Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Christian Goepfert"'
Autor:
D. Harper, James Z. Appel, L Correa, Michel Awwad, Ian P. J. Alwayn, Hiroshi Kitamura, Simon C. Robson, Christian Goepfert, Robert Sackstein, David K. C. Cooper, Leo Buhler, Eva Csizmadia, Julian D. Down
Publikováno v:
Transplantation. 71:1601-1609
Attempts to induce tolerance though mixed hematopoietic chimerism in the discordant pig-to-baboon xenotransplantation model are sometimes complicated by a potentially fatal thrombotic microangiopathy in the recipient baboons. This state develops imme
Autor:
Simon C. Robson, Christian Goepfert, Yuan Lin, Michel Warny, Elzbieta Kaczmarek, Masato Imai, Jean Sévigny, Keiichi Enjyoji
Publikováno v:
Drug Development Research. 53:193-207
Extracellular nucleotide stimulation of purinergic/pyrimidinergic type-2 (P2) receptors are components of platelet, endothelial cell (EC), and leukocyte activation that culminate in vascular thrombosis and inflammation in vivo. CD39, the prototype nu
Autor:
Leo Buhler, David K. C. Cooper, Christian Goepfert, Simon C. Robson, Ian P. J. Alwayn, James Z. Appel
Publikováno v:
Xenotransplantation. 7:247-257
Activation of endothelial cells and platelet sequestration play major roles in rejection of xenografts. The histopathology of both hyperacute and acute vascular or delayed rejection of vascularized discordant xenografts is characterized by interstiti
Autor:
Olaf Guckelberger, Imrana Qawi, Christian Goepfert, Katarzyna Koziak, Elzbieta Kaczmarek, Masato Imai, Ágnes Kittel, Jan Krzysztof Blusztajn, Jean Sévigny, Jan Schulte am Esch, Simon C. Robson
Publikováno v:
Journal of Biological Chemistry. 275:2057-2062
Ectonucleotidases influence purinergic receptor function by the hydrolysis of extracellular nucleotides. CD39 is an integral membrane protein that is a prototype member of the nucleoside 5'-triphosphate diphosphohydrolase family. The native CD39 prot
Autor:
Johannes Wiekowski, Thomas Engel, Claus Langer, Christian Goepfert, Arnold von Eckardstein, Yoshinari Uehara, Stefan Lorkowski, Christian Schachtrup, Gerd Assmann, Xiaoqin Zhou, Zhengchen Li, Stephan Rust
Publikováno v:
Diabetes. 51(10)
Low HDL cholesterol is a frequent cardiovascular risk factor in diabetes. Because of its pivotal role for the regulation of HDL plasma levels, we investigated in vivo and in vitro regulation of the ATP-binding cassette transporter A1 (ABCA1) by insul
Autor:
Claus Langer, Arnold von Eckardstein, Hans Jansen, Gerlinde von Dehn, Christian Goepfert, Yoshinari Uehara, Thomas Engel, Barbara Gansz, Gerd Assmann
Publikováno v:
Biochemical and biophysical research communications. 296(5)
By lowering high density lipoprotein (HDL) cholesterol, testosterone contributes to the gender difference in HDL cholesterol and has been accused to be pro-atherogenic. The mechanism by which testosterone influences HDL cholesterol is little understo
Publikováno v:
Atherosclerosis. 164(1)
Inhibitors of HMG-CoA reductase (statins) reveal important pharmacological effects in addition to reducing the plasma LDL cholesterol level. In the pathogenesis of arteriosclerosis, transendothelial migration of various leukocytes including monocytes
Autor:
Christian Goepfert, Xiaoqin Zhou, Gerd Assmann, Michael Erren, Arnold von Eckardstein, Thomas Engel
Publikováno v:
Biochemical and biophysical research communications. 291(3)
Deficiency of ABCA1 causes high density lipoprotein deficiency and macrophage foam cell formation in Tangier disease. ABCA1 was also postulated to mediate the secretion of IL-1beta from monocytes and macrophages. We investigated the contribution of A
Autor:
Tomokazu Hoshi, Christian Goepfert, Eva Csizmadia, Simon C. Robson, Keiichi Enjyoji, Christian Sundberg, Jean Sévigny
Publikováno v:
Circulation. 104(25)
Background—Nucleoside triphosphate diphosphohydrolase-1 (NTPDase1)/CD39 is the major ectonucleotidase of endothelial cells and monocytes and catalyzes phosphohydrolysis of extracellular nucleoside diphosphates (NDP) and triphosphates (NTP, eg, ATP
Autor:
David H. Sachs, Q. Chang, Robert Sackstein, R. Wise, Satoshi Gojo, Julian D. Down, Christian Goepfert, Simon C. Robson, David K. C. Cooper, L. Bühler, M. Basker, H. Tsai, Hiroshi Kitamura, Ian P. J. Alwayn
Publikováno v:
Bone Marrow Transplantation, Vol. 27, No 12 (2001) pp. 1227-36
Thrombotic microangiopathy (TM) is a serious complication of bone marrow transplantation (BMT) that resembles thrombotic thrombocytopenic purpura (TTP). In attempting to achieve hematopoietic cell chimerism in the pig-to-baboon model, we have observe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6058641d76b3875917ba8080aa420c
https://archive-ouverte.unige.ch/unige:47550
https://archive-ouverte.unige.ch/unige:47550