Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Christian Bortolini"'
Autor:
Georgina Benn, Maxim G. Ryadnov, Irina V. Mikheyeva, Bart W. Hoogenboom, Joel C. Forster, Thomas J. Silhavy, Nikola Ojkic, Patrick George Inns, Colin Kleanthous, Christian Bortolini
Publikováno v:
Proceedings of the National Academy of Sciences. 118
Gram-negative bacteria are surrounded by a protective outer membrane (OM) with phospholipids in its inner leaflet and lipopolysaccharides (LPS) in its outer leaflet. The OM is also populated with many β-barrel outer-membrane proteins (OMPs), some of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007a134c6ff9c6bf045d971a2b43502e
https://doi.org/10.1073/pnas.2112237118
https://doi.org/10.1073/pnas.2112237118
Autor:
Georgina, Benn, Irina V, Mikheyeva, Patrick George, Inns, Joel C, Forster, Nikola, Ojkic, Christian, Bortolini, Maxim G, Ryadnov, Colin, Kleanthous, Thomas J, Silhavy, Bart W, Hoogenboom
Publikováno v:
Proc Natl Acad Sci U S A
Gram-negative bacteria are surrounded by a protective outer membrane (OM) with phospholipids in its inner leaflet and lipopolysaccharides (LPS) in its outer leaflet. The OM is also populated with many β-barrel outer-membrane proteins (OMPs), some of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9b904dd87babb213d5d99785adcd580
https://pubmed.ncbi.nlm.nih.gov/34716276
https://pubmed.ncbi.nlm.nih.gov/34716276
Direct on-surface synthesis of gold–phthalocyanine via cyclization of cyano-groups with gold adatoms
Autor:
Menglin Chen, Sheng Wei, Li Wang, Zhongping Wang, Xiaoqing Liu, Junfa Zhu, Christian Bortolini, Yan Lu, Huanxin Ju, Wei Li, Federico Rosei, Mingdong Dong, Zegao Wang
Publikováno v:
Wang, Z, Liu, X, Lu, Y, Wang, Z, Bortolini, C, Chen, M, Wei, S, Li, W, Zhu, J, Ju, H, Rosei, F, Dong, M & Wang, L 2019, ' Direct on-surface synthesis of gold-phthalocyanine : Via cyclization of cyano-groups with gold adatoms ', Materials Chemistry Frontiers, vol. 3, no. 7, pp. 1406-1410 . https://doi.org/10.1039/c9qm00070d
We report the synthesis of gold-phthalocyanines on an Au(111) surface via cyclization of dibenzo[fg,op]tetracene-5,6,12,13-tetracarbonitrile molecules. Scanning tunnelling microscopic images unambiguously reveal that gold adatoms act as linkers via m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e90b6e7ffe4bf50ee7cc13e9f8126065
https://doi.org/10.1039/c9qm00070d
https://doi.org/10.1039/c9qm00070d
Autor:
Christian Bortolini, Itzel Condado Morales, Tadas Kartanas, Pavan K. Challa, Mingdong Dong, Giuliano Siligardi, Tuomas P. J. Knowles, Jerome Charmet, Tamás Jávorfi, Yuewen Zhang, Davor Copic, Rohanah Hussain, Quentin Peter
Publikováno v:
Lab on a Chip
Bortolini, C, Kartanas, T, Copic, D, Condado Morales, I, Zhang, Y, Challa, P K, Peter, Q, Jávorfi, T, Hussain, R, Dong, M, Siligardi, G, Knowles, T P J & Charmet, J 2019, ' Resolving protein mixtures using microfluidic diffusional sizing combined with synchrotron radiation circular dichroism ', Lab on a Chip, vol. 19, no. 1, pp. 50-58 . https://doi.org/10.1039/c8lc00757h
Bortolini, C, Kartanas, T, Copic, D, Condado Morales, I, Zhang, Y, Challa, P K, Peter, Q, Jávorfi, T, Hussain, R, Dong, M, Siligardi, G, Knowles, T P J & Charmet, J 2019, ' Resolving protein mixtures using microfluidic diffusional sizing combined with synchrotron radiation circular dichroism ', Lab on a Chip, vol. 19, no. 1, pp. 50-58 . https://doi.org/10.1039/c8lc00757h
Circular dichroism spectroscopy has become a powerful tool to characterise proteins and other biomolecules. For heterogeneous samples such as those present for interacting proteins, typically only average spectroscopic features can be resolved. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0b0e8402f11de620672cfbf0692a0f
https://doi.org/10.1039/c8lc00757h
https://doi.org/10.1039/c8lc00757h
Autor:
Lin, Lin, Haiying, Cui, Guanghong, Zeng, Menglin, Chen, Haifang, Zhang, Mingqiang, Xu, Xiangqian, Shen, Christian, Bortolini, Mingdong, Dong
Publikováno v:
Journal of materials chemistry. B. 1(21)
Copper ferrite (CuFe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67f445c27c7b75e85c66b35cb9d1e565
https://pubmed.ncbi.nlm.nih.gov/32260977
https://pubmed.ncbi.nlm.nih.gov/32260977
Publikováno v:
Zhang, H X, Liu, L, Wang, J, Bortolini, C & Dong, M 2018, ' Thermal effect on the degradation of hIAPP 20–29 fibrils ', Journal of Colloid and Interface Science, vol. 513, pp. 126-132 . https://doi.org/10.1016/j.jcis.2017.10.107
Uncontrolled misfolding of proteins resulting in the formation of amyloid deposits is associated with over 40 types of diseases, for instance, type-2 diabetes. The human Islet amyloid polypeptide (hIAPP) amyloid formation is thought to be the cause o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd5f0b4743373a207205da1564b550b
https://doi.org/10.1016/j.jcis.2017.10.107
https://doi.org/10.1016/j.jcis.2017.10.107
Autor:
Mingdong Dong, Christian Bortolini, Søren Vrønning Hoffmann, Nykola C. Jones, Tuomas P. J. Knowles, Lei Liu
Publikováno v:
Bortolini, C, Liu, L, Hoffmann, S V, Jones, N C, Knowles, T P J & Dong, M 2017, ' Exciton Coupling of Phenylalanine Reveals Conformational Changes of Cationic Peptides ', Chemistry Select, vol. 2, no. 8, pp. 2476-2479 . https://doi.org/10.1002/slct.201601916
Circular dichroism (CD) is a versatile tool to investigate the secondary structure of proteins. Conventionally, CD signals in the far-UV region are primarily attributed to peptide bond absorption; likewise aromatic residue analysis has typically only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bed4b78f03a7ca0b126d6c6c0591223
https://doi.org/10.1002/slct.201601916
https://doi.org/10.1002/slct.201601916
Autor:
Mingdong Dong, Daniela Saadeh, Nykola C. Jones, Tuomas P. J. Knowles, Lasse Hyldgaard Klausen, Zegao Wang, Christian Bortolini, Søren Vrønning Hoffmann
Publikováno v:
Bortolini, C, Klausen, L H, Hoffmann, S V, Jones, N C, Saadeh, D, Wang, Z, Knowles, T P J & Dong, MD 2018, ' Rapid Growth of Acetylated Aβ(16–20) into Macroscopic Crystals ', ACS Nano, vol. 12, no. 6, pp. 5408-5416 . https://doi.org/10.1021/acsnano.8b00448
Aberrant assembly of the amyloid-β (Aβ) is responsible for the development of Alzheimer’s disease, but can also be exploited to obtain highly functional biomaterials. The short Aβ fragment, KLVFF (Aβ16–20), is crucial for Aβ assembly and con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd68e53db211f23a77c520d169d6adb
https://pubmed.ncbi.nlm.nih.gov/29771495
https://pubmed.ncbi.nlm.nih.gov/29771495
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Song, Y, Li, P, Liu, L, Bortolini, C & Dong, M 2018, ' Nanostructural Differentiation and Toxicity of Amyloid-β25-35 Aggregates Ensue from Distinct Secondary Conformation ', Scientific Reports, vol. 8, 765 . https://doi.org/10.1038/s41598-017-19106-y
Scientific Reports
Song, Y, Li, P, Liu, L, Bortolini, C & Dong, M 2018, ' Nanostructural Differentiation and Toxicity of Amyloid-β25-35 Aggregates Ensue from Distinct Secondary Conformation ', Scientific Reports, vol. 8, 765 . https://doi.org/10.1038/s41598-017-19106-y
Amyloid nanostructures are originated from protein misfolding and aberrant aggregation, which is associated with the pathogenesis of many types of degenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and Huntington’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b7b7da43e019c7b983eb633241dac0
https://doi.org/10.1038/s41598-017-19106-y
https://doi.org/10.1038/s41598-017-19106-y
Publikováno v:
Journal of colloid and interface science. 513
Uncontrolled misfolding of proteins resulting in the formation of amyloid deposits is associated with over 40 types of diseases, for instance, type-2 diabetes. The human Islet amyloid polypeptide (hIAPP) amyloid formation is thought to be the cause o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a65937235e61dffdfd100955a06672c0
https://pubmed.ncbi.nlm.nih.gov/29145016
https://pubmed.ncbi.nlm.nih.gov/29145016