Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Christian Gerecke"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Ten-eleven translocation proteins (TET1-3) are dioxygenases that oxidize 5-methyldeoxycytosine, thus taking part in passive and active demethylation. TETs have shown to be involved in immune cell development, affecting from self-renewal of stem cells
Externí odkaz:
https://doaj.org/article/97b7c82f011041f3b9093f1f7fea0a21
Publikováno v:
Epigenetics, Vol 15, Iss 3, Pp 307-322 (2020)
Mutations in the enzyme isocitrate dehydrogenase 1 (IDH1) lead to metabolic alterations and a sustained formation of 2-hydroxyglutarate (2-HG). 2-HG is an oncometabolite as it inhibits the activity of α-ketoglutarate-dependent dioxygenases such as t
Externí odkaz:
https://doaj.org/article/34109b6994754f14aa22505543c9096f
Autor:
Maximilian Merz, Hans Salwender, Mathias Haenel, Elias K. Mai, Uta Bertsch, Christina Kunz, Thomas Hielscher, Igor W. Blau, Christof Scheid, Dirk Hose, Anja Seckinger, Anna Jauch, Jens Hillengass, Marc S. Raab, Baerbel Schurich, Markus Munder, Peter Brossart, Christian Gerecke, Hans-Walter Lindemann, Matthias Zeis, Katja Weisel, Jan Duerig, Hartmut Goldschmidt
Publikováno v:
Haematologica, Vol 101, Iss 12 (2016)
Externí odkaz:
https://doaj.org/article/373bd70facef4c0c81e9f948a298e117
Autor:
Christian Straka, Peter Liebisch, Hans Salwender, Burkhard Hennemann, Bernd Metzner, Stefan Knop, Sigrid Adler-Reichel, Christian Gerecke, Hannes Wandt, Martin Bentz, Tim Hendrik Bruemmendorf, Marcus Hentrich, Michael Pfreundschuh, Hans-Heinrich Wolf, Orhan Sezer, Ralf Bargou, Wolfram Jung, Lorenz Trümper, Bernd Hertenstein, Else Heidemann, Helga Bernhard, Nicola Lang, Norbert Frickhofen, Holger Hebart, Ralf Schmidmaier, Andreas Sandermann, Tobias Dechow, Albrecht Reichle, Brigitte Schnabel, Kerstin Schäfer-Eckart, Christian Langer, Martin Gramatzki, Axel Hinke, Bertold Emmerich, Hermann Einsele
Publikováno v:
Haematologica, Vol 101, Iss 11 (2016)
Autologous transplantation is controversial for older patients with multiple myeloma. The role of age-adjusted high-dose melphalan and the impact of induction chemotherapy cycles is still unclear. A total of 434 patients aged 60–70 years were rando
Externí odkaz:
https://doaj.org/article/8484c26faddc436abed9f7a934ff997e
Autor:
Maximilian Merz, Hans Salwender, Mathias Haenel, Elias K. Mai, Uta Bertsch, Christina Kunz, Thomas Hielscher, Igor W. Blau, Christof Scheid, Dirk Hose, Anja Seckinger, Anna Jauch, Jens Hillengass, Marc S. Raab, Baerbel Schurich, Markus Munder, Ingo G.H. Schmidt-Wolf, Christian Gerecke, Hans-Walter Lindemann, Matthias Zeis, Katja Weisel, Jan Duerig, Hartmut Goldschmidt
Publikováno v:
Haematologica, Vol 100, Iss 7 (2015)
We investigated the impact of subcutaneous versus intravenous bortezomib in the MM5 trial of the German-Speaking Myeloma Multicenter Group which compared bortezomib, doxorubicin, and dexamethasone with bortezomib, cyclophosphamide, and dexamethasone
Externí odkaz:
https://doaj.org/article/7fc4d92e3bbe4aef88595a9e2be8e126
PDF - 67K, LNA blocker sequences and reaction conditions for use in Wild-type Blocking (WTB) PCR of selected APC and KRAS segments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831267216a8e94787ca75c6206ddeeb2
https://doi.org/10.1158/1940-6207.22524072.v1
https://doi.org/10.1158/1940-6207.22524072.v1
PDF - 52K, Legend for Supplementary Figure 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356af029f7920e3f6d80861223b46765
https://doi.org/10.1158/1940-6207.22524075.v1
https://doi.org/10.1158/1940-6207.22524075.v1
PDF - 71K, KRAS mutation analysis by WTB-HRM of human colon tissue specimens and control sequencing of HRM products.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58268f7a545be303421d0b063615e75
https://doi.org/10.1158/1940-6207.22524063.v1
https://doi.org/10.1158/1940-6207.22524063.v1
PDF - 35K, Oligonucleotide primers used for High Resolution Melting analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fe9077ac3ac1e85adb7afbf0a1db8d
https://doi.org/10.1158/1940-6207.22524069
https://doi.org/10.1158/1940-6207.22524069
PDF - 857K, Location of primer sets for WTB-HRM analysis in exon 15 of APC. As a first step WTB-PCR was performed by subdividing the MCR into four overlapping segments APC1-4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cc1836f2c88057a4b6584a14f8b284
https://doi.org/10.1158/1940-6207.22524078.v1
https://doi.org/10.1158/1940-6207.22524078.v1