Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christian J, Madson"'
Autor:
Cameron J Schweitzer, John M Matthews, Christian J Madson, Meghan R Donnellan, Ronald L Cerny, Michael Belshan
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40537 (2012)
HIV-1 exploits numerous host cellular pathways for productive infection. To identify novel factors involved in HIV-1 replication, HIV-1 integrase and matrix protein complexes were captured at 4 hours post infection for proteomic analysis using an aff
Externí odkaz:
https://doaj.org/article/7dec69fa86314307bb71ea0bb2990a23
Publikováno v:
Virology. 489:282-291
Cyclophilin B (CypB) is a member of the immunophilin family and intracellular chaperone. It predominantly localizes to the ER, but also contains a nuclear localization signal and is secreted from cells. CypB has been shown to interact with the Gag pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac912e3c933ded670525b9d29dddd2c
https://doi.org/10.1016/j.virol.2015.12.015
https://doi.org/10.1016/j.virol.2015.12.015
Autor:
Christian J. Madson, Pawel Ciborowski, Michael Belshan, Nicole A. Haverland, Teena Jagadish, Jason DeBoer
Publikováno v:
Virology. :409-420
Virus infection of a cell involves the appropriation of host factors and the innate defensive response of the cell. The identification of proteins critical for virus replication may lead to the development of novel, cell-based inhibitors. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5bade3a32cde4f7e93f1246a74d826
Autor:
Periyasamy Palsamy, Toshimichi Shinohara, Christian J. Madson, Rajan Elanchezhian, Andrew Troia, Michael L. Mulhern
Publikováno v:
Biomedicine & Aging Pathology. 2:143-150
Retinitis pigmentosa (RP) is associated with the expression of a mutant photoreceptor-specific protein. We hypothesized that missorted mutant rhodopsin induces an evolutionarily conserved compensatory mechanism known as the unfolded protein response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a91131d41a726fb981a825f0918ddac
https://doi.org/10.1016/j.biomag.2012.10.003
https://doi.org/10.1016/j.biomag.2012.10.003
Publikováno v:
Journal of Virological Methods. 171:299-302
Previous work demonstrated recently the adaptation of the Escherichia coli biotin ligase BirA – biotin acceptor sequence (BAS) labeling system to produce human immunodeficiency virus type 1 viruses with biotinylated integrase (NLXINB) and matrix (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96462cf584118e25ca11d4f7016b0a2
https://doi.org/10.1016/j.jviromet.2010.11.005
https://doi.org/10.1016/j.jviromet.2010.11.005
Autor:
You Zhou, Christian J. Madson, Yan Li, Bridget Sanford, Han Chen, Michael Belshan, Connor J. Maly
The matrix (MA) protein of HIV-1 is the N-terminal component of the Gag structural protein and is critical for the early and late stages of viral replication. MA contains five α-helices (α1–α5). Deletions in the N-terminus of α5 as small as thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a573d74efc35dd02ff4d2384174184a7
https://europepmc.org/articles/PMC4253686/
https://europepmc.org/articles/PMC4253686/
Autor:
David W. Lynch, Periyasamy Palsamy, Christian J. Madson, Rajan Elanchezhian, Toshimichi Shinohara
Publikováno v:
Chemico-biological interactions. 200(1)
To determine whether high levels of homocysteine (Hcy) induce endoplasmic reticulum (ER) stress with suppression of the nuclear factor-erythroid-2-related factor 2 (Nrf2)-dependent antioxidant protection in lens epithelial cells (LECs). ER stress was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06abc142510eed25588c31b204a37096
https://pubmed.ncbi.nlm.nih.gov/22964297
https://pubmed.ncbi.nlm.nih.gov/22964297
Human lens membranes contain the highest cholesterol concentration of any known biological membranes, but it significantly decreases with age. Oxygenation of cholesterol generates numerous forms of oxysterols (bile acids). We previously showed that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5f5ec7ef3d0961b1857e238432b29a
https://europepmc.org/articles/PMC3156260/
https://europepmc.org/articles/PMC3156260/
Autor:
Michael L, Mulhern, Christian J, Madson, Peter F, Kador, James, Randazzo, Toshimichi, Shinohara
Publikováno v:
Molecular vision. 13
Many cataractogenic stresses also induce endoplasmic reticulum (ER) stress in lens epithelial cells (LECs), which appears to be one of the universal inducers of cell death. In galactosemic rats, activation of ER stress results in the activation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa01b5d8fc0bafb506f9f7f229029082
https://pubmed.ncbi.nlm.nih.gov/17768385
https://pubmed.ncbi.nlm.nih.gov/17768385
Publikováno v:
Medical hypotheses. 70(2)
A mutation in retinal photoreceptor-specific proteins causes nearly 50% of retinitis pigmentosa (RP) cases; the other 50% is called sporadic RP, the etiology of which is unknown. To alleviate RP development, gene therapies, including insertion of a w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83927b3c0d5c3ef13326e96bd2eb1f70
https://pubmed.ncbi.nlm.nih.gov/17590524
https://pubmed.ncbi.nlm.nih.gov/17590524