Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Christian Furlan-Freguia"'
Autor:
Ali Akgul, Christian Furlan Freguia, Massimo Maddaloni, Carol Hoffman, Alexandria Voigt, Cuong Q. Nguyen, Neil A. Fanger, Gary R. Fanger, David W. Pascual
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Sjögren’s Syndrome (SjS) results in loss of salivary and lacrimal gland excretion due to an autoimmune attack on these secretory glands. Conventional SjS treatments address the symptoms, but not the cause of disease. Recognizing this defi
Externí odkaz:
https://doaj.org/article/77ebacf05d39426b90599056829fc0d8
Autor:
Ananta Prasad Arukha, Christian Furlan Freguia, Meerambika Mishra, Jyoti K. Jha, Subhashinie Kariyawasam, Neil A. Fanger, Ellen M. Zimmermann, Gary R. Fanger, Bikash Sahay
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1098 (2021)
Inflammatory bowel disease (IBD) is characterized by gastrointestinal inflammation comprised of Crohn’s disease and ulcerative colitis. Centers for Disease Control and Prevention report that 1.3% of the population of the United States (approximatel
Externí odkaz:
https://doaj.org/article/87ebad7bd9a942dfa799de5cc4e70af1
Autor:
Gary R. Fanger, Meerambika Mishra, Subhashinie Kariyawasam, Christian Furlan Freguia, Ellen M. Zimmermann, Ananta Prasad Arukha, Jyoti K. Jha, Bikash Sahay, Neil Fanger
Publikováno v:
Biomedicines
Volume 9
Issue 9
Biomedicines, Vol 9, Iss 1098, p 1098 (2021)
Volume 9
Issue 9
Biomedicines, Vol 9, Iss 1098, p 1098 (2021)
Inflammatory bowel disease (IBD) is characterized by gastrointestinal inflammation comprised of Crohn’s disease and ulcerative colitis. Centers for Disease Control and Prevention report that 1.3% of the population of the United States (approximatel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067779a28b23d86b27c9522a746ca338
https://doi.org/10.3390/biomedicines9091098
https://doi.org/10.3390/biomedicines9091098
Publikováno v:
Behavioural Brain Research. 392:112701
Intestinal alkaline phosphatase (IAP) is an endogenous enzyme that promotes gastrointestinal homeostasis by detoxifying inflammatory mediators, tightening the gut barrier and promoting a healthy microbiome. Oral IAP administration was efficacious in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e94d2cb613b25fb037f8ec6589fca46
https://doi.org/10.1016/j.bbr.2020.112701
https://doi.org/10.1016/j.bbr.2020.112701
Publikováno v:
Current Topics in Medicinal Chemistry. 16:1118-1134
In the absence of an approved and effective vaccine, topical microbicides have become the strategy of choice to provide women with the ability to prevent the sexual transmission of HIV. Topical microbicides are chemical and physical agents specifical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7572aaf13f759b680d36c4d599d328d6
https://doi.org/10.2174/1568026615666150901113939
https://doi.org/10.2174/1568026615666150901113939
Autor:
Andrea S. Rothmeier, Wolfram Ruf, Patrizia Marchese, Zaverio M. Ruggeri, Christian Furlan-Freguia, Brian G. Petrich, Mark H. Ginsberg
Publikováno v:
The Journal of clinical investigation, vol 125, iss 4
Extracellular ATP is a signal of tissue damage and induces macrophage responses that amplify inflammation and coagulation. Here we demonstrate that ATP signaling through macrophage P2X7 receptors uncouples the thioredoxin (TRX)/TRX reductase (TRXR) s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44551264bf1090cf45099e7977c11e76
https://doi.org/10.1172/jci79329
https://doi.org/10.1172/jci79329
Autor:
Sheila Connelly, Brian Fanelli, Christian Furlan-Freguia, Michael Kaleko, Rita R. Colwell, Nur A. Hasan
Publikováno v:
Open Forum Infectious Diseases
Background Exposure of the gut microbiota to antibiotics can alter the composition of the microbiome and lead to the emergence and spread of antibiotic resistance. SYN-004 (ribaxamase) is a clinical-stage β-lactamase intended to degrade certain IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535800eea91af971e5590c9f4268db7d
http://europepmc.org/articles/PMC6811160
http://europepmc.org/articles/PMC6811160
Autor:
Brian Fanelli, Rita R. Colwell, Michael Kaleko, Sheila Connelly, Christian Furlan Freguia, Nur A. Hasan
Publikováno v:
Gastroenterology. 156:S-241
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a9c70cce62da7f72a78c8349b526b40
https://doi.org/10.1016/s0016-5085(19)37407-4
https://doi.org/10.1016/s0016-5085(19)37407-4
Autor:
Wolfram Ruf, John H. Griffin, Annette von Drygalski, Laurent O. Mosnier, Christian Furlan-Freguia
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:769-776
Objective— To study the role of the endothelial protein C receptor (EPCR) in the modulation of susceptibility to inflammation-induced vascular leak in vivo. Approach and Results— Genetically modified mice with low, low ) and control mice were cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc09a95d6d3b52dcf33ec1fff8e0d880
https://doi.org/10.1161/atvbaha.112.301082
https://doi.org/10.1161/atvbaha.112.301082
Autor:
Joseph Sliman, Sheila Connelly, Nur A. Hasan, Michael Kaleko, Poorani Subramanian, Christian Furlan-Freguia, Andrew Bristol, Steve Hubert
Publikováno v:
Open Forum Infectious Diseases. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8319bd8b8d0fba4a6203b6ff367e3ddd
https://doi.org/10.1093/ofid/ofw172.1769
https://doi.org/10.1093/ofid/ofw172.1769