Definition of metafounders based on population structure analysis

Autor: Christine Anglhuber, Christian Edel, Eduardo C. G. Pimentel, Reiner Emmerling, Kay-Uwe Götz, Georg Thaller

Publikováno v: Genetics Selection Evolution, Vol 56, Iss 1, Pp 1-18 (2024)

Abstract Background Limitations of the concept of identity by descent in the presence of stratification within a breeding population may lead to an incomplete formulation of the conventional numerator relationship matrix ( $$\mathbf{A}$$ A ). Combini

Externí odkaz: https://doaj.org/article/3d99c27620484d16910dea2322069fe3

Technical note: Methods for interim prediction of single-step breeding values for young animals

Autor: Christian Edel, Reiner Emmerling, E.C.G. Pimentel, Kay-Uwe Götz

Publikováno v: Journal of Dairy Science. 102:3266-3273

Single-step genomic evaluations have the advantage of simultaneously combining all pedigree, phenotypic, and genotypic information available. However, systems with a large number of genotyped animals have some computational challenges. In many genomi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f90d2291c0a0c9361d7d93e54ab1a3
https://doi.org/10.3168/jds.2018-15592

Short communication: The effect of genotyping cows to improve the reliability of genomic predictions for selection candidates

Autor: Christian Edel, Kay-Uwe Götz, Reiner Emmerling, L. Plieschke, E.C.G. Pimentel

Publikováno v: Journal of Dairy Science. 99:1999-2004

In this study we investigate the potential of enlarging the reference population for genomic prediction in dairy cattle by routinely genotyping a random sample of the first-crop daughters of every AI bull in the breeding program. We analyzed small nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1524dc9a7281628e8a6b0f730db04786
https://doi.org/10.3168/jds.2015-10246

Considering dominance in reduced single-step genomic evaluations

Autor: J. Ertl, Kay-Uwe Götz, E.C.G. Pimentel, Christian Edel, Reiner Emmerling

Publikováno v: Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie. 135(3)

Single-step models including dominance can be an enormous computational task and can even be prohibitive for practical application. In this study, we try to answer the question whether a reduced single-step model is able to estimate breeding values o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8fc63bafa9c56d72b90d22c60ad9497
https://pubmed.ncbi.nlm.nih.gov/29582470

Application of a Bayesian dominance model improves power in quantitative trait genome-wide association analysis

Autor: Ruedi Fries, Christian Edel, Jörn Bennewitz, Robin Wellmann, Theo H E Meuwissen

Publikováno v: Genetics, Selection, Evolution : GSE
Genetics Selection Evolution
Genetics Selection Evolution, BioMed Central, 2017, 49 (1), pp.7. ⟨10.1186/s12711-017-0284-7⟩

International audience; BackgroundMulti-marker methods, which fit all markers simultaneously, were originally tailored for genomic selection purposes, but have proven to be useful also in association analyses, especially the so-called BayesC Bayesian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f3770673b2d9021a915740ded707e3
http://europepmc.org/articles/PMC5237573