Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Christian Fritzsch"'
Autor:
Marina Garcia-Moreno, Paul M. Jordan, Kerstin Günther, Therese Dau, Christian Fritzsch, Monika Vermes, Astrid Schoppa, Anita Ignatius, Britt Wildemann, Oliver Werz, Bettina Löffler, Lorena Tuchscherr
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Chronic staphylococcal osteomyelitis can persist for long time periods causing bone destruction. The ability of Staphylococcus aureus to develop chronic infections is linked to its capacity to invade and replicate within osteoblasts and osteocytes an
Externí odkaz:
https://doaj.org/article/71981f99bf094cffbe6c0ab65e997dc3
Autor:
Tanja Lerchl, Kati Nispel, Jannis Bodden, Anjany Sekuboyina, Malek El Husseini, Christian Fritzsche, Veit Senner, Jan S. Kirschke
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Introduction: Achieving an adequate level of detail is a crucial part of any modeling process. Thus, oversimplification of complex systems can lead to overestimation, underestimation, and general bias of effects, while elaborate models run the risk o
Externí odkaz:
https://doaj.org/article/54726e789c534d4eab50fea831c41039
Autor:
Michael Kabesch, Bernd Woitsch, Erika von Mutius, Christian Fritzsch, Stephan K. Weiland, David Carr, Michaela Schedel
Publikováno v:
Journal of Allergy and Clinical Immunology. 117:269-274
Background IgE production, a hallmark of asthma and atopic disease, may be under genetic control. Genes of the IL-4 and IL-13 pathway, central for IgE regulation, have so far only been assessed in studies of single gene effects. Objective Here we ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72fc5e8b071d19184a0d261befd053f5
https://doi.org/10.1016/j.jaci.2005.10.024
https://doi.org/10.1016/j.jaci.2005.10.024
Polymorphismen in der IL-4/IL-13-Signalkaskade beeinflussen die IgE-Regulation und Asthma bronchiale
Autor:
Michaela Schedel, Bernd Woitsch, David Carr, Irene Schmid, S. K. Weiland, M. Kabesch, Christian Fritzsch, E. Von Mutius
Publikováno v:
Allergologie. 28:307-314
Background: The IL-4/IL-13 pathway plays a critical role in the IgE regulation and the development of asthma. Previous studies have described an association between genetic alterations in single genes of the IL-4/IL-13 pathway and these two phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89d47168a5fafab163ea390b6ea6d757
https://doi.org/10.5414/alp28307
https://doi.org/10.5414/alp28307
Autor:
Fernando D. Martinez, Erika von Mutius, Michael Kabesch, Stephan K. Weiland, Claudia Höfler, Iren Tzotcheva, David Carr, Christian Fritzsch
Publikováno v:
Journal of Allergy and Clinical Immunology. 112:893-898
Background IL-4, a cytokine with immunomodulatory functions, is involved in the upregulation of IgE production characteristic of asthma and allergy. Thus far, 2 single nucleotide polymorphisms (SNPs) in the promoter (C-589T) and 5′ untranslated reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af92f572134ed5c0e832bceb10191c76
https://doi.org/10.1016/j.jaci.2003.08.033
https://doi.org/10.1016/j.jaci.2003.08.033
Autor:
Fernando D. Martinez, Mauro Baldini, Robert P. Erickson, Erika von Mutius, Stephan K. Weiland, Penelope E. Graves, Marilyn Halonen, Christian Fritzsch, Michael Kabesch, Catharine J. Holberg
Publikováno v:
Journal of Allergy and Clinical Immunology. 105:506-513
Background: Increased levels of total serum IgE are a strong risk factor for the development of asthma. IgE is also involved in host defenses against parasites and fungi. Linkage of total serum IgE with markers located close to the 3 Mb cluster of cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a269e322c607799ec092696002ff642
https://doi.org/10.1067/mai.2000.104940
https://doi.org/10.1067/mai.2000.104940
Autor:
H. H. Thiemann, Matthias Wjst, Gabi Roell, Christian Fritzsch, Erika von Mutius, S Dold, Peter Reitmeir
Publikováno v:
European Journal of Pediatrics. 153:682-686
The objective of this analysis was to determine the relationship between wheezing at different age groups in children and the prevalence of bronchial hyperreactivity at the age of 10. A population-based cross-sectional study was conducted in Leipzig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6b526590e4a05a312592639a819fb6
https://doi.org/10.1007/bf02190692
https://doi.org/10.1007/bf02190692
Autor:
Peter Reitmeir, H. H. Thiemann, Thomas Nicolai, Christian Fritzsch, E. Von Mutius, Fernando D. Martinez
Publikováno v:
BMJ. 308:692-695
Objective: To investigate the relation between skin test reactivity in children and number of siblings. Design: Cross sectional survey among school-children aged 9-11 years. Skin prick tests in the children and self completion of written questionnair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6544ce6f0f2629b43cd876450502559a
https://doi.org/10.1136/bmj.308.6930.692
https://doi.org/10.1136/bmj.308.6930.692
Publikováno v:
BMJ. 305:1395-1399
OBJECTIVES--To compare the prevalence of asthma and allergic disorders among children in Munich, western Germany, and Leipzig, eastern Germany, where environmental exposure, particularly air concentrations of sulphur dioxide and particulate matter, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8147608f9efdc989854829d7a7c75c6
https://doi.org/10.1136/bmj.305.6866.1395
https://doi.org/10.1136/bmj.305.6866.1395
Autor:
A. William Musk, Erika von Mutius, Michaela Schedel, Youming Zhang, Wolfgang Leupold, Christian Fritzsch, David Carr, Stephan K. Weiland, Alan L. James, Pirro G. Hysi, N. Klopp, William O.C.M. Cookson, Gabriel Núñez, Naohiro Inohara, MF Moffatt, Brenda Boardman, Michael Kabesch
Publikováno v:
Hum. Mol. Genet. 14, 935-941 (2005)
Asthma is a familial inflammatory disease of the airways of the lung. Microbial exposures in childhood protect against asthma through unknown mechanisms. The innate immune system is able to identify microbial components through a variety of pattern-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5503312fdaca5cbe657332ea3a9e4bf5
https://pubmed.ncbi.nlm.nih.gov/15718249
https://pubmed.ncbi.nlm.nih.gov/15718249