Towards Mimicking the Fetal Liver Niche: The Influence of Elasticity and Oxygen Tension on Hematopoietic Stem/Progenitor Cells Cultured in 3D Fibrin Hydrogels

Autor: Manmohan Bajaj, Burak Toprakhisar, Ramesh Subramani, Herman Ramon, Jennifer Patterson, Carmen Bartic, Catherine M. Verfaillie, Christian Garcia-Abrego, Olivier Deschaume, Stijn Jooken, Samantha Zaunz

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6367, p 6367 (2020)

Hematopoietic stem/progenitor cells (HSPCs) are responsible for the generation of blood cells throughout life. It is believed that, in addition to soluble cytokines and niche cells, biophysical cues like elasticity and oxygen tension are responsible

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3507e3856560ec700e15a5ee25ed4d2e
https://pubmed.ncbi.nlm.nih.gov/32887387