Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christian Dokomajilar"'
Autor:
Lisa M. Bebell, Grant Dorsey, Wilson Kambale, Philip J. Rosenthal, Christian Dokomajilar, Heidi Hopkins
Publikováno v:
The Journal of Infectious Diseases. 197:510-518
In Africa fever is often treated presumptively as malaria resulting in misdiagnosis and the overuse of antimalarial drugs. Rapid diagnostic tests (RDTs) for malaria may allow improved fever management. We compared RDTs based on histidine-rich protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e816f2f74429bcd61295214fa6be1063
https://doi.org/10.1086/526502
https://doi.org/10.1086/526502
Autor:
Issaka Zongo, Christian Dokomajilar, Noel Rouamba, Jean-Bosco Ouédraogo, Halidou Tinto, Grant Dorsey, Philip J. Rosenthal, Robert T. Guiguemdé
Publikováno v:
The Lancet. 369:491-498
Summary Background Artemisinin-based combination regimens are widely advocated for malarial treatment, but other effective regimens might be cheaper and more readily available. Our aim was to compare the risk of recurrent parasitaemia in patients giv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d279c6567fd8ac8efe10b0c56485a55b
https://doi.org/10.1016/s0140-6736(07)60236-0
https://doi.org/10.1016/s0140-6736(07)60236-0
Autor:
Philip J. Rosenthal, Elaine J. Carlson, Jonathan M. Woo, Grant Dorsey, Bryan Greenhouse, Christian Dokomajilar, Alissa Myrick
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 75:836-842
Genotyping methods for Plasmodium falciparum drug efficacy trials have not been standardized and may fail to accurately distinguish recrudescence from new infection, especially in high transmission areas where polyclonal infections are common. We dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6641179f7f9d345a879ad0d08e24192
https://doi.org/10.4269/ajtmh.2006.75.836
https://doi.org/10.4269/ajtmh.2006.75.836
Autor:
Sarah G. Staedke, Philip J. Rosenthal, Moses R. Kamya, Christian Dokomajilar, Moses Kiggundu, Grant Dorsey
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 71:758-763
Antimalarial resistance to sulfadoxine-pyrimethamine (SP) is mediated by mutations in the dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes. However, the relative importance of different mutations is incompletely understood and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37592d3792a01deeda3fefbfcda0c78d
https://doi.org/10.4269/ajtmh.2004.71.758
https://doi.org/10.4269/ajtmh.2004.71.758
Publikováno v:
Antimicrobial Agents and Chemotherapy. 51:3023-3025
Key parasite polymorphisms were assessed in subjects treated for malaria with artesunate-amodiaquine in Tororo, Uganda. For pfcrt , all of the isolates tested had the CVIET haplotype. For pfmdr1 , 86Y and 1246Y were common at baseline and their preva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0934d1c7991106627b913b667ed3a2eb
https://doi.org/10.1128/aac.00012-07
https://doi.org/10.1128/aac.00012-07
Publikováno v:
Antimicrobial Agents and Chemotherapy. 50:1893-1895
Polymorphisms in the Plasmodium falciparum pfmdr1 gene were assayed in pretreatment samples and in samples from patients reinfected following therapy with artemether-lumefantrine. The pfmdr1 alleles 86N, 184F, and 1246D significantly increased in pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8e18682e6ac96f1a72803e1604e6c1
https://doi.org/10.1128/aac.50.5.1893-1895.2006
https://doi.org/10.1128/aac.50.5.1893-1895.2006
Autor:
Anyirékun Fabrice Somé, Jean-Bosco Ouédraogo, Bryan Greenhouse, Noel Rouamba, Issaka Zongo, Yves Y. Séré, Christian Dokomajilar, Philip J. Rosenthal
Publikováno v:
Antimicrobial agents and chemotherapy. 54(5)
Artemether-lumefantrine (AL), dihydroartemisinin-piperaquine (DP), and amodiaquine-sulfadoxine-pyrimethamine (AQ-SP) offer excellent antimalarial efficacy but may select for parasite polymorphisms that decrease drug sensitivity. We evaluated the sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faff28f5e9345d5c4ca9399e9a768e61
https://pubmed.ncbi.nlm.nih.gov/20231394
https://pubmed.ncbi.nlm.nih.gov/20231394
Publikováno v:
Antimicrobial agents and chemotherapy. 51(9)
Antimalarial clinical trials use genotyping techniques to distinguish new infection from recrudescence. In areas of high transmission, the accuracy of genotyping may be compromised due to the high number of infecting parasite strains. We compared the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41ff974fd95eeaf558bf5f7d275d9b6
https://pubmed.ncbi.nlm.nih.gov/17591848
https://pubmed.ncbi.nlm.nih.gov/17591848
Autor:
Philip J. Rosenthal, Issaka Zongo, Christian Dokomajilar, Grant Dorsey, Jean-Bosco Ouédraogo, Yves Y. Séré, Noel Rouamba
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 45(11)
BACKGROUND: Combination antimalarial therapy is advocated to improve treatment efficacy and limit selection of drug-resistant parasites. We compared the efficacies of 3 combination regimens in Bobo-Dioulasso, Burkina Faso: amodiaquine plus sulfadoxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7600ed2bce7ab54e5d12864fa09cf8bb
https://pubmed.ncbi.nlm.nih.gov/17990228
https://pubmed.ncbi.nlm.nih.gov/17990228
Autor:
Bryan, Greenhouse, Alissa, Myrick, Christian, Dokomajilar, Jonathan M, Woo, Elaine J, Carlson, Philip J, Rosenthal, Grant, Dorsey
Publikováno v:
The American journal of tropical medicine and hygiene. 75(5)
Genotyping methods for Plasmodium falciparum drug efficacy trials have not been standardized and may fail to accurately distinguish recrudescence from new infection, especially in high transmission areas where polyclonal infections are common. We dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05a15ee1ec8346165cc46b696beeb191
https://pubmed.ncbi.nlm.nih.gov/17123974
https://pubmed.ncbi.nlm.nih.gov/17123974