Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christian Holmgren"'
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 10, Pp 4803-4821 (2022)
Smac mimetics are a group of compounds able to facilitate cell death in cancer cells. TNF-related apoptosis-inducing ligand (TRAIL) is a death receptor ligand currently explored in combination with Smac mimetics. The molecular mechanisms determining
Externí odkaz:
https://doaj.org/article/2370a8b21a8142a89caaa340af35d919
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248175 (2021)
Breast cancer prognosis is frequently good but a substantial number of patients suffer from relapse. The death receptor ligand TRAIL can in combination with Smac mimetics induce apoptosis in some luminal-like ER-positive breast cancer cell lines, suc
Externí odkaz:
https://doaj.org/article/ecfe0d544c034352b26f41daa622ad2b
Autor:
Nadège Gouignard, Tanja Schön, Christian Holmgren, Ina Strate, Emirhan Taşöz, Franziska Wetzel, Marco Maccarana, Edgar M Pera
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191751 (2018)
Chondroitin sulfate (CS)/dermatan sulfate (DS) proteoglycans are abundant on the cell surface and in the extracellular matrix and have important functions in matrix structure, cell-matrix interaction and signaling. The DS epimerases 1 and 2, encoded
Externí odkaz:
https://doaj.org/article/cc82f206a2a04776ba87445cd630a0a6
Publikováno v:
Current Issues in Molecular Biology; Volume 44; Issue 10; Pages: 4803-4821
Smac mimetics are a group of compounds able to facilitate cell death in cancer cells. TNF-related apoptosis-inducing ligand (TRAIL) is a death receptor ligand currently explored in combination with Smac mimetics. The molecular mechanisms determining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::5dba8b231d3e5076b3740355d0b73433
Publikováno v:
Experimental and Molecular Pathology. 125:104739
Breast cancer is the most common malignancy affecting women. Although the prognosis generally is good, a substantial number of patients still suffer from relapse, emphasizing the need for novel treatments. Smac mimetics were developed to facilitate c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e709d11f0670591756e09591cd5a10
https://doi.org/10.1016/j.yexmp.2021.104739
https://doi.org/10.1016/j.yexmp.2021.104739
Autor:
Marco Maccarana, Ina Strate, Edgar M. Pera, Tanja Schön, Christian Holmgren, Emirhan Taşöz, Franziska Wetzel, Nadège Gouignard
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191751 (2018)
PLoS ONE
PLoS ONE
Chondroitin sulfate (CS)/dermatan sulfate (DS) proteoglycans are abundant on the cell surface and in the extracellular matrix and have important functions in matrix structure, cell-matrix interaction and signaling. The DS epimerases 1 and 2, encoded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278219693dc2b2d637ab507578980cfe
https://doi.org/10.1371/journal.pone.0191751
https://doi.org/10.1371/journal.pone.0191751
Publikováno v:
Cell Death Discovery
There is a need for novel strategies to initiate cancer cell death. One approach is the use of Smac mimetics, which antagonize inhibitor of apoptosis proteins (IAPs). Recent studies have shown that combinations of Smac mimetics such as LBW242 or LCL1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322b8721ef4ea290d107140cd2b82f94
http://europepmc.org/articles/PMC4979953
http://europepmc.org/articles/PMC4979953
Publikováno v:
Cancer Research. 74:2285-2285
There is a need for novel strategies to initiate cancer cell death. One approach is the use of Smac mimetics, such as LBW242, which antagonize inhibitor of apoptosis proteins (IAP)s and facilitates cell death. Recent studies have shown that combinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f3d599b274dbd21da0c4eade18e9fa5
https://doi.org/10.1158/1538-7445.am2014-2285
https://doi.org/10.1158/1538-7445.am2014-2285
Autor:
Christian Holmgren, Gry Kalstad Lønne, Katarzyna Chmielarska Masoumi, Christer Larsson, Louise Cornmark
Publikováno v:
BMC Biochemistry
Background Protein kinase C δ (PKCδ) is known to be an important regulator of apoptosis, having mainly pro- but also anti-apoptotic effects depending on context. In a previous study, we found that PKCδ interacts with the pro-apoptotic protein Smac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773aa3f28537e884989114b8132384f9