Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Christian Garde"'
Autor:
Anders Jespersen, Daniela Kleine-Kohlbrecher, Nadia Viborg, Mads Lausen, Thomas Trolle, Michail A Pavlidis, Nikolas H Thuesen, Christian Garde, Thomas S Jepsen, Britt W Lauenborg, Birgitte Rønø
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/fc2dbb6a266c43c58f3b25912d31d8f3
Autor:
Julie Massart, Rasmus J. O. Sjögren, Brendan Egan, Christian Garde, Magnus Lindgren, Weifeng Gu, Duarte M. S. Ferreira, Mutsumi Katayama, Jorge L. Ruas, Romain Barrès, Donal J. O’Gorman, Juleen R. Zierath, Anna Krook
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Exercise induces structural and functional adaptations in skeletal muscle that involve transcriptomic remodeling, including of miRNA expression. Here the authors examine the expression of miRNAs in human muscle following exercise training and investi
Externí odkaz:
https://doaj.org/article/16278dcd90674810b94f7f82429c7317
Autor:
Sofie Kirial Mørk, Mohammad Kadivar, Kalijn Fredrike Bol, Arianna Draghi, Marie Christine Wulff Westergaard, Signe Koggersbøl Skadborg, Nana Overgaard, Anders Bundgård Sørensen, Ida Svahn Rasmussen, Lars Vibe Andreasen, Christina Westmose Yde, Thomas Trolle, Christian Garde, Jens Friis-Nielsen, Nis Nørgaard, Dennis Christensen, Jens Vindahl Kringelum, Marco Donia, Sine Reker Hadrup, Inge Marie Svane
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
The majority of neoantigens arise from unique mutations that are not shared between individual patients, making neoantigen-directed immunotherapy a fully personalized treatment approach. Novel technical advances in next-generation sequencing of tumor
Externí odkaz:
https://doaj.org/article/7abb393630304338a7037f295b6ab061
Autor:
Rasmus Birkholm Grønnemose, Christian Garde, Claes Søndergaard Wassmann, Janne Kudsk Klitgaard, Ronni Nielsen, Susanne Mandrup, Andreas Holm Mattsson, Thomas Emil Andersen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Staphylococcus aureus is the cause of serious vascular infections such as sepsis and endocarditis. These infections are notoriously difficult to treat, and it is believed that the ability of S. aureus to invade endothelial cells and persist
Externí odkaz:
https://doaj.org/article/ebcbb48b41e24b86a95acf5c2d1df2bc
Autor:
Emma C. Jappe, Christian Garde, Sri H. Ramarathinam, Ethan Passantino, Patricia T. Illing, Nicole A. Mifsud, Thomas Trolle, Jens V. Kringelum, Nathan P. Croft, Anthony W. Purcell
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Thermostability of the peptide-MHC interaction is important for immunogenicity. Here the authors present a mass spectrometry method to measure thermostability among thousands of peptide-MHC complexes in parallel and a trained artificial neural networ
Externí odkaz:
https://doaj.org/article/5cf6ee2c88c54b69ae8a7c1723f4491d
Publikováno v:
Sensors, Vol 15, Iss 2, Pp 4229-4241 (2015)
Microbial biofilm colonies will in many cases form a smart material capable of responding to external threats dependent on their size and internal state. The microbial community accordingly switches between passive, protective, or attack modes of act
Externí odkaz:
https://doaj.org/article/7e23cb4879434bb99b92c6c36bb5bc06
Autor:
Christian Garde, Michail A. Pavlidis, Pablo Garces, Emma J. Lange, Sri H. Ramarathinam, Mateo Sokač, Kirti Pandey, Pouya Faridi, Johanne Ahrenfeldt, Shanzou Chung, Stine Friis, Daniela Kleine-Kohlbrecher, Nicolai J. Birkbak, Jens V. Kringelum, Birgitte Rønø, Anthony W. Purcell, Thomas Trolle
SUMMARYCancer immunotherapies have greatly improved the treatment of several cancers, albeit a large fraction of patients still does not benefit from such treatments. Personalized therapies are envisioned to lead to improved outcomes, yet they have l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e6d907ea0484dab60693968a532d99f
https://doi.org/10.1101/2023.03.23.533908
https://doi.org/10.1101/2023.03.23.533908
Autor:
Anthony W. Purcell, Jens Vindahl Kringelum, Sri H. Ramarathinam, Patricia T. Illing, Ethan Passantino, Nathan P. Croft, Emma Christine Jappe, Thomas Trolle, Nicole A. Mifsud, Christian Garde
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Jappe, E C, Garde, C, Ramarathinam, S H, Passantino, E, Illing, P T, Mifsud, N A, Trolle, T, Kringelum, J V, Croft, N P & Purcell, A W 2020, ' Thermostability profiling of MHC-bound peptides: a new dimension in immunopeptidomics and aid for immunotherapy design ', Nature Communications, vol. 11, no. 1, 6305 . https://doi.org/10.1038/s41467-020-20166-4
Nature Communications
Jappe, E C, Garde, C, Ramarathinam, S H, Passantino, E, Illing, P T, Mifsud, N A, Trolle, T, Kringelum, J V, Croft, N P & Purcell, A W 2020, ' Thermostability profiling of MHC-bound peptides: a new dimension in immunopeptidomics and aid for immunotherapy design ', Nature Communications, vol. 11, no. 1, 6305 . https://doi.org/10.1038/s41467-020-20166-4
The features of peptide antigens that contribute to their immunogenicity are not well understood. Although the stability of peptide-MHC (pMHC) is known to be important, current assays assess this interaction only for peptides in isolation and not in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2317d1511b0c9109bc62c672896e34
https://doaj.org/article/5cf6ee2c88c54b69ae8a7c1723f4491d
https://doaj.org/article/5cf6ee2c88c54b69ae8a7c1723f4491d
Publikováno v:
Altıntaş, A, Laker, R C, Garde, C, Barrès, R & Zierath, J R 2020, ' Transcriptomic and epigenomics atlas of myotubes reveals insight into the circadian control of metabolism and development ', Epigenomics, vol. 12, no. 8, pp. 701-713 . https://doi.org/10.2217/epi-2019-0391
Aim: Innate circadian rhythms are critical for optimal tissue-specific functions, including skeletal muscle, a major insulin-sensitive tissue responsible for glucose homeostasis. We determined whether transcriptional oscillations are associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b869438c58d47bdae3c08cced87124d
https://doi.org/10.2217/epi-2019-0391
https://doi.org/10.2217/epi-2019-0391
Autor:
Stefan E Seemann, Aashiq H Mirza, Claus H Bang-Berthelsen, Christian Garde, Mikkel Christensen-Dalsgaard, Christopher T Workman, Flemming Pociot, Niels Tommerup, Jan Gorodkin, Walter L Ruzzo
Publikováno v:
Seemann, S E, Mirza, A H, Bang-Berthelsen, C H, Garde, C, Christensen-Dalsgaard, M, Workman, C T, Pociot, F, Tommerup, N, Gorodkin, J & Ruzzo, W L 2022, ' Does rapid sequence divergence preclude RNA structure conservation in vertebrates? ', Nucleic Acids Research, vol. 50, no. 5, pp. 2452-2463 . https://doi.org/10.1093/nar/gkac067
Accelerated evolution of any portion of the genome is of significant interest, potentially signaling positive selection of phenotypic traits and adaptation. Accelerated evolution remains understudied for structured RNAs, despite the fact that an RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722a15d78be38ee42453aecb2cf8b168
https://curis.ku.dk/ws/files/305713907/gkac067.pdf
https://curis.ku.dk/ws/files/305713907/gkac067.pdf