Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Christian Cayer"'
Autor:
Anthony Murkar, Christian Cayer, Jon James, Tony Durst, John T. Arnason, Pablos E. Sanchez-Vindas, M. Otarola Rojas, Zul Merali
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Background:Souroubea sympetala Gilg. is a neotropical vine native to Central America, investigated as part of a targeted study of the plant family Marcgraviaceae. Our previous research showed that extract of S. sympetala leaf and small branch extract
Externí odkaz:
https://doaj.org/article/4791dfb1271442f7b939a214bd7a0194
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Background: Δ9-Tetrahydrocannabinol (THC, a CB1 receptor agonist) and Cannabidiol (CBD, a non-competitive antagonist of endogenous CB1 and CB2 ligands) are two primary components of Cannabis species, and may modulate fear learning in mammals. The CB
Externí odkaz:
https://doaj.org/article/f41ae264fdb045b5868995bfacdea3b4
Autor:
Eliza Fatima Ali, Jennifer Christine MacKay, Samantha Graitson, Jonathan Stewart James, Christian Cayer, Marie-Claude Audet, Pamela Kent, Alfonso Abizaid, Zul Merali
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
The juvenile period is marked by a reorganization and growth of important brain regions including structures associating with reward seeking behaviors such as the nucleus accumbens (NA) and prefrontal cortex (PFC). These changes are impacted by stres
Externí odkaz:
https://doaj.org/article/6382b28ba02d4e8c9443f0fc18962c5f
Autor:
Jennifer Christine MacKay, Jonathan Stewart James, Christian Cayer, Pamela Kent, Hymie Anisman, Zul Merali
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96573 (2014)
Stressor experiences during the juvenile period may increase vulnerability to anxiety and depressive-like symptoms in adulthood. Stressors may also promote palatable feeding, possibly reflecting a form of self-medication. The current study investigat
Externí odkaz:
https://doaj.org/article/324ecd0466fc4905997273a5fe6b041e
Publikováno v:
Behavioural Brain Research. 347:255-262
Background Gastrin Releasing Peptide (GRP) may play a role in fear learning. The GRP Receptor is expressed in the basolateral amygdala and hippocampus, and central administration of GRP mediates fear learning. The effects of GRP on reconsolidation, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd204fc18214e28edaf0771b7af5c43
https://doi.org/10.1016/j.bbr.2017.11.037
https://doi.org/10.1016/j.bbr.2017.11.037
Autor:
Cory S. Harris, Zul Merali, Christian Cayer, Rui Liu, Pamela Kent, Victor Cal, John T. Arnason
Publikováno v:
Journal of Ethnopharmacology. 216:63-70
Ethnopharmacological relevance The Maya have traditionally used copal, Protium copal, as incense during ceremonies since pre-Columbian times. Anecdotally, copal (when burned as incense), is thought to elicit mentally uplifting and calming effects. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf6a8d8e7482e6f2463489e346b4405
https://doi.org/10.1016/j.jep.2018.01.027
https://doi.org/10.1016/j.jep.2018.01.027
Publikováno v:
Physiology & Behavior. 177:113-121
In adult rats, access to a palatable diet can buffer against the effects of stressors. Approximately 10% of all adolescents are repeatedly victimized by their peers raising the possibility that palatable food consumption may be relevant to this devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740fcee08f73ed6e1795a29b9409a4c2
https://doi.org/10.1016/j.physbeh.2017.04.002
https://doi.org/10.1016/j.physbeh.2017.04.002
Autor:
Zulfiquar Merali, John T. Arnason, Alain Cuerrier, Christian Cayer, Jon James, Pamela Kent, Anthony Murkar
Publikováno v:
Planta Medica International Open. 3:e77-e80
Rhodiola rosea is a plant with adaptogenic qualities used by Inuit populations of Nunavik, Quebec (Canada) for general mental and physical rejuvenation. Previous studies have demonstrated that the Canadian populations of R. rosea significantly attenu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::876a5a4800467267b72d159e6565449a
https://doi.org/10.1055/s-0042-112461
https://doi.org/10.1055/s-0042-112461
Autor:
Alisha Awadia, Pamela Kent, Hymie Anisman, Jonathan S. James, Zul Merali, Donna Ensan, Dinuka Silva, Leah Zhao, Christian Cayer
Publikováno v:
Psychoneuroendocrinology. 64:123-130
The intranasal route of drug administration has gained increased popularity as it is thought to allow large molecules, such as peptide hormones, more direct access to the brain, while limiting systemic exposure. Several studies have investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1579dc9ad8d7c27a6c6b989386d86d6c
https://doi.org/10.1016/j.psyneuen.2015.11.019
https://doi.org/10.1016/j.psyneuen.2015.11.019
Autor:
P. Sánchez, Martha Mullally, Tony Durst, Rui Liu, Christian Cayer, Luis Poveda, Zul Merali, Marco Otarola Rojas, Mario Garcia, Aleksandar Masic, Ana Francis Carballo, John T. Arnason, John Baker, Fida Ahmed
Publikováno v:
The AAPS journal. 19(6)
As part of our ongoing research into botanical therapies for anxiety disorders, the neotropical vine Souroubea sympetala was chosen for study as a phytochemical discovery strategy focusing on rare Central American plant families. When orally administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c3781a7debc2583535969a0eca580f
https://pubmed.ncbi.nlm.nih.gov/28895076
https://pubmed.ncbi.nlm.nih.gov/28895076