Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Christian Demers"'
Autor:
Vincent Pichette, François A. Leblond, Denis Ouimet, Jean-Luc Petit, Alain Bonnardeaux, Marielle Gascon-Barré, Josée Michaud, Judith Naud, Christian Demers
Publikováno v:
Journal of the American Society of Nephrology. 21:1488-1497
Calcidiol insufficiency is highly prevalent in chronic kidney disease (CKD), but the reasons for this are incompletely understood. CKD associates with a decrease in liver cytochrome P450 (CYP450) enzymes, and specific CYP450 isoforms mediate vitamin
Publikováno v:
Journal of Bone and Mineral Research. 10:1148-1157
The 25(OH)D 3 /1,25 (OH) 2 D 3 24-hydroxylase (24-hydroxylase) displays an induction profile responsive to vitamin D (D) abundance and is hence only observed in normal extracellular Ca 2+ concentrations. However, the participation of Ca 2+ in the exp
Autor:
Marielle Gascon-Barré, Louise Rousseau, Jean-Luc Petit, Richard J. Zahradnik, Jean-Hugues Brossard, E.F. Nemeth, Pierre D’Amour, M. Usatii, Christian Demers, Jeffrey R. Lavigne
Publikováno v:
Kidney International. 72(11):1330-1335
Carboxyl (C)-terminal fragments of parathyroid hormone (PTH) oppose the calcemic, phosphaturic, and bone-resorbing effects of active hormone. To study the action of these fragments on 1,25(OH) 2 D (1,25-dihydroxyvitamin D) synthesis, we infused parat
Autor:
Marielle Gascon-Barré, S. Zalzal, Stéphane Néron, Antonio Nanci, Christian Demers, Ali Mirshahi
Publikováno v:
Hepatology. 37:1034-1042
The liver is generally considered negative for the vitamin D nuclear receptor (VDRn), even though several studies have shown significant effects of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) on liver cell physiology. The low abundance of VDRn in the live
Autor:
Edgard Delvin, Daniel Ménard, Catherine Theodoropoulos, Marielle Gascon-Barré, Christian Demers
Publikováno v:
Clinical Endocrinology. 58:489-499
BACKGROUND AND AIMS The human fetal jejunum has been shown to harbour the vitamin D 3 (D 3 ) nuclear receptor (VDR n ) and to be responsive to calcitriol/ 1,25-dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ] through modulation of proliferation and differentia
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 281:E315-E325
The vitamin D3-25-hydroxylase CYP27A is located predominantly in liver, but its expression is also detected in extrahepatic tissues. Our aim was to evaluate the regulation of CYP27A by vitamin D3(D3) or its metabolites in rat duodena. Vitamin D-deple
Publikováno v:
Endocrinology. 133:780-792
1,25-Dihydroxyvitamin D3 [1,25-(OH)2D3] is known to influence cell proliferation/maturation, whereas epidermal growth factor (EGF) is a potent stimulant of proliferation. Recently, hypocalcemia of vitamin D (D) deficiency was shown to significantly p
Publikováno v:
Gene. 341
Biogenic amines exert various physiological effects in cnidarians, but the receptors involved in these responses are not known. We have cloned a novel G protein-coupled receptor cDNA from an anthozoan, the sea pansy Renilla koellikeri, that shows hom
Autor:
Catherine, Theodoropoulos, Christian, Demers, Edgard, Delvin, Daniel, Ménard, Marielle, Gascon-Barré
Publikováno v:
Clinical endocrinology. 58(4)
The human fetal jejunum has been shown to harbour the vitamin D3 (D3) nuclear receptor (VDRn) and to be responsive to calcitriol/1,25-dihydroxyvitamin D3[1,25(OH)2D3] through modulation of proliferation and differentiation processes. The aim of the s
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 284(1)
CYP27A is considered the main vitamin D3(D3)-25 hydroxylase in humans. Our purpose was to evaluate the effect of the D3nutritional and hormonal status on hepatic CYP27A mRNA, cellular distribution, transcription rate, and enzyme activity. Studies wer