Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Christian Coulombeau"'
Autor:
Julian Garcia, Anne-Gaëlle Bourdat, Yoann Roupioz, Jean Lhomme, Christian Coulombeau, Eric Defrancq, Mitsuharu Kotera
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
On the basis of molecular modeling studies, the 7-nitroindole nucleoside 1 was selected as a suitable photochemical precursor for photochemical generation of the C1′ deoxyribosyl radical under irradiation, which led to 2′-deoxyribonolactone. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdd3162e21e9e194702678e8af5bce9
https://doi.org/10.1002/1521-3765(20001117)6:22<4163::aid-chem4163>3.0.co
https://doi.org/10.1002/1521-3765(20001117)6:22<4163::aid-chem4163>3.0.co
Autor:
Christian Coulombeau, Leila Ayadi, Damien Forget, Alain Martelli, Jean-François Constant, Martine Demeunynck
Publikováno v:
Theoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta). 104:284-289
We use molecular modeling calculations to study the structure and the flexibility of abasic (AP sites) and for the design of anticancer drugs targeted against AP sites. For either adenine or cytosine on the opposing strand within the same sequence co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::262b370db0cb4e8626fe08add6aa08f0
https://doi.org/10.1007/s002140000140
https://doi.org/10.1007/s002140000140
Publikováno v:
Tetrahedron: Asymmetry. 11:2885-2898
A method has been developed for determining the enantiomeric purity and the absolute configuration of β-aminoalcohols of type ArOCH2CH(OH)CH2NHR (R=iPr, tBu). To determine enantiomeric purity, the amine function was first protected by a benzyl group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::185260719675e88be916b39127755b52
https://doi.org/10.1016/s0957-4166(00)00254-8
https://doi.org/10.1016/s0957-4166(00)00254-8
Publikováno v:
ResearcherID
Molecular modeling calculations using JUnction Minimization of Nucleic Acids (JUMNA) have been used to study sequence effects on the conformation of abasic sites within duplex DNA. We have considered lesions leading to all possible unpaired bases (X)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376f0ac8b9ad7b202920c5a93079276d
Autor:
Ura Cnrs, Mahmoud Ghomi, AVenue A. Einstein, Othman Bouloussa, Nicolas Leulliot, Vladimír Baumruk, Christian Coulombeau
Publikováno v:
The Journal of Physical Chemistry B. 103:10934-10944
Vibrational spectra of two ribonucleosides containing pyrimidine bases, i.e., uridine and cytidine, were analyzed in the solid state at low temperature by neutron inelastic scattering (NIS) and in an aqueous solution at room temperature by Raman scat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec0160ba5f419fb2f91ce419c8e6a918
https://doi.org/10.1021/jp9921147
https://doi.org/10.1021/jp9921147
Autor:
Leila Ayadi, Christian Coulombeau
Publikováno v:
Theoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta). 101:121-125
Molecular mechanics calculations were performed with the JUMNA program on d(GCGTGOGTGCG) · d(CGCACTCACGC) where “O” is a modified abasic site: 3-hydroxy-2-(hydroxymethyl)tetrahydrofuran. From energy minimizations, for intrahelical or extrahelica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32ce7eedd222830e7b1db24b44887f2a
https://doi.org/10.1007/s002140050417
https://doi.org/10.1007/s002140050417
Publikováno v:
Chemistry - A European Journal. 3:969-973
The (aR, aR, aR) and (aS, aS, aS) enantiomers of a chiral macrobicyclic ligand with a bicapped tris(binaphthol) structure were synthesized. Complexation of gallium(III), chromium(III) and iron(III) centres in the chiral cavities of these two ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7677acfd8a8b0fce1d0699fbfcea5d0
https://doi.org/10.1002/chem.19970030619
https://doi.org/10.1002/chem.19970030619
Autor:
Jean-François Constant, Christian Coulombeau, Yannick Coppel, Jean Lhomme, Martine Demeunynck, Julian Garcia
Publikováno v:
Biochemistry. 36:4831-4843
Tailor-made molecules, DTAc and ATAc, that incorporate a nucleic base (adenine or 2,6-diaminopurine) linked by a diamino chain to an intercalator (9-amino-6-chloro-2-methoxyacridine) selectively recognize and efficiently cleave abasic sites in DNA vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d9c05e69ae50d271d6ecae9c426e48
https://doi.org/10.1021/bi962678q
https://doi.org/10.1021/bi962678q
Autor:
J. Lhomme, Nathalie Berthet, Marie Louise Dheu-Andries, Christian Coulombeau, Laurence Fouilloux, Julian Garcia, C. Coulombeau, Pierre Vatton
Publikováno v:
Journal of Molecular Structure: THEOCHEM. 330:417-422
Molecular modeling of a DNA undecamer and a corresponding DNA apurinic undecamer (d(CGCACXCACGC) d(GCGTGTGTGCG), X = A or apurinic site) has been performed using the jumna program. Among the possible structures, several are slightly distorted and cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b596a4c139b48d406ddedf3d479471f
https://doi.org/10.1016/0166-1280(94)03870-q
https://doi.org/10.1016/0166-1280(94)03870-q
Publikováno v:
Fullerene Science and Technology. 2:247-254
New experimental data on the vibrational spectrum of C60 have been recorded with neutron inelastic scattering (NIS). These data modify the positions of the lattice modes, which previously were reported at too high frequencies. New information on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44d6378df38db62615c5752b2bb5f10c
https://doi.org/10.1080/15363839408009550
https://doi.org/10.1080/15363839408009550