Výsledky vyhledávání - "Christian I, Uruaka"

Akademický článek

Containment of neuroimmune challenge by diosgenin confers amelioration of neurochemical and neurotrophic dysfunctions in ketamine-induced schizophrenia in mice

Autor: Benneth Ben-Azu, Olusegun G. Adebayo, Aliance R. Fokoua, Jackson E. Onuelu, Jerome N. Asiwe, Emuesiri G. Moke, Itivere A. Omogbiya, Oghenemarho L. Okpara, Jennifer E. Okoro, Omadevuaye M. Oghenevwerutevwe, Christian I. Uruaka

Publikováno v: Brain Disorders, Vol 13, Iss , Pp 100122- (2024)

Inhibition of neuroinflammation through N-methyl-D-aspartate receptor (NMDAR) regulation can provide normalization of neurochemical homeostasis and neurotrophic support in the pathogenesis of psychiatric disorders with complex symptoms such as schizo

Externí odkaz: https://doaj.org/article/14582b6e97df47aaae6b2ac64fd0cb85

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Preventive effects of geraniol in schizophrenia-like symptoms in mice models of psychosis

Autor: Christian I. Uruaka, Udeme O. Georgewill, Owunari A. Georgewill

Publikováno v: International Journal of Research in Medical Sciences. 11:780-788

Background: The pathogenesis of schizophrenia has been linked to N-methyl-D-aspartate receptor (NMDAr) inhibition and DAr hyperfunction. Geraniol is a naturally occurring acyclic monoterpene with diverse pharmacological applications. We aimed to asse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ada18fb89966442e8306147c68975e24
https://doi.org/10.18203/2320-6012.ijrms20230306

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Reversal and Preventive Pleiotropic Mechanisms Involved in the Antipsychotic-Like Effect of Taurine, an Essential β-Amino Acid in Ketamine-Induced Experimental Schizophrenia in Mice

Autor: Benneth Ben-Azu, Christian I. Uruaka, Abayomi M. Ajayi, Thiophilus Aghogho Jarikre, Kingsley E. Nwangwa, Kingsley C. Chilaka, Bienose S. Chijioke, Marymagdalene G. Omonyeme, Chineye B. Ozege, Emmanuella C. Ofili, Ebidenara B. Warekoromor, Nwanneka L. Edigbue, Ufoma V. Esiekpe, Dabrechi E. Akaenyi, Gladys O. Agu

Publikováno v: Neurochemical Research. 48:816-829

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db91beaa761f2a9bab32590933bb91be
https://doi.org/10.1007/s11064-022-03808-5

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Preventive putative mechanisms involved in the psychopathologies of mice passively coping with psychosocial defeat stress by quercetin

Autor: Princewill Ikechukwu, Ugwu, Benneth, Ben-Azu, Sandra Ugonne, Ugwu, Christian I, Uruaka, Chinemerem Choice, Nworgu, Pamela Onyinye, Okorie, Kizito Oluchukwu, Okafor, Kenneth Kelechi, Anachuna, Melford Uche, Elendu, Amogechukwu Onyinye, Ugwu, Ugochukwu Bond, Anyaehie, Azubuike A, Nwankwo, Eme Effiom, Osim

Publikováno v: Brain Research Bulletin. 183:127-141

Derangements of neuroimmune, neurotrophic and neurochemical homeostasis have important implications in psychosocial stress-induced psychopathologies. Whether quercetin, a neuroactive compound, protects against psychosocial stress-induced psychiatric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99933e3a1fe70d0a3a7775f7d610778e
https://doi.org/10.1016/j.brainresbull.2022.03.004

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Evaluation of the role of monoaminergic and nonmonoaminergic systems in the psychotropic effects of morin in mice: an interaction study with receptor blockers

Autor: Solomon Umukoro, Christian I. Uruaka, Itivere Adrian Omogbiya, Adegbuyi Oladele Aderibigbe, Abayomi M. Ajayi, Benneth Ben-Azu, Ezekiel O. Iwalewa

Publikováno v: Nutrire. 46

Treatment-resistance depression and memory impairment disease, burdened with high levels of serious adverse effects of currently existing antidepressants and memory enhancers, have necessitated the search for alternative agents. Although previous pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fed8edcbf2521db245b566acb93ce591
https://doi.org/10.1186/s41110-021-00137-5

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Prevention and reversal of chlorpromazine induced testicular dysfunction in rats by synergistic testicle-active flavonoids, taurine and coenzyme-10

Autor: Tesi P. Edesiri, Benneth Ben-Azu, Mega O. Oyovwi, J. C. Igweh, Victor Emojevwe, Christian I. Uruaka, Rume A. Rotue, E.K. Nwangwa

Publikováno v: Reproductive toxicology (Elmsford, N.Y.). 101

Evidences have shown that alterations in testicular dehydrogenase and ionic-ATPase activities have important implications in spermatogenesis and sperm capacitation, a penultimate biochemical change required for fertilization. Previous studies have re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcaff7654bec3710198d6a0dd2cc7aa1
https://pubmed.ncbi.nlm.nih.gov/33548410

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Repeated endosulfan exposure induces changes in neurochemicals, decreases ATPase transmembrane ionic-pumps, and increased oxidative/nitrosative stress in the brains of rats: Reversal by quercetin

Autor: Edesiri P. Tesi, Rotu A. Rotu, Abioye A. Oyeleke, Christian I. Uruaka, Eneni Okubo Aya-Ebi, Mega O. Oyovwi, Benneth Ben-Azu

Publikováno v: Pesticide Biochemistry and Physiology. 175:104833

Neurochemical and ATPase deregulations play important role in toxicant-induced neurodegeneration. Previous studies have shown that loss of ATPase ionic-pumps alters neurochemical balance via increased ammonia, oxidative and nitrosative stress. Thus,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148111a9e47f2f2fbacf2560735dc669
https://doi.org/10.1016/j.pestbp.2021.104833

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