Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Christian F. Nielsen"'
Autor:
Hannes Witt, Janni Harju, Emma M.J. Chameau, Charlotte M.A. Bruinsma, Tinka V.M. Clement, Christian F. Nielsen, Ian D. Hickson, Erwin J.G. Peterman, Chase P. Broedersz, Gijs J.L. Wuite
During mitosis in eukaryotic cells, mechanical forces generated by the mitotic spindle pull the sister chromatids into the nascent daughter cells. How do mitotic chromosomes achieve the necessary mechanical stiffness and stability to maintain their i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11e73d92e25300568a6064849cda6653
https://doi.org/10.1101/2023.04.11.536423
https://doi.org/10.1101/2023.04.11.536423
Autor:
Constantijn P. van der Smagt, Christian F. Nielsen, Ian D. Hickson, Erwin J. Peterman, Gijs J. Wuite
Publikováno v:
Biophysical Journal. 122:497a
Publikováno v:
Biophysical Journal. 122:547a
Autor:
Anna E. C. Meijering, Kata Sarlós, Christian F. Nielsen, Hannes Witt, Janni Harju, Emma Kerklingh, Guus H. Haasnoot, Anna H. Bizard, Iddo Heller, Chase P. Broedersz, Ying Liu, Erwin J. G. Peterman, Ian D. Hickson, Gijs J. L. Wuite
Publikováno v:
Nature
Nature, 605(7910), 545-550. Nature Publishing Group
Meijering, A E C, Sarlós, K, Nielsen, C F, Witt, H, Harju, J, Kerklingh, E, Haasnoot, G H, Bizard, A H, Heller, I, Broedersz, C P, Liu, Y, Peterman, E J G, Hickson, I D & Wuite, G J L 2022, ' Nonlinear mechanics of human mitotic chromosomes ', Nature, pp. 545–550 . https://doi.org/10.1038/s41586-022-04666-5
Meijering, A E C, Sarlós, K, Nielsen, C F, Witt, H, Harju, J, Kerklingh, E, Haasnoot, G H, Bizard, A H, Heller, I, Broedersz, C P, Liu, Y, Peterman, E J G, Hickson, I D & Wuite, G J L 2022, ' Nonlinear mechanics of human mitotic chromosomes ', Nature, vol. 605, no. 7910, pp. 545-550 . https://doi.org/10.1038/s41586-022-04666-5
Nature, 605(7910), 545-550. Nature Publishing Group
Meijering, A E C, Sarlós, K, Nielsen, C F, Witt, H, Harju, J, Kerklingh, E, Haasnoot, G H, Bizard, A H, Heller, I, Broedersz, C P, Liu, Y, Peterman, E J G, Hickson, I D & Wuite, G J L 2022, ' Nonlinear mechanics of human mitotic chromosomes ', Nature, pp. 545–550 . https://doi.org/10.1038/s41586-022-04666-5
Meijering, A E C, Sarlós, K, Nielsen, C F, Witt, H, Harju, J, Kerklingh, E, Haasnoot, G H, Bizard, A H, Heller, I, Broedersz, C P, Liu, Y, Peterman, E J G, Hickson, I D & Wuite, G J L 2022, ' Nonlinear mechanics of human mitotic chromosomes ', Nature, vol. 605, no. 7910, pp. 545-550 . https://doi.org/10.1038/s41586-022-04666-5
In preparation for mitotic cell division, the nuclear DNA of human cells is compacted into individualized, X-shaped chromosomes1. This metamorphosis is driven mainly by the combined action of condensins and topoisomerase IIα (TOP2A)2,3, and has been
Autor:
Anna E C, Meijering, Kata, Sarlós, Christian F, Nielsen, Hannes, Witt, Janni, Harju, Emma, Kerklingh, Guus H, Haasnoot, Anna H, Bizard, Iddo, Heller, Chase P, Broedersz, Ying, Liu, Erwin J G, Peterman, Ian D, Hickson, Gijs J L, Wuite
Publikováno v:
Nature. 605(7910)
In preparation for mitotic cell division, the nuclear DNA of human cells is compacted into individualized, X-shaped chromosomes
Autor:
Anna E. C. Meijering, Kata Sarlós, Christian F. Nielsen, Hannes Witt, Janni Harju, Emma Kerklingh, Guus H. Haasnoot, Anna H. Bizard, Iddo Heller, Chase P. Broedersz, Ying Liu, Erwin J. G. Peterman, Ian D. Hickson, Gijs J. L. Wuite
Publikováno v:
Meijering, A E C, Sarlós, K, Nielsen, C F, Witt, H, Harju, J, Kerklingh, E, Haasnoot, G H, Bizard, A H, Heller, I, Broedersz, C P, Liu, Y, Peterman, E J G, Hickson, I D & Wuite, G J L 2022, ' Publisher Correction: Nonlinear mechanics of human mitotic chromosomes ', Nature, vol. 607, no. 7920, E23 . https://doi.org/10.1038/s41586-022-05051-y
In the version of this article initially published, Extended Data Fig. 5 was a duplicate of Extended Data Fig. 6. The correct image is now in place in the HTML and PDF versions of the article.
Publikováno v:
Proc Natl Acad Sci U S A
Topoisomerase IIα (TOP2A) is a core component of mitotic chromosomes and important for establishing mitotic chromosome condensation. The primary roles of TOP2A in mitosis have been difficult to decipher due to its multiple functions across the cell
Autor:
Therese R. Wassberg, Mathilde L. Witt, Murat Serhatlioglu, Christian F. Nielsen, Ian D. Hickson, Anders Kristensen
Publikováno v:
EPJ Web of Conferences. 266:12007
Viscoelastic flow-based particle manipulation techniques enable bio-particle focusing, separation, and enrichment by precisely tuning the rheological parameters, flow conditions, and microchannel geometry. In this study, we fabricated a PDMS-based si
Autor:
Paul, Kalitsis, Tao, Zhang, Ji Hun, Kim, Christian F, Nielsen, Kathryn M, Marshall, Damien F, Hudson
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2004
Condensin, a highly conserved pentameric chromosome complex, is required for the correct organization and folding of the genome. Here, we highlight how to knock protein tags into endogenous loci to faithfully study the condensin complex in vertebrate
Autor:
Ian D. Hickson, Christian F. Nielsen
Publikováno v:
Cell Cycle. 15:2704-2711
PICH is an SNF2-family DNA translocase that appears to play a role specifically in mitosis. Characterization of PICH in human cells led to the initial discovery of "ultra-fine DNA bridges" (UFBs) that connect the 2 segregating DNA masses in the anaph