Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christian D. Peikert"'
Autor:
Marcel Morgenstern, Sebastian B. Stiller, Philipp Lübbert, Christian D. Peikert, Stefan Dannenmaier, Friedel Drepper, Uri Weill, Philipp Höß, Reinhild Feuerstein, Michael Gebert, Maria Bohnert, Martin van der Laan, Maya Schuldiner, Conny Schütze, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid
Publikováno v:
Cell Reports, Vol 19, Iss 13, Pp 2836-2852 (2017)
Mitochondria perform central functions in cellular bioenergetics, metabolism, and signaling, and their dysfunction has been linked to numerous diseases. The available studies cover only part of the mitochondrial proteome, and a separation of core mit
Externí odkaz:
https://doaj.org/article/afe2beb6dfb24cbab29ea223b1e61717
Autor:
Christian D. Peikert, Jan Mani, Marcel Morgenstern, Sandro Käser, Bettina Knapp, Christoph Wenger, Anke Harsman, Silke Oeljeklaus, André Schneider, Bettina Warscheid
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Knowing the specific protein content of individual organelles is necessary for an integrated understanding of cellular physiology. Here the authors describe a mass spectrometry-based approach to identify the substrates of distinct protein import path
Externí odkaz:
https://doaj.org/article/bf7073abf7dd409ea6d6cecc74034615
Autor:
Anna L. Fricke, Wignand W. D. Mühlhäuser, Lena Reimann, Johannes P. Zimmermann, Christa Reichenbach, Bettina Knapp, Christian D. Peikert, Alexander M. Heberle, Erik Faessler, Sascha Schäuble, Udo Hahn, Kathrin Thedieck, Gerald Radziwill, Bettina Warscheid
Publikováno v:
Journal of Proteome Research, 22(3), 768-789. NLM (Medline)
Phosphorylation-dependent signal transduction plays an important role in regulating the functions and fate of skeletal muscle cells. Central players in the phospho-signaling network are the protein kinases AKT, S6K, and RSK as part of the PI3K-AKT-mT
Autor:
Lena Reimann, Friedel Drepper, Sascha Schäuble, Christian D. Peikert, Wignand W. D. Mühlhäuser, Dieter O. Fürst, Yvonne Leber, Peter F.M. van der Ven, Clemens Kreutz, Heike Wiese, Keerthika Lohanadan, Anja N. Schwäble, Christa Reichenbach, Erik Faessler, Bettina Knapp, Kristina Djinović-Carugo, Bettina Warscheid, Gerald Radziwill, Anna L. Fricke, Udo Hahn, Martin Puchinger
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-19 (2020)
Communications Biology
Communications Biology
The PI3K/Akt pathway promotes skeletal muscle growth and myogenic differentiation. Although its importance in skeletal muscle biology is well documented, many of its substrates remain to be identified. We here studied PI3K/Akt signaling in contractin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251bee94ac9e94781665506b4a5825b5
https://doi.org/10.1038/s42003-020-0982-5
https://doi.org/10.1038/s42003-020-0982-5
Autor:
Ida Suppanz, Marcel Morgenstern, Laura Melchionda, Conny Steiert, Sven Dennerlein, Nils Wiedemann, Bettina Warscheid, Nataliia Naumenko, Oliver Alka, Cinzia Klemm, Christopher Eickhorst, Sebastian B. Stiller, Silke Oeljeklaus, Christian D. Peikert, Claudine Kraft, Alexander Schendzielorz, Wignand W. D. Mühlhäuser, Caroline Lindau, Philipp Lübbert, Nikolaus Pfanner, Stefan Dannenmaier, Bettina Knapp, Jakob D. Busch, Riccardo Galbusera, Mariya Licheva, Friedel Drepper, Vera Kozjak-Pavlovic, Michael T. Ryan, Ralf M. Zerbes
Publikováno v:
Cell Metabolism
Summary Mitochondria are key organelles for cellular energetics, metabolism, signaling, and quality control and have been linked to various diseases. Different views exist on the composition of the human mitochondrial proteome. We classified >8,000 p
Autor:
Richard Wagner, Jan Mani, Moritz Niemann, Silke Oeljeklaus, André Schneider, Christian D. Peikert, Anke Judith Harsman, Bettina Warscheid
Publikováno v:
Proceedings of the National Academy of Sciences
Mitochondrial tRNA import is widespread, but the mechanism by which tRNAs are imported remains largely unknown. The mitochondrion of the parasitic protozoan Trypanosoma brucei lacks tRNA genes, and thus imports all tRNAs from the cytosol. Here we sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f29c458fdcf1a8b2f321f36c7f0d51d
Autor:
Yvonne Leber, Anne Rohland, Bettina Warscheid, Bettina Knapp, Christian D. Peikert, Heike Wiese, Peter F.M. van der Ven, Lena Reimann, Friedel Drepper, Gerald Radziwill, Anna L. Fricke, Dieter O. Fürst, Anja N. Schwäble
Publikováno v:
Molecularcellular proteomics : MCP. 16(3)
The Z-disc is a protein-rich structure critically important for the development and integrity of myofibrils, which are the contractile organelles of cross-striated muscle cells. We here used mouse C2C12 myoblast, which were differentiated into myotub
Autor:
Christian D. Peikert, André Schneider, Anke Judith Harsman, Christoph Wenger, Bettina Warscheid, Marcel Morgenstern, Bettina Knapp, Silke Oeljeklaus, Jan Mani, Sandro Käser
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Peikert, Christian D.; Mani, Jan; Morgenstern, Marcel; Käser, Sandro; Knapp, Bettina; Wenger, Christoph; Harsman, Anke Judith; Oeljeklaus, Silke; Schneider, André; Warscheid, Bettina (2017). Charting organellar importomes by quantitative mass spectrometry. Nature communications, 8(1), p. 15272. Nature Publishing Group 10.1038/ncomms15272
Nature Communications
Peikert, Christian D.; Mani, Jan; Morgenstern, Marcel; Käser, Sandro; Knapp, Bettina; Wenger, Christoph; Harsman, Anke Judith; Oeljeklaus, Silke; Schneider, André; Warscheid, Bettina (2017). Charting organellar importomes by quantitative mass spectrometry. Nature communications, 8(1), p. 15272. Nature Publishing Group 10.1038/ncomms15272
Nature Communications
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein translocation machineries. Analysing whether a protein is transported into an organelle is largely restricted to single constituents. This renders knowled