Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Christian Ebeling"'
Autor:
Tamara Raschka, Meemansa Sood, Bruce Schultz, Aybuge Altay, Christian Ebeling, Holger Fröhlich
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 2, p e1009894 (2023)
Modeling biological mechanisms is a key for disease understanding and drug-target identification. However, formulating quantitative models in the field of Alzheimer's Disease is challenged by a lack of detailed knowledge of relevant biochemical proce
Externí odkaz:
https://doaj.org/article/694483d60fd241c19ff4dc7fa87848d3
Autor:
Bruce Schultz, Andrea Zaliani, Christian Ebeling, Jeanette Reinshagen, Denisa Bojkova, Vanessa Lage-Rupprecht, Reagon Karki, Sören Lukassen, Yojana Gadiya, Neal G. Ravindra, Sayoni Das, Shounak Baksi, Daniel Domingo-Fernández, Manuel Lentzen, Mark Strivens, Tamara Raschka, Jindrich Cinatl, Lauren Nicole DeLong, Phil Gribbon, Gerd Geisslinger, Sandra Ciesek, David van Dijk, Steve Gardner, Alpha Tom Kodamullil, Holger Fröhlich, Manuel Peitsch, Marc Jacobs, Julia Hoeng, Roland Eils, Carsten Claussen, Martin Hofmann-Apitius
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The SARS-CoV-2 pandemic has challenged researchers at a global scale. The scientific community’s massive response has resulted in a flood of experiments, analyses, hypotheses, and publications, especially in the field of drug repurposing.
Externí odkaz:
https://doaj.org/article/18b0a7d14b824058a3306b2a9990465c
Autor:
Martin Hofmann-Apitius, Gordon Ball, Stephan Gebel, Shweta Bagewadi, Bernard de Bono, Reinhard Schneider, Matt Page, Alpha Tom Kodamullil, Erfan Younesi, Christian Ebeling, Jesper Tegnér, Luc Canard
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 12, Pp 29179-29206 (2015)
Since the decoding of the Human Genome, techniques from bioinformatics, statistics, and machine learning have been instrumental in uncovering patterns in increasing amounts and types of different data produced by technical profiling technologies appl
Externí odkaz:
https://doaj.org/article/c9828c177f1e45cab0bda7a82287c50c
Autor:
Femke N. G. van ’t Hof, Ynte M. Ruigrok, Cue Hyunkyu Lee, Stephan Ripke, Graig Anderson, Mariza de Andrade, Annette F. Baas, Jan D. Blankensteijn, Erwin P. Böttinger, Matthew J. Bown, Joseph Broderick, Philippe Bijlenga, David S. Carrell, Dana C. Crawford, David R. Crosslin, Christian Ebeling, Johan G. Eriksson, Myriam Fornage, Tatiana Foroud, Mikael von und zu Fraunberg, Christoph M. Friedrich, Emília I. Gaál, Omri Gottesman, Dong‐Chuan Guo, Seamus C. Harrison, Juha Hernesniemi, Albert Hofman, Ituro Inoue, Juha E. Jääskeläinen, Gregory T. Jones, Lambertus A. L. M. Kiemeney, Riku Kivisaari, Nerissa Ko, Seppo Koskinen, Michiaki Kubo, Iftikhar J. Kullo, Helena Kuivaniemi, Mitja I. Kurki, Aki Laakso, Dongbing Lai, Suzanne M. Leal, Hanna Lehto, Scott A. LeMaire, Siew‐Kee Low, Jennifer Malinowski, Catherine A. McCarty, Dianna M. Milewicz, Thomas H. Mosley, Yusuke Nakamura, Hirofumi Nakaoka, Mika Niemelä, Jennifer Pacheco, Peggy L. Peissig, Joanna Pera, Laura Rasmussen‐Torvik, Marylyn D. Ritchie, Fernando Rivadeneira, Andre M. van Rij, Regie Lyn P. Santos‐Cortez, Athanasios Saratzis, Agnieszka Slowik, Atsushi Takahashi, Gerard Tromp, André G. Uitterlinden, Shefali S. Verma, Sita H. Vermeulen, Gao T. Wang, Buhm Han, Gabriël J. E. Rinkel, Paul I. W. de Bakker, Ana Verissimo, Benjamin J. Wright, Suzannah Bumpstead, Solveig Gretarsdottir, Stephen A. Badger, Anne H. Child, Rachel E. Clough, Gillian Cockerill, Hany Hafez, D. Julian A. Scott, Simon Futers, Soroush Sohrabi, Alberto Smith, Matthew M. Thompson, Frank M. van Bockxmeer, Stefan E. Matthiasson, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Joep A. W. Teijink, Cisca Wijmenga, Jacqueline de Graaf, Lambertus A. Kiemeney, Jutta Palmen, Andrew J. Smith, Jes S. Lindholt, Declan T. Bradley, Matthew Waltham, Sarah Edkins, Rhian Gwilliam, Sarah E. Hunt, Simon Potter, Jonathan Golledge, Per Eriksson, Paul E. Norman, Janet T. Powell, Kari Stefansson, John R. Thompson, Steve E. Humphries, Robert D. Sayers, Panos Deloukas, Nilesh J. Samani, L. Victoria Phillip, Geraldine B. Hill, Michael J. A. Williams, Ian A. Thomson, Jo Krysa, Gerard T. Wilkins, Tony R. Merriman, Thodor M. Vasudevan, David R. Lewis, Ross D. Blair, Andrew A. Hill
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 7 (2016)
BackgroundIntracranial aneurysms (IAs), abdominal aortic aneurysms (AAAs), and thoracic aortic aneurysms (TAAs) all have a familial predisposition. Given that aneurysm types are known to co‐occur, we hypothesized that there may be shared genetic ri
Externí odkaz:
https://doaj.org/article/2acb672bf4a74a25b54ac4cd784f7c16
Autor:
Christian Ebeling
Der Essay zur Natur der Sprache entwickelt eine neue und unvoreingenommene Sicht auf Sprache, die die wichtigsten Sprachbegriffe zunächst dekonstruiert, um daraufhin nach möglichen Rekonstruktionen zu suchen. Dabei werden nicht nur die aktuellen Di
Autor:
A. Podstawka, L.C. Reimer, Christian Ebeling, Julia Koblitz, Joaquim Sardà Carbasse, Jörg Overmann
Publikováno v:
Nucleic Acids Research
The bacterial metadatabase BacDive (https://bacdive.dsmz.de) has developed into a leading database for standardized prokaryotic data on strain level. With its current release (07/2021) the database offers information for 82 892 bacterial and archaeal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c8938b7876ec29d0f1c2e71574a0fc
http://europepmc.org/articles/PMC8728306
http://europepmc.org/articles/PMC8728306
Autor:
Tamara Raschka, Meemansa Sood, Bruce Schultz, Aybuge Altay, Christian Ebeling, Holger Fröhlich
Modeling biological mechanisms is a key for disease understanding and drug-target identification. However, formulating quantitative models in the field of Alzheimer’s Disease is challenged by a lack of detailed knowledge of relevant biochemical pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008bd9ea3d0bec16652366e2ef533194
https://doi.org/10.1101/2022.02.04.479087
https://doi.org/10.1101/2022.02.04.479087
Deletion of Alzheimer's disease-associated CD33 results in an inflammatory human microglia phenotype
Autor:
Veit Hornung, Harald Neumann, Oliver Brüstle, Ichiro Nozaki, Christian Ebeling, Tamara Raschka, Mona Mathews, Jannis Wißfeld
Publikováno v:
Glia
Genome‐wide association studies demonstrated that polymorphisms in the CD33/sialic acid‐binding immunoglobulin‐like lectin 3 gene are associated with late‐onset Alzheimer's disease (AD). CD33 is expressed on myeloid immune cells and mediates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3bac22f255b9db120ee18124320bbed
https://zenodo.org/record/4771070
https://zenodo.org/record/4771070
Autor:
Sayoni Das, Daniel Domingo-Fernández, Jindrich Cinatl, Manuel C. Peitsch, Sandra Ciesek, Martin Hofmann-Apitius, Shounak Baksi, Gerd Geisslinger, Bruce T. Schultz, P. Gribbon, Tamara Raschka, Julia Hoeng, Marc Jacobs, David van Dijk, Christian Ebeling, Manuel Lentzen, Roland Eils, Mark Strivens, Steve Gardner, Holger Fröhlich, Alpha Tom Kodamullil, Yojana Gadiya, Neal G. Ravindra, Jeanette Reinshagen, Vanessa Lage-Rupprecht, Carsten Claussen, Reagon Karki, Denisa Bojkova, Sören Lukassen, Andrea Zaliani, Lauren Nicole DeLong
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
The SARS-CoV-2 pandemic has challenged researchers at a global scale. The scientific community’s massive response has resulted in a flood of experiments, analyses, hypotheses, and publications, especially in the field of drug repurposing. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20377f751b3385b2b897585b58254840
Autor:
Alpha Tom Kodamullil, Tamara Raschka, Martin Hofmann-Apitius, Bruce T. Schultz, Reagon Karki, Daniel Domingo-Fernández, Shounak Baksi, Yojana Gadiya, Christian Ebeling
Publikováno v:
Bioinformatics
Bioinformatics 37(9), 1332-1334 (2021). doi:10.1093/bioinformatics/btaa834
Published by Oxford Univ. Press, Oxford
Published by Oxford Univ. Press, Oxford
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508ecc3689a957b7e367dee375c0a6c9