Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Christian C, Dibble"'
Autor:
Christian C. Dibble, Samuel A. Barritt, Grace E. Perry, Evan C. Lien, Renee C. Geck, Sarah E. DuBois-Coyne, David Bartee, Thomas T. Zengeya, Emily B. Cohen, Min Yuan, Benjamin D. Hopkins, Jordan L. Meier, John G. Clohessy, John M. Asara, Lewis C. Cantley, Alex Toker
Publikováno v:
Nature. 608:192-198
In response to hormones and growth factors, the class I phosphoinositide-3-kinase (PI3K) signalling network functions as a major regulator of metabolism and growth, governing cellular nutrient uptake, energy generation, reducing cofactor production a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a671b67118b568aca77aca5b34c77ee1
https://doi.org/10.1038/s41586-022-04984-8
https://doi.org/10.1038/s41586-022-04984-8
Autor:
Yun Pyo Kang, Laura Torrente, Aimee Falzone, Cody M Elkins, Min Liu, John M Asara, Christian C Dibble, Gina DeNicola
Publikováno v:
eLife, Vol 8 (2019)
Externí odkaz:
https://doaj.org/article/647f04801f994c3f9dfc7b94e8ac133f
Autor:
Yun Pyo Kang, Laura Torrente, Aimee Falzone, Cody M Elkins, Min Liu, John M Asara, Christian C Dibble, Gina M DeNicola
Publikováno v:
eLife, Vol 8 (2019)
NRF2 is emerging as a major regulator of cellular metabolism. However, most studies have been performed in cancer cells, where co-occurring mutations and tumor selective pressures complicate the influence of NRF2 on metabolism. Here we use geneticall
Externí odkaz:
https://doaj.org/article/584844c4953b4e4591b5737d06acb0d4
Autor:
Paul S. Mischel, Albert S. Baldwin, Brendan D. Manning, Timothy F. Cloughesy, Webster K. Cavenee, Joseph F. Gera, Harry V. Vinters, William H. Yong, Amanda Rinkenbaugh, Hancai Dan, Christian C. Dibble, Yinan Zhang, Ali Nael Amzajerdi, Jason De Jesus, Huijun Yang, Shaojun Zhu, Julie Dang, Beatrice Gini, Deliang Guo, David Akhavan, David Nathanson, Ivan Babic, Kazuhiro Tanaka
mp3 file (9.8 MB). In the November edition of the Cancer Discovery podcast, Executive Editor Mark Landis talks with Paul S. Mischel about his paper, which identifies mTORC2 as a novel mediator of drug resistance and regulator of NF-κB signaling in g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4336e4051cb4e2b78ec5da7f25450ff2
https://doi.org/10.1158/2159-8290.22528563.v1
https://doi.org/10.1158/2159-8290.22528563.v1
Autor:
Paul S. Mischel, Albert S. Baldwin, Brendan D. Manning, Timothy F. Cloughesy, Webster K. Cavenee, Joseph F. Gera, Harry V. Vinters, William H. Yong, Amanda Rinkenbaugh, Hancai Dan, Christian C. Dibble, Yinan Zhang, Ali Nael Amzajerdi, Jason De Jesus, Huijun Yang, Shaojun Zhu, Julie Dang, Beatrice Gini, Deliang Guo, David Akhavan, David Nathanson, Ivan Babic, Kazuhiro Tanaka
PDF file - 1MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525273fc08b1c0321f58bf1ee50af8fb
https://doi.org/10.1158/2159-8290.22528560
https://doi.org/10.1158/2159-8290.22528560
Autor:
Paul S. Mischel, Albert S. Baldwin, Brendan D. Manning, Timothy F. Cloughesy, Webster K. Cavenee, Joseph F. Gera, Harry V. Vinters, William H. Yong, Amanda Rinkenbaugh, Hancai Dan, Christian C. Dibble, Yinan Zhang, Ali Nael Amzajerdi, Jason De Jesus, Huijun Yang, Shaojun Zhu, Julie Dang, Beatrice Gini, Deliang Guo, David Akhavan, David Nathanson, Ivan Babic, Kazuhiro Tanaka
PDF file - 161K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559f43a7ecf9af292e3a1e6ef36f6259
https://doi.org/10.1158/2159-8290.22528557.v1
https://doi.org/10.1158/2159-8290.22528557.v1
Autor:
Patrick Jouandin, Zvonimir Marelja, Yung-Hsin Shih, Andrey A. Parkhitko, Miriam Dambowsky, John M. Asara, Ivan Nemazanyy, Christian C. Dibble, Matias Simons, Norbert Perrimon
Publikováno v:
Science
Adaptation to nutrient scarcity involves an orchestrated response of metabolic and signaling pathways to maintain homeostasis. We find that in the fat body of fasting Drosophila , lysosomal export of cystine coordinates remobilization of internal nut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bedc6855043cebdbbde34944a47c10f
https://doi.org/10.1126/science.abc4203
https://doi.org/10.1126/science.abc4203
Autor:
Christian C, Dibble, Samuel A, Barritt, Grace E, Perry, Evan C, Lien, Renee C, Geck, Sarah E, DuBois-Coyne, David, Bartee, Thomas T, Zengeya, Emily B, Cohen, Min, Yuan, Benjamin D, Hopkins, Jordan L, Meier, John G, Clohessy, John M, Asara, Lewis C, Cantley, Alex, Toker
Publikováno v:
Nature. 608(7921)
In response to hormones and growth factors, the class I phosphoinositide-3-kinase (PI3K) signalling network functions as a major regulator of metabolism and growth, governing cellular nutrient uptake, energy generation, reducing cofactor production a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b4b85ea68d475a44f61a5c11a3fe492
https://pubmed.ncbi.nlm.nih.gov/35896750
https://pubmed.ncbi.nlm.nih.gov/35896750
Publikováno v:
Current Opinion in Cell Biology. 45:62-71
The phosphoinositide 3-kinase (PI3K) signaling pathway is one of the most frequently altered pathways in human cancer and has a critical role in driving tumor initiation and progression. Although PI3K and its lipid product phosphatidylinositol-3,4,5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ef5be191f226a0d3264694f27473ff
https://doi.org/10.1016/j.ceb.2017.02.007
https://doi.org/10.1016/j.ceb.2017.02.007
Autor:
Laura Torrente, Gina M. DeNicola, John M. Asara, Yun Pyo Kang, Aimee Falzone, Min Liu, Cody M Elkins, Christian C. Dibble
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
NRF2 is emerging as a major regulator of cellular metabolism. However, most studies have been performed in cancer cells, where co-occurring mutations and tumor selective pressures complicate the influence of NRF2 on metabolism. Here we use geneticall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d468bd906b4298aff883827cf26f8478
https://elifesciences.org/articles/52671
https://elifesciences.org/articles/52671