Zobrazeno 1 - 10
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pro vyhledávání: '"Christian D. Mohr"'
Autor:
Christian D. Mohr, Mladen Tomich
Publikováno v:
Journal of Bacteriology. 186:3826-3836
Cable pili are peritrichous organelles expressed by certain strains of Burkholderia cenocepacia , believed to facilitate colonization of the lower respiratory tract in cystic fibrosis patients. The B. cenocepacia cblBACDS operon encodes the structura
Autor:
Mladen Tomich, Christian D. Mohr
Publikováno v:
Journal of Bacteriology. 186:1009-1020
Burkholderia cenocepacia is an important member of the Burkholderia cepacia complex, a group of closely related bacteria that inhabits a wide variety of environmental niches in nature and that also colonizes the lungs of compromised humans. Certain s
Publikováno v:
Infection and Immunity. 70:1799-1806
Burkholderia cepacia is an important opportunistic human pathogen that affects immunocompromised individuals, particularly cystic fibrosis (CF) patients. Colonization of the lungs of a CF patient by B. cepacia can lead not only to a decline in respir
A Membrane-Associated Protein, FliX, Is Required for an Early Step in Caulobacter Flagellar Assembly
Publikováno v:
Journal of Bacteriology. 180:2175-2185
The ordered assembly of the Caulobacter crescentus flagellum is accomplished in part through the organization of the flagellar structural genes in a regulatory hierarachy of four classes. Class II genes are the earliest to be expressed and are activa
Publikováno v:
Journal of Bacteriology. 178:675-682
The P- and L-rings are structural components of the flagellar basal body that are positioned in the periplasmic space and outer membrane, respectively. In order to explore the mechanism of P- and L-ring assembly, we examined the effect of a null muta
Autor:
Christian D. Mohr, Vojo Deretic
Publikováno v:
Biochemical and Biophysical Research Communications. 189:837-844
The ability of the histone-like element Integration Host Factor (IHF) to interact with the algD promoter was investigated. IHF from Escherichia coli was found to bind to the algD promoter and to form multiple protein-DNA complexes in gel mobility shi
Publikováno v:
Molecular Microbiology. 6:2761-2767
Summary AlgR is a transcriptional regulator of mucoidy in Pseudomonas aeruginosa, a critical virulence factor expressed in cystic fibrosis. AlgR belongs to the superfamily of bacterial signal transduction systems, and has been shown to bind to the al
Publikováno v:
Scopus-Elsevier
Strong transcriptional activation of algD, a key event in the overproduction of alginate and establishment of mucoidy in Pseudomonas aeruginosa, depends on the functional algR gene. The predicted gene product of algR shows homologies to response regu
Publikováno v:
Scopus-Elsevier
Summary The profuse production of the exopolysaccharide alginate results in mucoidy, a critical virulence factor expressed by Pseudomonas aeruginosa during chronic respiratory tract infections in cystic fibrosis. Studies of the regulation of this pat
Autor:
Mladen Tomich, Christian D. Mohr
Publikováno v:
FEMS microbiology letters. 228(2)
Cable pili are unique peritrichous adherence organelles expressed by certain strains of the opportunistic human pathogen Burkholderia cenocepacia. Cable pili have been proposed to facilitate binding to human epithelial cells and mucin, and may play a