Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Christian Eisen"'
Autor:
Thomas Höfner, Christian Eisen, Corinna Klein, Teresa Rigo-Watermeier, Stephan M. Goeppinger, Anna Jauch, Brigitte Schoell, Vanessa Vogel, Elisa Noll, Wilko Weichert, Irène Baccelli, Anja Schillert, Steve Wagner, Sascha Pahernik, Martin R. Sprick, Andreas Trumpp
Publikováno v:
Stem Cell Reports, Vol 4, Iss 3, Pp 503-518 (2015)
Methods to isolate and culture primary prostate epithelial stem/progenitor cells (PESCs) have proven difficult and ineffective. Here, we present a method to grow and expand both murine and human basal PESCs long term in serum- and feeder-free conditi
Externí odkaz:
https://doaj.org/article/33f168c807c34e308fe95cb2b77e3c7c
Autor:
Johannes Fredebohm, Michael Boettcher, Christian Eisen, Matthias M Gaida, Anette Heller, Shereen Keleg, Jörg Tost, Karin M Greulich-Bode, Agnes Hotz-Wagenblatt, Mark Lathrop, Nathalia A Giese, Jörg D Hoheisel
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48503 (2012)
Standard cancer cell lines do not model the intratumoural heterogeneity situation sufficiently. Clonal selection leads to a homogeneous population of cells by genetic drift. Heterogeneity of tumour cells, however, is particularly critical for therape
Externí odkaz:
https://doaj.org/article/9ea8793c424e46499de4989199b7c073
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Specific biological properties of those circulating cancer cells that are the origin of brain metastases (BM) are not well understood. Here, single circulating breast cancer cells were fate-tracked during all steps of the brain metastatic cascade in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4430eee691997f3dfbf7daec9f854e4b
https://doi.org/10.1158/1541-7786.c.6545246.v1
https://doi.org/10.1158/1541-7786.c.6545246.v1
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 3 shows PKH26 intensity and depth of the cell in relation to the successful establishment of a metastasis. Further, the brain metastatic cascade for PKH26 low (slow cycling) and PKH26 (high) (ultra slow cycling) cells is illustra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c4f4c45bd22576427dc0818fd7bd65
https://doi.org/10.1158/1541-7786.22526921.v1
https://doi.org/10.1158/1541-7786.22526921.v1
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 4 shows IVIS results.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca60a7e087ea9573afa334776c9cc81
https://doi.org/10.1158/1541-7786.22526918
https://doi.org/10.1158/1541-7786.22526918
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 6 shows NDRG1 expression in several cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ee072f60fd406802d4d3c4bea0a695
https://doi.org/10.1158/1541-7786.22526912
https://doi.org/10.1158/1541-7786.22526912
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 1 A-C shows loss of PKH26 over time. Supplementary Figure 1 D shows an additional example of a slow cycling cells with remaining PKH26 staining in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280b6e3b416bf36f12f9ce8d010ecff4
https://doi.org/10.1158/1541-7786.22526927
https://doi.org/10.1158/1541-7786.22526927
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 5 shows cell cycle analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0873bcbaa9a5d52e3d53398b97d8f2
https://doi.org/10.1158/1541-7786.22526915
https://doi.org/10.1158/1541-7786.22526915
Autor:
Frank Winkler, Wolfgang Wick, Matthias Preusser, Patricia S. Steeg, Andreas Trumpp, Miriam Ratliff, Carina M. Thome, Petra Rübmann, Lulu Huang, Miriam Gömmel, Gergely Solecki, Michael O. Breckwoldt, Natalia Becker, Felix Sahm, Zuszanna Bago-Horvath, Laura L. Michel, Frederic Marmé, Brunhilde Gril, Manuel Feinauer, Susanne Wünsche, Matthias Osswald, Tobias Kessler, Christian Eisen, Martin R. Sprick, Katharina Gunkel, Ayseguel Ilhan-Mutlu, Matthia A. Karreman, Yunxiang Liao, Anna. S. Berghoff
Supplementary Figure 2 cell index of PKH26 stained cells, the overlap of PKH26 loss and 2 other methods of cell division analysis as well as the reversion of a slow cycling cell population to a mixed cycling population.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dcd0bc72f8760f52cb915bfb184440
https://doi.org/10.1158/1541-7786.22526924
https://doi.org/10.1158/1541-7786.22526924
Autor:
Simon Lévy, Jürgen Herrler, Andrzej Liebert, Katharina Tkotz, Moritz S. Fabian, Christian Eisen, David Grodzki, Michael Uder, Arnd Dörfler, Moritz Zaiss, Armin M. Nagel
Publikováno v:
Magnetic resonance in medicineREFERENCES. 89(1)
To evaluate the benefits and challenges of dynamic parallel transmit (pTx) pulses for fat saturation (FS) and water-excitation (WE), in the context of CEST MRI."Universal" kWith a 25%-shorter pulse duration, pTx FS largely improved the FA homogeneity