Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christian Glover"'
Autor:
Mark C. Bagley, Christian Glover
Publikováno v:
Molecules, Vol 15, Iss 5, Pp 3211-3227 (2010)
Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N-iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total regioco
Externí odkaz:
https://doaj.org/article/ce184114445c4601b63e307db93bab36
Autor:
Christian Glover, Mark C. Bagley
Publikováno v:
Molecules
Molecules, Vol 15, Iss 5, Pp 3211-3227 (2010)
Volume 15
Issue 5
Pages 3211-3227
Molecules, Vol 15, Iss 5, Pp 3211-3227 (2010)
Volume 15
Issue 5
Pages 3211-3227
Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using\ud N-iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions\ud to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total\u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2514c461458033221032c4b1389443
http://europepmc.org/articles/PMC6263277
http://europepmc.org/articles/PMC6263277
Publikováno v:
Synlett. 2007:2459-2482
The results of our research into the Bohlmann-Rahtz -pyridine synthesis are summarized. The historic discovery of this reaction and its mechanism are discussed; followed by recent improvements in methodology, such as Bronsted and Lewis acid catalysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e02a1bada40e29c498acedbc8f2f5bc5
https://doi.org/10.1055/s-2007-986674
https://doi.org/10.1055/s-2007-986674
Publikováno v:
Tetrahedron Letters. 48:7027-7030
The first reported synthesis of saramycetic acid, a degradation product of the complex thiopeptide antibiotic cyclothiazomycin, is achieved in nine steps and 11% overall yield from diethoxyacetonitrile by a strategy, which incorporates two Hantzsch t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc835bfa96ff555f8263fb4d150a7513
https://doi.org/10.1016/j.tetlet.2007.07.111
https://doi.org/10.1016/j.tetlet.2007.07.111
Autor:
Mark C. Bagley, Christian Glover
Publikováno v:
Tetrahedron. 62:66-72
The convergent synthesis of methyl sulfomycinate and sulfomycinic amide, two acidic methanolysis products of the sulfomycin thiopeptide antibiotics, is achieved starting from diethoxyacetonitrile. Further confirmation of structure is obtained by heat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7ff81dcd61b5b3c2774ecc8b30163f3
https://doi.org/10.1016/j.tet.2005.09.134
https://doi.org/10.1016/j.tet.2005.09.134
Publikováno v:
Synlett. :0811-0814
5-Bromo-2,6-dialkylpyridine-4-carboxylates are generated in excellent yield by the Michael addition of enaminoesters and ethynyl ketones followed by bromocyclization using N-bromosuccinimide within 1 hour at 0 °C. Treatment of the same aminopentadie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aafa052cf5c6008b8ba5bbc4a74cc96f
https://doi.org/10.1055/s-2004-820019
https://doi.org/10.1055/s-2004-820019
Publikováno v:
Tetrahedron Letters. 50:4009-4011
A simple and efficient procedure has been developed for the direct formation of epi-4-alkylamino-N-acetylneuraminic acid derivatives as potential inhibitors of influenza neuraminidases. The allylic amination of oxazoline 6 has been effected with a se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eb180b6edf72b84cfb143e75472754d
https://doi.org/10.1016/j.tetlet.2009.03.166
https://doi.org/10.1016/j.tetlet.2009.03.166
Publikováno v:
Synlett. :649-651
The cyclodehydration of Bohlmann-Rahtz aminodienones is catalysed by iodine in ethanol at room temperature to give 2,3,6-trisubstituted pyridines in excellent yield, with total regiocontrol and without the need for chromatographic purification.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08457e9d4a4029fa3baa7105974ea1d5
https://doi.org/10.1055/s-2005-863712
https://doi.org/10.1055/s-2005-863712
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 180(12)
P2X7 receptors (P2X7Rs) are ATP-gated ion channels that trigger caspase-1 activation in the presence of TLR ligands. Inflammatory caspase-1 is responsible for the proteolytic activation of IL-1β. However, the signaling events that couple P2X7Rs to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f094a83daff29a27d2ffa5750c3b7001
https://pubmed.ncbi.nlm.nih.gov/18523309
https://pubmed.ncbi.nlm.nih.gov/18523309
Publikováno v:
ChemInform. 39
The first reported synthesis of saramycetic acid, a degradation product of the complex thiopeptide antibiotic cyclothiazomycin, is achieved in nine steps and 11% overall yield from diethoxyacetonitrile by a strategy, which incorporates two Hantzsch t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2913e6bd857f7b8a43e19b9ac7db2201
https://doi.org/10.1002/chin.200803210
https://doi.org/10.1002/chin.200803210