Výsledky vyhledávání - "Christian J H von Wintersdorff"

Akademický článek

Development and validation of a single-tube multiple-locus variable number tandem repeat analysis for Klebsiella pneumoniae.

Autor: Antoinette A T P Brink, Christian J H von Wintersdorff, Christina F M van der Donk, Anne M M W Peeters, Patrick S Beisser, Ellen E Stobberingh, Petra F G Wolffs

Publikováno v: PLoS ONE, Vol 9, Iss 3, p e91209 (2014)

Genotyping of Klebsiella pneumoniae is indispensable for management of nosocomial infections, monitoring of emerging strains--including extended-spectrum beta-lactamase (ESBL) producers-, and general epidemiology. Such objectives require a high-resol

Externí odkaz: https://doaj.org/article/0c5d023bb9a048769b9931dea5547d1d

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Akademický článek

Infections with the SARS-CoV-2 Delta variant exhibit fourfold increased viral loads in the upper airways compared to Alpha or non-variants of concern

Autor: Christian J. H. von Wintersdorff, Jozef Dingemans, Lieke B. van Alphen, Petra F. G. Wolffs, Brian M. J. W. van der Veer, Christian J. P. A. Hoebe, Paul H. M. Savelkoul

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)

Abstract There has been a growing body of evidence that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant (B.1.617.2) shows enhanced transmissibility and increased viral loads compared to other variants. A recent study ha

Externí odkaz: https://doaj.org/article/13706417e5ac4021862dcdf657d430fe

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Infections caused by the Delta variant (B.1.617.2) of SARS-CoV-2 are associated with increased viral loads compared to infections with the Alpha variant (B.1.1.7) or non-Variants of Concern

Autor: Christian J. P. A. Hoebe, Petra T. Wolffs, Lieke B. van Alphen, Brian M. J. W. van der Veer, Paul H. M. Savelkoul, Jozef Dingemans, Christian J. H. von Wintersdorff

There has been a growing body of evidence that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant (B.1.617.2) shows enhanced transmissibility and increased viral loads compared to other variants. A recent study has even su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::195f9cf06abaf95438f851e83e7ca047
https://doi.org/10.21203/rs.3.rs-777577/v1

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Epidemiological Typing Using WGS

Autor: Paul H. M. Savelkoul, Lieke B van Alphen, Christian J. H. von Wintersdorff

Publikováno v: Application and Integration of Omics-powered Diagnostics in Clinical and Public Health Microbiology ISBN: 9783030621544

Typing methods are continuously developing and improving. The methods aim to discriminate different strains beyond the species identification level. The first methods used to detect strain-specific differences were based on phenotypic characteristics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::999d17c93affc571917c92fed20c2e73
https://doi.org/10.1007/978-3-030-62155-1_5

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Prevalence and abundance of selected genes conferring macrolide resistance genes in COPD patients during maintenance treatment with azithromycin

Autor: Remco S. Djamin, Christian J. H. von Wintersdorff, Paul H. M. Savelkoul, Eefje J. A. Schrauwen, Rene Kerstens, Jan Kluytmans, Menno M. van der Eerden, Sander Talman, Sevim Uzun, Petra F. G. Wolffs

Publikováno v: Antimicrobial Resistance and Infection Control, 9(1):116. BioMed Central
Antimicrobial Resistance and Infection Control
Antimicrobial Resistance and Infection Control, Vol 9, Iss 1, Pp 1-8 (2020)
Antimicrobial Resistance and Infection Control (online), 9(1):116. BioMed Central Ltd.

Objectives Maintenance treatment with macrolide antibiotics has shown to be effective in reducing exacerbations in COPD patients. A major concern with prolonged treatment with antibiotics is the development of bacterial resistance. In this study we d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0804b5d921fc66ef526ef907af9cc98f
https://doi.org/10.1186/s13756-020-00783-w

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Role of the Environment in Transmission of Multiresistant Enterobacter cloacae in a Hematology-Oncology Department

Autor: Erik Beckers, Paul H. M. Savelkoul, Christian J. H. von Wintersdorff, Wil C. van der Zwet, Yvonne Nijsen, Lieke B. van Alphen

Publikováno v: Infection Control & Hospital Epidemiology. 41:s379-s380

Background: The patient environment is increasingly considered a major source of transmission of nosocomial bacteria to patients. In May 2019, a cluster of 3 patients with multiresistant Enterobacter cloacae was discovered in the hematology-oncology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd19b6dde43830fccf063176e439e9a2
https://doi.org/10.1017/ice.2020.1012

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Appearance of vanD-positive Enterococcus faecium in a tertiary hospital in the Netherlands

Autor: Casper Jamin, Henrik Hasman, Jacky Flipse, Christian J. H. von Wintersdorff, Lieke B van Alphen, Frank H. van Tiel, Julius M. van Niekerk

Publikováno v: Scientific Reports
Scientific Reports, 9:6949. Nature Publishing Group
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)

Vancomycin-resistant enterococci (VRE) can rapidly spread through hospitals. Therefore, our hospital employs a screening program whereby rectal swabs are screened for the presence of vanA and vanB, and only PCR-positive broths are cultured on VRE sel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49fee5e7dad1122a0042690f25e555a
https://doi.org/10.1038/s41598-019-42824-4

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Detection of the plasmid-mediated colistin-resistance gene mcr-1 in faecal metagenomes of Dutch travellers

Autor: Christian J. H. von Wintersdorff, Lieke B. van Alphen, Erik Beuken, John Penders, Petra F. G. Wolffs, Paul H. M. Savelkoul, Astrid M. L. Oude Lashof, Julius M. van Niekerk, Ellen E. Stobberingh, Christian J. P. A. Hoebe

Publikováno v: Journal of Antimicrobial Chemotherapy, 71(12), 3416-3419. Oxford University Press
von Wintersdorff, C J H, Wolffs, P F G, van Niekerk, J M, Beuken, E, van Alphen, L B, Stobberingh, E E, Lashof, A M L O, Hoebe, C J P A, Savelkoul, P H M & Penders, J 2016, ' Detection of the plasmid-mediated colistin-resistance gene mcr-1 in faecal metagenomes of Dutch travellers ', Journal of Antimicrobial Chemotherapy, vol. 71, no. 12, pp. 3416-3419 . https://doi.org/10.1093/jac/dkw328

Background: Recently, the first plasmid-mediated colistin-resistance gene, mcr-1, was reported. Colistin is increasingly used as an antibiotic of last resort for the treatment of infections caused by carbapenem-resistant bacteria, which have been rap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ef8b18e1f9bc3a2c441194619877d4
https://cris.maastrichtuniversity.nl/en/publications/35340f0a-6559-4b0f-a121-3d310d463992

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The gut resistome is highly dynamic during the first months of life

Autor: Paul H. M. Savelkoul, Kerstin Gerhold, John Penders, Eckard Hamelmann, Christian J. H. von Wintersdorff, Petra F. G. Wolffs, Rianne R. R. Nijsen, Susanne Lau

Publikováno v: Future Microbiology, 11(4), 501-510. Future Medicine Ltd.

Aim: We investigated the longitudinal development of several antibiotic resistance genes (ARGs) of the infant gut resistome during the first months after birth. Materials & methods: Fecal samples from 120 infants collected at the ages of 5, 13 and 31

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a831f3b3d0660b2bb47b70e8182b3ce5
https://pubmed.ncbi.nlm.nih.gov/27064174

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