Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Christian Jüngst"'
Autor:
Ayesha Sen, Sebastian Kallabis, Felix Gaedke, Christian Jüngst, Julia Boix, Julian Nüchel, Kanjanamas Maliphol, Julia Hofmann, Astrid C. Schauss, Marcus Krüger, Rudolf J. Wiesner, David Pla-Martín
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Mitochondrial quality control mechanisms prevent damage accumulation, including in mitochondrial DNA (mtDNA). Here, Sen et al. show that altered mtDNA elicits local rearrangements in mitochondrial membrane potential and cristae structure, with mtDNA
Externí odkaz:
https://doaj.org/article/09a00f8e2ea74f67a21ec565d68bba22
Autor:
Lilli Winter, Ilona Staszewska-Daca, Stefan Zittrich, Fatiha Elhamine, Michaela M. Zrelski, Katy Schmidt, Irmgard Fischer, Christian Jüngst, Astrid Schauss, Wolfgang H. Goldmann, Robert Stehle, Gerhard Wiche
Publikováno v:
Cells, Vol 12, Iss 23, p 2677 (2023)
The authors wish to make the following changes to their paper [...]
Externí odkaz:
https://doaj.org/article/63360e1d705a4009870a0f8d8307472c
Autor:
Lilli Winter, Ilona Staszewska-Daca, Stefan Zittrich, Fatiha Elhamine, Michaela M. Zrelski, Katy Schmidt, Irmgard Fischer, Christian Jüngst, Astrid Schauss, Wolfgang H. Goldmann, Robert Stehle, Gerhard Wiche
Publikováno v:
Cells, Vol 12, Iss 9, p 1259 (2023)
Plectin, a highly versatile cytolinker protein, is crucial for myofiber integrity and function. Accordingly, mutations in the human gene (PLEC) cause several rare diseases, denoted as plectinopathies, with most of them associated with progressive mus
Externí odkaz:
https://doaj.org/article/04d7c53ac5b74a79bb6c1a7c99d0f4fa
Autor:
Matthias Rübsam, Aaron F. Mertz, Akiharu Kubo, Susanna Marg, Christian Jüngst, Gladiola Goranci-Buzhala, Astrid C. Schauss, Valerie Horsley, Eric R. Dufresne, Markus Moser, Wolfgang Ziegler, Masayuki Amagai, Sara A. Wickström, Carien M. Niessen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
In multi-layered epithelia tight junctions (TJ) are confined to the most suprabasal viable layer. Here the authors show that this is regulated by ubiquitously localized E-cadherin tuning junctional tension and EGFR activity to inhibit TJ formation in
Externí odkaz:
https://doaj.org/article/13725cc72379417abbcc0dbb0fa23102
Autor:
Nina Koliha, Yvonne Wiencek, Ute Heider, Christian Jüngst, Nikolay Kladt, Susanne Krauthäuser, Ian C. D. Johnston, Andreas Bosio, Astrid Schauss, Stefan Wild
Publikováno v:
Journal of Extracellular Vesicles, Vol 5, Iss 0, Pp 1-15 (2016)
The surface protein composition of extracellular vesicles (EVs) is related to the originating cell and may play a role in vesicle function. Knowledge of the protein content of individual EVs is still limited because of the technical challenges to ana
Externí odkaz:
https://doaj.org/article/9b46bae7f3e94cb99d546dac18da16fd
Autor:
Alessandro Torgovnick, Jan Michel Heger, Vasiliki Liaki, Jörg Isensee, Anna Schmitt, Gero Knittel, Arina Riabinska, Filippo Beleggia, Lucie Laurien, Uschi Leeser, Christian Jüngst, Florian Siedek, Wenzel Vogel, Niklas Klümper, Hendrik Nolte, Maike Wittersheim, Lars Tharun, Roberta Castiglione, Marcus Krüger, Astrid Schauss, Sven Perner, Manolis Pasparakis, Reinhard Büttner, Thorsten Persigehl, Tim Hucho, Grit Sophie Herter-Sprie, Björn Schumacher, Hans Christian Reinhardt
Publikováno v:
Cell Reports, Vol 25, Iss 4, Pp 1027-1039.e6 (2018)
Summary: Cdkn1a, which encodes p21, functions as a major route for p53-mediated cell-cycle arrest. However, the consequence of Cdkn1a gene dosage on tumor suppression has not been systematically investigated. Here, we employed BAC transgenesis to gen
Externí odkaz:
https://doaj.org/article/662c648938254acfa54677dfa23bd2fb
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 12, Pp 3419-3429 (2013)
During the adipogenic differentiation process of mesenchymal stem cells, lipid droplets (LDs) grow slowly by transferring lipids between each other. Recent findings hint at the possibility that a fusion pore is involved. In this study, we analyze lip
Externí odkaz:
https://doaj.org/article/a38f41352b0442bf8710106d9eaf161c
Autor:
Chrisovalantis Papadopoulos, Genny Orso, Giuseppe Mancuso, Marija Herholz, Sentiljana Gumeni, Nimesha Tadepalle, Christian Jüngst, Anne Tzschichholz, Astrid Schauss, Stefan Höning, Aleksandra Trifunovic, Andrea Daga, Elena I Rugarli
Publikováno v:
PLoS Genetics, Vol 11, Iss 4, p e1005149 (2015)
Mutations in SPAST, encoding spastin, are the most common cause of autosomal dominant hereditary spastic paraplegia (HSP). HSP is characterized by weakness and spasticity of the lower limbs, owing to progressive retrograde degeneration of the long co
Externí odkaz:
https://doaj.org/article/3da9f1dff82e4b5a9eb79bfa2290ca50
Autor:
Jördis Klose, Lu Li, Melanie Pahl, Farina Bendt, Ulrike Hübenthal, Christian Jüngst, Patrick Petzsch, Astrid Schauss, Karl Köhrer, Ping Chung Leung, Chi Chiu Wang, Katharina Koch, Julia Tigges, Xiaohui Fan, Ellen Fritsche
Publikováno v:
Cell Biology and Toxicology. 39:319-343
Adverse outcome pathways (AOPs) are organized sequences of key events (KEs) that are triggered by a xenobiotic-induced molecular initiating event (MIE) and summit in an adverse outcome (AO) relevant to human or ecological health. The AOP framework ca
Autor:
Axel Witt, Sebastian Willenborg, Oliver Coutelle, Manolis Pasparakis, Carlos T. Moraes, Martin Krönke, Saskia Diana Günther, C. Lucas, Marie-Christine Albert, Sabine A. Eming, Susanne Brodesser, Lars Schiffmann, Jens M. Seeger, Christiane J. Bruns, F. Heintges-Kleinhofer, Fabian Schorn, Hamid Kashkar, Christian Jüngst, J. P. Werthenbach, Melanie Fritsch
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
The vasculature represents a highly plastic compartment, capable of switching from a quiescent to an active proliferative state during angiogenesis. Metabolic reprogramming in endothelial cells (ECs) thereby is crucial to cover the increasing cellula