Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Christian J Kwiecien-Delaney"'
1
Akademický článek
Prolonged inflammation leads to ongoing damage after spinal cord injury.
Autor: Jacek M Kwiecien, Wojciech Dabrowski, Beata Dąbrowska-Bouta, Grzegorz Sulkowski, Wendy Oakden, Christian J Kwiecien-Delaney, Jordan R Yaron, Liqiang Zhang, Lauren Schutz, Barbara Marzec-Kotarska, Greg J Stanisz, John P Karis, Lidia Struzynska, Alexandra R Lucas
Publikováno v: PLoS ONE, Vol 15, Iss 3, p e0226584 (2020)
The pathogenesis of spinal cord injury (SCI) remains poorly understood and treatment remains limited. Emerging evidence indicates that post-SCI inflammation is severe but the role of reactive astrogliosis not well understood given its implication in
Externí odkaz: https://doaj.org/article/15113162607b419a9f439cf7a5a68ab5
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2
Akademický článek
Myxoma virus derived immune modulating proteins, M-T7 and Serp-1, reduce early inflammation after spinal cord injury in the rat model
Autor: Jacek M. Kwiecien, Wojciech Dabrowski, Barbara Marzec-Kotarska, Christian J. Kwiecien-Delaney, Jordan R. Yaron, Liqiang Zhang, Lauren Schutz, Alexandra R. Lucas
Publikováno v: Folia Neuropathologica, Vol 57, Iss 1, Pp 41-50 (2019)
Spinal cord injury (SCI)-initiated inflammation was treated with anti-inflammatory reagents. We compared local spinal cord or intraperitoneal infusion of two Myxoma virus derived immune modulating proteins, Serp-1 and M-T7, with dexamethasone (DEX).
Externí odkaz: https://doaj.org/article/d3fc00cdebe54fd1a23693816153ca8a
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3
Akademický článek
Neuroprotective Effect of Subdural Infusion of Serp-1 in Spinal Cord Trauma
Autor: Jacek M. Kwiecien, Wojciech Dabrowski, Bryce J. Kwiecien-Delaney, Christian J. Kwiecien-Delaney, Dorota Siwicka-Gieroba, Jordan R. Yaron, Liqiang Zhang, Kathleen H. Delaney, Alexandra R. Lucas
Publikováno v: Biomedicines, Vol 8, Iss 10, p 372 (2020)
Spinal cord injury (SCI) initiates a severe, destructive inflammation with pro-inflammatory, CD68+/CD163−, phagocytic macrophages infiltrating the area of necrosis and hemorrhage by day 3 and persisting for the next 16 weeks. Inhibition of macropha
Externí odkaz: https://doaj.org/article/41021a12b9564b18aa20557965e6c58a
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5
Neuroprotective Effect of Subdural Infusion of Serp-1 in Spinal Cord Trauma
Autor: Kathleen H. Delaney, Wojciech Dabrowski, Alexandra Lucas, Jacek M. Kwiecien, Christian J. Kwiecien-Delaney, Dorota Siwicka-Gieroba, Jordan R. Yaron, Bryce J. Kwiecien-Delaney, Liqiang Zhang
Publikováno v: Biomedicines, Vol 8, Iss 372, p 372 (2020)
Biomedicines
Spinal cord injury (SCI) initiates a severe, destructive inflammation with pro-inflammatory, CD68+/CD163−, phagocytic macrophages infiltrating the area of necrosis and hemorrhage by day 3 and persisting for the next 16 weeks. Inhibition of macropha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a193ceb7aeeae9119173e4f1f6770077
https://www.mdpi.com/2227-9059/8/10/372
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6
Local Serpin Treatment via Chitosan-Collagen Hydrogel after Spinal Cord Injury Reduces Tissue Damage and Improves Neurologic Function
Autor: Enkidia A. Awo, Christian J. Kwiecien-Delaney, Jordan R. Yaron, Jacek M. Kwiecien, Michelle Burgin, Lauren N. Schutz, Wojciech Dabrowski, Alexandra Lucas, Liqiang Zhang
Publikováno v: Journal of Clinical Medicine
Volume 9
Issue 4
Journal of Clinical Medicine, Vol 9, Iss 1221, p 1221 (2020)
Spinal cord injury (SCI) results in massive secondary damage characterized by a prolonged inflammation with phagocytic macrophage invasion and tissue destruction. In prior work, sustained subdural infusion of anti-inflammatory compounds reduced neuro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec5e7c4bae8758e21ec1a634806a5fb
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7
Prolonged inflammation leads to ongoing damage after spinal cord injury
Autor: Lidia Strużyńska, Barbara Marzec-Kotarska, Alexandra Lucas, Liqiang Zhang, Jordan R. Yaron, Greg J. Stanisz, Christian J. Kwiecien-Delaney, Jacek M. Kwiecien, John P. Karis, Wojciech Dabrowski, Lauren N. Schutz, Wendy Oakden, Grzegorz Sulkowski, B. Dabrowska-Bouta
Publikováno v: PLoS ONE, Vol 15, Iss 3, p e0226584 (2020)
PLoS ONE
The pathogenesis of spinal cord injury (SCI) remains poorly understood and treatment remains limited. Emerging evidence indicates the severity of post-SCI inflammation and an ongoing controversy in the roles of astrocytes with studies identifying ast
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be1a564e65a95f0a41cd338199ceaa6
https://doaj.org/article/15113162607b419a9f439cf7a5a68ab5
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