Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Christian Grätz"'
Autor:
Andrea Forero, Fabrizia Pipicelli, Sylvain Moser, Natalia Baumann, Christian Grätz, Mariano Gonzalez Pisfil, Michael W. Pfaffl, Benno Pütz, Pavel Kielkowski, Filippo M. Cernilogar, Giuseppina Maccarrone, Rossella Di Giaimo, Silvia Cappello
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114755- (2024)
Summary: Cellular crosstalk is an essential process influenced by numerous factors, including secreted vesicles that transfer nucleic acids, lipids, and proteins between cells. Extracellular vesicles (EVs) have been the center of many studies focusin
Externí odkaz:
https://doaj.org/article/7d4ae26e23084530b50fdc23ad49390f
Autor:
Martina Schuster, Frank K. Braun, Dapi Meng-Lin Chiang, Christina Ludwig, Chen Meng, Christian Grätz, Benedikt Kirchner, Martin Proescholdt, Peter Hau, Ortrud K. Steinlein, Michael W. Pfaffl, Markus J. Riemenschneider, Marlene Reithmair
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundNewer 3D culturing approaches are a promising way to better mimic the in vivo tumor microenvironment and to study the interactions between the heterogeneous cell populations of glioblastoma multiforme. Like many other tumors, glioblastoma u
Externí odkaz:
https://doaj.org/article/88fb8fad4ba74612a0fffe87c2cf2659
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Restriction modification (RM) systems are known to provide a strong barrier to the exchange of DNA between and within bacterial species. Likewise, DNA methylation is known to have an important function in bacterial epigenetics regulating essential pa
Externí odkaz:
https://doaj.org/article/d416a7d147d84140b798f7fd6b574c89
Autor:
Christian Grätz, Maria L. U. Bui, Granit Thaqi, Benedikt Kirchner, Robert P. Loewe, Michael W. Pfaffl
Publikováno v:
Life, Vol 12, Iss 3, p 386 (2022)
In this review, we discuss the development pipeline for transcriptional biomarkers in molecular diagnostics and stress the importance of a reliable gene transcript quantification strategy. Hence, a further focus is put on the MIQE guidelines and how
Externí odkaz:
https://doaj.org/article/5004d474adc44b86b20a0f7fff24c3a4
Autor:
Simon Heinze, Petra Kornberger, Christian Grätz, Wolfgang H. Schwarz, Vladimir V. Zverlov, Wolfgang Liebl
Publikováno v:
BMC Microbiology, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background The genus Bacillus includes a great variety of species with potential applications in biotechnology. While species such as B. subtilis or B. licheniformis are well-known and used to provide various products at industrial scale, ot
Externí odkaz:
https://doaj.org/article/4c6550674c764ff3b49caaa1c1fab178
Autor:
Julius C. Holzschuh, Michael Mix, Martin T. Freitag, Tobias Hölscher, Anja Braune, Jörg Kotzerke, Alexis Vrachimis, Paul Doolan, Harun Ilhan, Ioana M. Marinescu, Simon K. B. Spohn, Tobias Fechter, Dejan Kuhn, Christian Gratzke, Radu Grosu, Anca-Ligia Grosu, C. Zamboglou
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract Purpose Convolutional Neural Networks (CNNs) have emerged as transformative tools in the field of radiation oncology, significantly advancing the precision of contouring practices. However, the adaptability of these algorithms across diverse
Externí odkaz:
https://doaj.org/article/3d3b7fb0056c447a9d725656b96a98f4
Autor:
Isis Wolf, Jonas Storz, Susanne Schultze-Seemann, Philipp R. Esser, Stefan F. Martin, Susan Lauw, Peer Fischer, Marie Peschers, Wolfgang Melchinger, Robert Zeiser, Oliver Gorka, Olaf Groß, Christian Gratzke, Reinhard Brückner, Philipp Wolf
Publikováno v:
Bioactive Materials, Vol 41, Iss , Pp 537-552 (2024)
Photoimmunotherapy (PIT) combines the specificity of antibodies with the cytotoxicity of light activatable photosensitizers (PS) and is a promising new cancer therapy. We designed and synthesized, in a highly convergent manner, the silicon phthalocya
Externí odkaz:
https://doaj.org/article/ee35b5cb8cf245868148c021c5ec968b
Autor:
Franz F. Dressler, Falk Diedrichs, Deema Sabtan, Sofie Hinrichs, Christoph Krisp, Timo Gemoll, Martin Hennig, Paulina Mackedanz, Mareile Schlotfeldt, Hannah Voß, Anne Offermann, Jutta Kirfel, Marie C. Roesch, Julian P. Struck, Mario W. Kramer, Axel S. Merseburger, Christian Gratzke, Dominik S. Schoeb, Arkadiusz Miernik, Hartmut Schlüter, Ulrich Wetterauer, Roman Zubarev, Sven Perner, Philipp Wolf, Ákos Végvári
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Urothelial bladder cancer (UC) has a wide tumor biological spectrum with challenging prognostic stratification and relevant therapy-associated morbidity. Most molecular classifications relate only indirectly to the therapeutically relevant p
Externí odkaz:
https://doaj.org/article/5134170881c84f2485111eb97cd4a685
Publikováno v:
Liquid Biopsy in der Onkologie. 19:230-232
Publikováno v:
Extracellular vesicles as biomarkers – in pathophysiology, physical education and home office?. 2:42-47
Liquid biopsy-derived extracellular vesicles (EVs) are an auspicious source for transcriptomic biomarker studies. Here, we review the potential of EV microRNAs (miRNAs) biomarkers, exemplary outline commonly used methods to elucidate new biomarker si