Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Christian F Lehner"'
Autor:
Zeynep Kabakci, Heidi E Reichle, Bianca Lemke, Dorota Rousova, Samir Gupta, Joe Weber, Alexander Schleiffer, John R Weir, Christian F Lehner
Publikováno v:
PLoS Genetics, Vol 18, Iss 12, p e1010547 (2022)
For meiosis I, homologous chromosomes must be paired into bivalents. Maintenance of homolog conjunction in bivalents until anaphase I depends on crossovers in canonical meiosis. However, instead of crossovers, an alternative system achieves homolog c
Externí odkaz:
https://doaj.org/article/ef341d9f5d6a4438b3c37ad8413598b6
Autor:
Zeynep Kabakci, Hiro Yamada, Luisa Vernizzi, Samir Gupta, Joe Weber, Michael Shoujie Sun, Christian F Lehner
Publikováno v:
PLoS Genetics, Vol 18, Iss 10, p e1010469 (2022)
Meiosis in males of higher dipterans is achiasmate. In their spermatocytes, pairing of homologs into bivalent chromosomes does not include synaptonemal complex and crossover formation. While crossovers preserve homolog conjunction until anaphase I du
Externí odkaz:
https://doaj.org/article/84f3425d83454884854f8bb06d842dbb
Autor:
Luisa Vernizzi, Christian F Lehner
Publikováno v:
PLoS Genetics, Vol 18, Iss 7, p e1010327 (2022)
The bivalent chromosomes that are generated during prophase of meiosis I comprise a pair of homologous chromosomes. Homolog pairing during prophase I must include mechanisms that avoid or eliminate entanglements between non-homologous chromosomes. In
Externí odkaz:
https://doaj.org/article/131b6a9746334ba8b18c9998cb1aea5b
Autor:
Luisa Vernizzi, Christian F Lehner
Publikováno v:
PLoS Genetics, Vol 17, Iss 10, p e1009870 (2021)
Reduction of genome ploidy from diploid to haploid necessitates stable pairing of homologous chromosomes into bivalents before the start of the first meiotic division. Importantly, this chromosome pairing must avoid interlocking of non-homologous chr
Externí odkaz:
https://doaj.org/article/a8d1b51ede404cec8e80e3e624b6a942
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1008928 (2020)
Regular chromosome segregation during the first meiotic division requires prior pairing of homologous chromosomes into bivalents. During canonical meiosis, linkage between homologous chromosomes is maintained until late metaphase I by chiasmata resul
Externí odkaz:
https://doaj.org/article/be01854c664e434c9e127a2cc0effae6
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008162 (2019)
The first meiotic division reduces genome ploidy. This requires pairing of homologous chromosomes into bivalents that can be bi-oriented within the spindle during prometaphase I. Thereafter, pairing is abolished during late metaphase I, and univalent
Externí odkaz:
https://doaj.org/article/c360a6143242413e81dca570d670096c
Autor:
Soumya Chaurasia, Christian F Lehner
Publikováno v:
PLoS Genetics, Vol 14, Iss 5, p e1007372 (2018)
Sister kinetochores are connected to the same spindle pole during meiosis I and to opposite poles during meiosis II. The molecular mechanisms controlling the distinct behavior of sister kinetochores during the two meiotic divisions are poorly underst
Externí odkaz:
https://doaj.org/article/216fd572309c462f97d65eb4c453de26
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1005996 (2016)
Spatially controlled release of sister chromatid cohesion during progression through the meiotic divisions is of paramount importance for error-free chromosome segregation during meiosis. Cohesion is mediated by the cohesin protein complex and cleava
Externí odkaz:
https://doaj.org/article/f9bf70b46cb9410fb70909710f124163
Publikováno v:
PLoS Genetics, Vol 10, Iss 8, p e1004540 (2014)
Replicated sister chromatids are held in close association from the time of their synthesis until their separation during the next mitosis. This association is mediated by the ring-shaped cohesin complex that appears to embrace the sister chromatids.
Externí odkaz:
https://doaj.org/article/d60872bdc0fd4fbb8d2557312c1494e2
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107333 (2014)
The wing imaginal disc of Drosophila melanogaster is a prominent experimental system for research on control of cell growth, proliferation and death, as well as on pattern formation and morphogenesis during organogenesis. The precise genetic methodol
Externí odkaz:
https://doaj.org/article/2aa14af2097d4a6dab9d4ecb0448b561