Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Christian J, Rudolph"'
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Faithful transmission of the genome from one generation to the next is key to life in all cellular organisms. In the majority of bacteria, the genome is comprised of a single circular chromosome that is normally replicated from a single origin, thoug
Externí odkaz:
https://doaj.org/article/9a946df21d9244c0953651e3619f0ffe
Artificial sweeteners inhibit multidrug‐resistant pathogen growth and potentiate antibiotic activity
Autor:
Rubén de Dios, Chris R Proctor, Evgenia Maslova, Sindija Dzalbe, Christian J Rudolph, Ronan R McCarthy
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 1, Pp n/a-n/a (2023)
Abstract Antimicrobial resistance is one of the most pressing concerns of our time. The human diet is rich with compounds that alter bacterial gut communities and virulence‐associated behaviours, suggesting food additives may be a niche for the dis
Externí odkaz:
https://doaj.org/article/1f873535607c445a86cfeef0d7b1bd89
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Each cell division requires the complete and accurate duplication of the entire genome. In bacteria, the duplication process of the often-circular chromosomes is initiated at a single origin per chromosome, resulting in two replication forks that tra
Externí odkaz:
https://doaj.org/article/cba11620ddb2471bbc1659ce5b28787b
Artificial sweeteners inhibit multidrug‐resistant pathogen growth and potentiate antibiotic activity
Autor:
Rubén de Dios, Chris R Proctor, Evgenia Maslova, Sindija Dzalbe, Christian J Rudolph, Ronan R McCarthy
Publikováno v:
EMBO Molecular Medicine. 15
Disclosure and competing interests statement: Brunel University London has two patents covering the therapeutic use of artificial sweeteners and their use to potentiate antibiotic activity. Data availability The RNA-seq datasets produced in this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc7de2b7a6acfb462a4fc1549953bbe
https://doi.org/10.15252/emmm.202216397
https://doi.org/10.15252/emmm.202216397
Publikováno v:
J Biol Chem
Data availability: Data not included in the manuscript or supporting information can be obtained on request by contacting the corresponding author (Michelle Hawkins: michelle.hawkins@york.ac.uk). Copyright © 2021 The Authors. The complete and accura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1960fecc0a6f94afc1edabc81ec878
https://eprints.whiterose.ac.uk/180479/7/PIIS0021925821012163.pdf
https://eprints.whiterose.ac.uk/180479/7/PIIS0021925821012163.pdf
Autor:
Juachi U. Dimude, Anna Stockum, Sarah L. Midgley-Smith, Amy L. Upton, Helen A. Foster, Arshad Khan, Nigel J. Saunders, Renata Retkute, Christian J. Rudolph
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT Chromosome replication is regulated in all organisms at the assembly stage of the replication machinery at specific origins. In Escherichia coli, the DnaA initiator protein regulates the assembly of replication forks at oriC. This regulation
Externí odkaz:
https://doaj.org/article/79b4d77668a248bfa16f07df16ae890e
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7928, p 7928 (2021)
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7928, p 7928 (2021)
Copyright: © 2021 by the authors. Termination of DNA replication, the final stage of genome duplication, is surprisingly complex, and failures to bring DNA synthesis to an accurate conclusion can impact genome stability and cell viability. In Escher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6653d8c5993f5a65da51fc7bead064dc
https://bura.brunel.ac.uk/handle/2438/23004
https://bura.brunel.ac.uk/handle/2438/23004
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology, Vol 11 (2020)
Copyright © 2020 Syeda, Dimude, Skovgaard and Rudolph. Each cell division requires the complete and accurate duplication of the entire genome. In bacteria, the duplication process of the often-circular chromosomes is initiated at a single origin per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::709cceefebca9d675e1142c64a83450d
http://europepmc.org/articles/PMC7174701
http://europepmc.org/articles/PMC7174701
Publikováno v:
#N#eLS#N#
Most bacteria and archaea have circular chromosomes, in which DNA replication begins at a site known as an origin of replication. Double‐stranded DNA unwound at the origin creates two replication forks that are engaged by DNA polymerase complexes (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6db18557b3b88f2f50f0d4fba2e7257
http://bura.brunel.ac.uk/handle/2438/17437
http://bura.brunel.ac.uk/handle/2438/17437
Publikováno v:
Nucleic Acids Research
Chromosome duplication initiates via the assembly of replication fork complexes at defined origins, from where they proceed in opposite directions until they fuse with a converging fork. Recent work highlights that the completion of DNA replication i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16830385ca404c506911c862abe84ad0
https://pubmed.ncbi.nlm.nih.gov/30544222
https://pubmed.ncbi.nlm.nih.gov/30544222