Fusel Alcohols Regulate Translation Initiation by Inhibiting eIF2B to Reduce Ternary Complex in a Mechanism That May Involve Altering the Integrity and Dynamics of the eIF2B Body

Autor: Mark P. Ashe, Graham D. Pavitt, Paul F. G. Sims, Susan G. Campbell, Christian D. Griffiths, Peter J. Reid, Eleanor Taylor, Daniela Delneri, Richard J. Harrison, John W. Slaven

Publikováno v: Molecular Biology of the Cell 21 (2010) 13
Molecular Biology of the Cell, 21(13), 2202-2216
Molecular Biology of the Cell

This study highlights a connection between the eIF2B body and the regulation of translation initiation as a response to stress in Saccharomyces cerevisiae. Fusel alcohols are involved in signaling nitrogen scarcity to the cell and they inhibit protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef476c0ed86ad62f0e93d1de8fc13ec9
https://doi.org/10.1091/mbc.e09-11-0962