Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Christian E. Pedersen"'
Pain induces adaptations in ventral tegmental area dopamine neurons to drive anhedonia-like behavior
Autor:
Hye Jean Yoon, Meaghan C. Creed, Jose A. Morón, Veronica A. Alvarez, Christian E. Pedersen, Yvan M. Vachez, Kavitha Abiraman, Nicolas Massaly, Michael R. Bruchas, Brian Ruyle, Jeniffer J. Garcia, Caitlin A. Murphy, Jung Hoon Shin, Tamara Markovic
Publikováno v:
Nat Neurosci
The persistence of negative affect in pain leads to co-morbid symptoms such as anhedonia and depression-major health issues in the United States. The neuronal circuitry and contribution of specific cellular populations underlying these behavioral ada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc74d9a34de0e6d9bf3111bd238f293
https://doi.org/10.1038/s41593-021-00924-3
https://doi.org/10.1038/s41593-021-00924-3
Autor:
Christian E. Pedersen, Daniel C. Castro, Madelyn M. Gray, Zhe C. Zhou, Sean C. Piantadosi, Raajaram Gowrishankar, Shane A. Kan, Patrick J. Murphy, Patrick R. O’Neill, Michael R. Bruchas
Medial nucleus accumbens shell (mNAcSh) is a critical brain region for driving motivated behaviors. Despite this well-established role, the underlying reward processing of individual neurons, circuits and cell-types within mNAcSh remains largely unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1cad7c204d9b5d84d0624e6b9a95c9e
https://doi.org/10.1101/2022.09.18.508426
https://doi.org/10.1101/2022.09.18.508426
Autor:
Miao Jing, Raajaram Gowrishankar, Abigail J. Elerding, Ream Al-Hasani, Julia C. Lemos, Christian E. Pedersen, Veronica A. Alvarez, Gavin P. Schmitz, Yulong Li, Sophie J. Renaud, David J. Marcus, Michael R. Bruchas, Sofia E. Shirley, Taylor Hobbs
Publikováno v:
Nature Neuroscience. 24:1414-1428
The long-range GABAergic input from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) is relatively understudied, and therefore its role in reward processing has remained unknown. In the present study, we show, in both male and female m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::289d375de86ec4b05375647e1266ce2f
https://doi.org/10.1038/s41593-021-00898-2
https://doi.org/10.1038/s41593-021-00898-2
Autor:
Sean C Piantadosi, Zhe Charles Zhou, Carina Pizzano, Christian E Pedersen, Tammy K Nguyen, Sarah Thai, Garret D Stuber, Michael R Bruchas
SummaryThe basolateral amygdala (BLA) is an evolutionarily conserved brain region, well known for valence processing. Despite this central role, the relationship between activity of BLA neuronal ensembles in response to appetitive and aversive stimul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f86375448a113fcc31d1da73d315ce9d
https://doi.org/10.1101/2022.07.11.499499
https://doi.org/10.1101/2022.07.11.499499
Autor:
Daniel C. Castro, Mark A. Rossi, Sean C. Piantadosi, Larry S. Zweifel, Anthony Guglin, Jose A. Morón, Michael R. Bruchas, Avery C. Hunker, Eric T. Zhang, Garret D. Stuber, Corinna S. Oswell, Christian E. Pedersen
Publikováno v:
Nature
µ-Opioid peptide receptor (MOPR) stimulation alters respiration, analgesia and reward behaviour, and can induce substance abuse and overdose1–3. Despite its evident importance, the endogenous mechanisms for MOPR regulation of consummatory behaviou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e669658a00079159caa5cbf2dfcc4f4
https://europepmc.org/articles/PMC8858443/
https://europepmc.org/articles/PMC8858443/
Autor:
Michael R. Bruchas, Gary E. Grajales-Reyes, Jose G. Grajales-Reyes, Eric Tycksen, Christian E. Pedersen, Julian N Sackey, Vijay K. Samineni, Sienna B Sewell, Edem S Ankudey, Robert W. Gereau, Bryan A. Copits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59c9add4e1a6bf69446e46290f356c27
https://doi.org/10.7554/elife.68130.sa2
https://doi.org/10.7554/elife.68130.sa2
Autor:
Robert W. Gereau, Bryan A. Copits, Jose G. Grajales-Reyes, Michael R. Bruchas, Vijay K. Samineni, Gary E. Grajales-Reyes, Edem S Ankudey, Sienna B Sewell, Julian N Sackey, Christian E. Pedersen, Eric Tycksen
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Itch is an unpleasant sensation that elicits robust scratching and aversive experience. However, the identity of the cells and neural circuits that organize this information remains elusive. Here, we show the necessity and sufficiency of chloroquine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58b02dc5be757e38f1b05719d024b09
https://elifesciences.org/articles/68130
https://elifesciences.org/articles/68130
Autor:
Robert W. Gereau, Jose G. Grajales-Reyes, Bryan A. Copits, Sienna B Sewell, Eric Tycksen, Christian E. Pedersen, Michael R. Bruchas, Gary E. Grajales-Reyes, Julian N Sackey, Vijay K. Samineni, Edem S Ankudey
Itch is an unpleasant sensation that elicits robust scratching and active avoidance. However, the identity of the cells and neural circuits that organize this information remains elusive. Here we show the necessity and sufficiency of itch-activated n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18883f39761ef21d4ced216631ec55b8
https://doi.org/10.1101/2021.02.18.431884
https://doi.org/10.1101/2021.02.18.431884
Autor:
Jose A. Morón, Eric T. Zhang, Oswell Cs, Guglin A, Garret D. Stuber, Sean C. Piantadosi, Michael R. Bruchas, Christian E. Pedersen, Larry S. Zweifel, Avery C. Hunker, Mark A. Rossi, Daniel C. Castro
Mu-opioid peptide receptor (MOPR) stimulation alters respiration, analgesia, and reward behavior, and can induce addiction and drug overdose. Despite its evident importance, the endogenous mechanisms for MOPR regulation of appetitive behavior have re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e45bc9dd8a6f296c2b14fcf26f6ec7e
https://doi.org/10.1101/2021.02.10.430657
https://doi.org/10.1101/2021.02.10.430657
Autor:
Karl J. Kaiyala, Jarrad M. Scarlett, Michael W. Schwartz, Chelsea L. Faber, Vincent Damian, Gregory J. Morton, Sarah A Larsen, Megan A. Tran, Christian E. Pedersen, Bao Anh Phan, Richard D. Palmiter, Kayoko Ogimoto, Jennifer D. Deem, Jarrell T. Nelson, Michael R. Bruchas
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
To maintain energy homeostasis during cold exposure, the increased energy demands of thermogenesis must be counterbalanced by increased energy intake. To investigate the neurobiological mechanisms underlying this cold-induced hyperphagia, we asked wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fbbbe35e2b9bfc49b3760d4af266cb
https://elifesciences.org/articles/58764
https://elifesciences.org/articles/58764