Zobrazeno 1 - 10
of 1 193
pro vyhledávání: '"Christian E. Elger"'
Autor:
Lena‐Luise Becker, Konstantin L. Makridis, Angela T. Abad‐Perez, Ulrich‐Wilhelm Thomale, Anna Tietze, Christian E. Elger, Denise Horn, Angela M. Kaindl
Publikováno v:
Epilepsia Open, Vol 9, Iss 2, Pp 800-807 (2024)
Abstract Genetic variants in relevant genes coexisting with MRI lesions in children with drug‐resistant epilepsy (DRE) can negatively influence epilepsy surgery outcomes. Still, presurgical evaluation does not include genetic diagnostics routinely.
Externí odkaz:
https://doaj.org/article/dd9e53ab3bb1429f9267b4b91901b431
Autor:
Attila Rácz, Philipp Müller, Albert Becker, Nico Hoffmann, Theodor Rüber, Valeri Borger, Hartmut Vatter, Rainer Surges, Christian E. Elger
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
PurposeNeuroglial tumors are frequently associated with pharmacorefractory epilepsies. However, comprehensive knowledge about long-term outcomes after epilepsy surgery and the main prognostic factors for outcome is still limited. We sought to evaluat
Externí odkaz:
https://doaj.org/article/1704b3e4143142a89ab7451ec8d12c1b
Autor:
Konstantin L. Makridis, Kerstin Alexandra Klotz, Georgia Ramantani, Lena‐Luise Becker, Victoria San Antonio‐Arce, Steffen Syrbe, Kathrin Wagner, Mukesch Johannes Shah, Ulrich‐Wilhelm Thomale, Anna Tietze, Christian E. Elger, Ingo Borggraefe, Angela M. Kaindl
Publikováno v:
Epilepsia Open, Vol 8, Iss 3, Pp 1182-1189 (2023)
Abstract Although epilepsy surgery is the only curative therapeutic approach for lesional drug‐resistant epilepsy (DRE), there is reluctance to operate on infants due to a fear of complications. A recent meta‐analysis showed that epilepsy surgery
Externí odkaz:
https://doaj.org/article/042924e4e8514d13ab7940ff51d22b24
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Status epilepticus is one of the most common life-threatening neurological emergencies in childhood with the highest incidence in the first 5 years of life and high mortality and morbidity rates. Although it is known that a delayed treatment and a pr
Externí odkaz:
https://doaj.org/article/ad2dbcf19a3940948ccd64a11b05f303
Autor:
Andre Dik, Guido Widman, Andreas Schulte‐Mecklenbeck, Juri‐Alexander Witt, Julika Pitsch, Kristin S. Golombeck, Jan Wagner, Marco Gallus, Christine Strippel, Niels Hansen, Constanze Mönig, Saskia Räuber, Heinz Wiendl, Christian E. Elger, Rainer Surges, Sven G. Meuth, Christoph Helmstaedter, Catharina C. Gross, Albert J. Becker, Nico Melzer
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 12, Pp 2289-2301 (2021)
Abstract Objective Direct pathogenic effects of autoantibodies to the 65 kDa isoform of glutamic acid decarboxylase (GAD65) in autoimmune limbic encephalitis (LE) have been questioned due to its intracellular localization. We therefore hypothesized a
Externí odkaz:
https://doaj.org/article/9d05e3b0b880426b8a6d71870f8730c4
Autor:
Marcel Bausch, Johannes Niediek, Thomas P. Reber, Sina Mackay, Jan Boström, Christian E. Elger, Florian Mormann
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
It is unclear how distinct concepts are processed in the brain. Here, the authors recorded from concept cells in human subjects with epilepsy and found that a subset of concept cells responded to non-preferred concepts if those non-preferred concepts
Externí odkaz:
https://doaj.org/article/56f3480a3dda4892a4836bddb2c782a0
Autor:
Amirhossein Jahanbekam, Jan Baumann, Robert D. Nass, Christian Bauckhage, Holger Hill, Christian E. Elger, Rainer Surges
Publikováno v:
Epilepsia Open, Vol 6, Iss 3, Pp 597-606 (2021)
Abstract Objective To identify non‐EEG‐based signals and algorithms for detection of motor and non‐motor seizures in people lying in bed during video‐EEG (VEEG) monitoring and to test whether these algorithms work in freely moving people duri
Externí odkaz:
https://doaj.org/article/b04828eebcd64801919423816563b2d0
Autor:
Conrad C. Prillwitz, Bastian David, Gottfried Schlaug, Thomas Deller, Johannes Schramm, Robert Lindenberg, Elke Hattingen, Bernd Weber, Rainer Surges, Christian E. Elger, Theodor Rüber
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 9, Pp 1796-1808 (2021)
Abstract Objective Using multimodal imaging, we tested the hypothesis that patients after hemispherotomy recruit non‐primary motor areas and non‐pyramidal descending motor fibers to restore motor function of the impaired limb. Methods Functional
Externí odkaz:
https://doaj.org/article/248cf770f9dd43a0b0802f6650e038fe
Autor:
Attila Rácz, Chiara A. Hummel, Albert Becker, Christoph Helmstaedter, Fabiane Schuch, Tobias Baumgartner, Randi von Wrede, Valeri Borger, László Solymosi, Rainer Surges, Christian E. Elger
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
PurposeLimbic encephalitis is an increasingly recognized cause of medial temporal lobe epilepsy (mTLE) and associated cognitive deficits, potentially resulting in hippocampal sclerosis (HS). For several reasons, these patients usually do not undergo
Externí odkaz:
https://doaj.org/article/cf55362252a14755a409c26f1387a87d
Autor:
Bastian David, Jasmine Eberle, Daniel Delev, Jennifer Gaubatz, Conrad C. Prillwitz, Jan Wagner, Jan-Christoph Schoene-Bake, Guido Luechters, Alexander Radbruch, Bettina Wabbels, Johannes Schramm, Bernd Weber, Rainer Surges, Christian E. Elger, Theodor Rüber
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Selective amygdalohippocampectomy is an effective treatment for patients with therapy-refractory temporal lobe epilepsy but may cause visual field defect (VFD). Here, we aimed to describe tissue-specific pre- and postoperative imaging correl
Externí odkaz:
https://doaj.org/article/98b3ccc5d64e4e48ac29f980874fefa7