Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christian G. Fabian"'
Autor:
Ulrike G. A. Sattler, Elena Favaro, Lisa Koetz, Wolfgang Mueller-Klieser, Stefano Indraccolo, Christian G. Fabian
Publikováno v:
FEBS Journal. 279:882-891
Many solid tumors show a large variability in glycolytic activity and lactate accumulation, which has been correlated with different metastatic spread, radioresistance and patient survival. To investigate potential differences in protein profiles und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40be9f151e3d712b4dbfec2adc07cc6f
https://doi.org/10.1111/j.1742-4658.2012.08479.x
https://doi.org/10.1111/j.1742-4658.2012.08479.x
Autor:
Ulrike G. A. Sattler, Kristina Goetze, Wolfgang Mueller-Klieser, Andrea Siebers, Daniel Faber, Stefano Indraccolo, Livia Binz, Giorgia Nardo, Christian G. Fabian
Publikováno v:
Cellular oncology (Dordrecht). 38(5)
Malignant transformation of cells is often accompanied by up-regulation of glycolysis-related enzymes and transporters, as well as a distortion of mitochondrial respiration. As a consequence, most malignant tumors utilize high amounts of glucose and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa33d8600406c00554cdedd4df568c92
https://pubmed.ncbi.nlm.nih.gov/26288178
https://pubmed.ncbi.nlm.nih.gov/26288178
Autor:
Ulrike G. A. Sattler, Wolfgang Mueller-Klieser, Sandra S. Meyer, K. Zaleska, Daniel Zips, L.A. Kunz-Schughart, Christian G. Fabian, Ala Yaromina, Michael Baumann
Publikováno v:
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. 188(5)
High pretreatment tumor lactate content is associated with poor outcome after fractionated irradiation in human squamous cell carcinoma (hSCC) xenografts. Therefore, decreasing lactate content might be a promising approach for increasing tumor radios
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b34a4ed94287e8a1c2ad6dd11db058
https://pubmed.ncbi.nlm.nih.gov/22349632
https://pubmed.ncbi.nlm.nih.gov/22349632
Autor:
Christian Hoerner, Verena Quennet, Ala Yaromina, Ulrike G. A. Sattler, Daniel Zips, Christian G. Fabian, Sandra S. Meyer, Stefan Walenta, Hannah Knoerzer, Michael Baumann, Wolfgang Mueller-Klieser
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 94(1)
Background and purpose To study whether pre-therapeutic lactate or pyruvate predict for tumour response to fractionated irradiation and to identify possible coherencies between intermediates of glycolysis and expression levels of selected proteins. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bc789baabe1b965394517503bf80aa
https://pubmed.ncbi.nlm.nih.gov/20036432
https://pubmed.ncbi.nlm.nih.gov/20036432
Autor:
Wolfgang Mueller-Klieser, Kristina Goetze, Christian G. Fabian, Henrike Schroer, Marina Kreutz
Publikováno v:
Cancer Research. 74:3368-3368
In the clinic, tumors showing a pronounced Warburg effect (high lactate tumors) are associated with a higher risk of metastasis and a decreased probability of survival of patients. Therefore, manipulations of the glycolytic pathway may alter tumor ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cafd7f814db2e6413236c56420456c00
https://doi.org/10.1158/1538-7445.am2014-3368
https://doi.org/10.1158/1538-7445.am2014-3368