Chemical Society, Dalton Transactions. :3229-3234
Ferrocenyl derivatives of thymine 1, cytosine 2, and uracil and of N2-acetylguanine and 2-amino-6-chloropurine have been prepared from reactions of [Fe(η5-C5H5)(η5-C5H4CH2N(CH3)3)] I with the corresponding pyrimidine or purine base. The predominant
Autor:
Benjamin R. Horrocks, Nicholas H. Rees, Christian J. Isaac, Andrew Houlton, Mark R. J. Elsegood, William Clegg
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
Reaction of ferrocenylmethanol, FcCH2OH, with β-cyano-N,N-diisopropyl chlorophosphoramidite in dichloromethane yields the ferrocenylmethylphosphonate derivative, FcCH2P(O)(N(iPr)2)(OCH2CH2CN), 2a. The crystal and molecular structure of 2a is present
Autor:
Christian J. Isaac, Andrew Houlton, Mark R. J. Elsegood, Clayton Price, Mehmet Aslanoglu, Benjamin R. Horrocks, William Clegg
Publikováno v:
J. Chem. Soc., Dalton Trans.. :4115-4120
The ferrocenylnucleobase conjugates [Fe(η5-C5H5){η5-C5H4CH2NMe2CH2CH2CH2[graphic omitted]H}][BF4]1 and [Fe(η5-C5H5){η5-C5H4CH2[C5H2N4(NH2)]}]2 of thymine and adenine respectively, have been prepared and their crystal and molecular structures dete
Autor:
Nathaniel W. Alcock, Michael J. Hannon, Laura J. Childs, Alison Rodger, Jemma C. Peberdy, Christian J. Isaac, Veronika Reudegger, Christopher R. Pearmund, Jessica M. C. A. Kerckhoffs, Syma Khalid, Isabelle Meistermann
Publikováno v:
Dalton transactions (Cambridge, England : 2003). (7)
The enantiomeric resolution of an extended range of di-metallo supramolecular triple-helical molecules are reported. The ligands for all complexes are symmetric with two units containing an aryl group linked via an imine bond to a pyridine. Alkyl sub
Autor:
Christian J. Isaac, Virtudes Moreno, Syma Khalid, Michael J. Hannon, Alison Rodger, Einar Sletten, Isabelle Meistermann, Erlend Moldrheim, P. Mark Rodger, Jemma C. Peberdy, María J. Prieto
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(8)
We have designed a synthetic tetracationic metallo-supramolecular cylinder that targets the major groove of DNA with a binding constant in excess of 10 7 M −1 and induces DNA bending and intramolecular coiling. The two enantiomers of the helical mo
Autor:
Michael J., Hannon, Virtudes, Moreno, Maria J., Prieto, Erlend, Moldrheim, Einar, Sletten, Isabelle, Meistermann, Christian J., Isaac, Karen J., Sanders, Alison, Rodger
Publikováno v:
Angewandte Chemie (International ed. in English). 40(5)
Autor:
Michael J, Hannon, Virtudes, Moreno, Maria J, Prieto, Erlend, Moldrheim, Einar, Sletten, Isabelle, Meistermann, Christian J, Isaac, Karen J, Sanders, Alison, Rodger
Publikováno v:
Angewandte Chemie (International ed. in English). 40(5)
In the groove! A tetracationic supramolecular cylinder, [Fe