Výsledky vyhledávání - "Christian Bleau"

Akademický článek

Pathogenic mouse hepatitis virus or poly(I:C) induce IL-33 in hepatocytes in murine models of hepatitis.

Autor: Muhammad Imran Arshad, Solène Patrat-Delon, Claire Piquet-Pellorce, Annie L'helgoualc'h, Michel Rauch, Valentine Genet, Catherine Lucas-Clerc, Christian Bleau, Lucie Lamontagne, Michel Samson

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e74278 (2013)

The IL-33/ST2 axis is known to be involved in liver pathologies. Although, the IL-33 levels increased in sera of viral hepatitis patients in human, the cellular sources of IL-33 in viral hepatitis remained obscure. Therefore, we aimed to investigate

Externí odkaz: https://doaj.org/article/f7513822065e4ae18d280bf5d51e864a

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Crosstalk between intestinal microbiota, adipose tissue and skeletal muscle as an early event in systemic low-grade inflammation and the development of obesity and diabetes

Autor: Christian Bleau, Lucie Lamontagne, David H. St-Pierre, Antony D. Karelis

Publikováno v: Diabetes/Metabolism Research and Reviews. 31:545-561

Obesity is associated with a systemic chronic low-grade inflammation that contributes to the development of metabolic disorders such as cardiovascular diseases and type 2 diabetes. However, the etiology of this obesity-related pro-inflammatory proces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bdfd947ad1572fc7a604f1d68537924
https://doi.org/10.1002/dmrr.2617

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Dual infections with low virulent chicken infectious anaemia virus (lvCIAV) and intermediate infectious bursal disease virus (iIBDV) in young chicks increase lvCIAV in thymus and bursa while decreasing lymphocyte disorders induced by iIBDV

Autor: Christian Bleau, Amer Silim, Diane Frenette, Lucie Lamontagne, Asaad Vaziry

Publikováno v: Avian Pathology. 42:88-99

The use of attenuated vaccines or the occurrence of low virulent T-lymphotropic or B-lymphotropic viruses in flocks may alter the immune responses of young chicks in spite of the absence of clinical signs. Infections with a low virulent T-lymphotropi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db8bec20e38a18b4f7de1c499b5426b
https://doi.org/10.1080/03079457.2013.766306

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Mouse Hepatitis Virus Infection Induces a Toll-Like Receptor 2-Dependent Activation of Inflammatory Functions in Liver Sinusoidal Endothelial Cells during Acute Hepatitis

Autor: Michel Samson, Lucie Lamontagne, Christian Bleau, Aveline Filliol

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2016, 90 (20), pp.9096--9113. ⟨10.1128/JVI.01069-16⟩
Journal of Virology, 2016, 90 (20), pp.9096--9113. ⟨10.1128/JVI.01069-16⟩

Under physiological conditions, the liver sinusoidal endothelial cells (LSECs) mediate hepatic immune tolerance toward self or foreign antigens through constitutive expression of anti-inflammatory mediators. However, upon viral infection or Toll-like

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89436c5837efb6500ee4f683696f88f5
https://europepmc.org/articles/PMC5044860/

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Toll-like receptor-2 exacerbates murine acute viral hepatitis

Autor: Aveline Filliol, Lucie Lamontagne, Christian Bleau, Claire Piquet-Pellorce, Mélanie Burnette, Michel Samson

Publikováno v: Immunology
Immunology, Wiley, 2016, 149 (2), pp.204--224. ⟨10.1111/imm.12627⟩
Immunology, 2016, 149 (2), pp.204--224. ⟨10.1111/imm.12627⟩

International audience; Viral replication in the liver is generally detected by cellular endosomal Toll-like receptors (TLRs) and cytosolic helicase sensors that trigger antiviral inflammatory responses. Recent evidence suggests that surface TLR2 may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5974de4534a2de24eb559b857ab341
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01373946/document

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Macrophage interleukin-6 and tumour necrosis factor-α are induced by coronavirus fixation to Toll-like receptor 2/heparan sulphate receptors but not carcinoembryonic cell adhesion antigen 1a

Autor: Lucie Lamontagne, Christian Bleau, Claire Turbide, Alexandre Jacques, Nicole Beauchemin

Publikováno v: Immunology

A rapid antiviral immune response may be related to viral interaction with the host cell leading to activation of macrophages via pattern recognition receptors (PPRs) or specific viral receptors. Carcinoembryonic cell adhesion antigen 1a (CEACAM1a) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602606ba8816622b5099e7f9cc755fbc

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Intrahepatic endothelial and Kupffer cells involved in immunosuppressive cytokines and natural killer (NK)/NK T cell disorders in viral acute hepatitis

Autor: Alexandre Jacques, Christian Bleau, J.-P. Martin, Lucie Lamontagne

Publikováno v: Clinical & Experimental Immunology

SummaryDuring acute viral hepatitis, the intrahepatic tolerance sustained by immunosuppressive cytokines such as interleukin (IL)-4, IL-10, transforming growth factor (TGF)-β and prostaglandin E2 (PGE2), produced by Kupffer cells (KC), liver sinusoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c4370aaec3e3d90fda05bcc7488a4a

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Efficacité de la poly-glucosamine Oligo-Flex MD contre l’inflammation articulaire

Autor: Pauline Cayer, Nathalie Côté, Isabelle Boucher, Christian Bleau, Lucie Lamontagne, Alexia Monges

Publikováno v: Phytothérapie. 5:27-31

Le chitosane est une molecule retrouvee naturellement dans les carapaces de crustaces marins. Les derives obtenus par hydrolyse de cette molecule possedent plusieurs proprietes biologiques interessantes au niveau nutraceutique. Des experiences dans u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95a3c342ac71e5c7566e20912f8bdd83
https://doi.org/10.1007/s10298-007-0231-9

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Brain Invasion by Mouse Hepatitis Virus Depends on Impairment of Tight Junctions and Beta Interferon Production in Brain Microvascular Endothelial Cells

Autor: Aveline Filliol, Christian Bleau, Michel Samson, Lucie Lamontagne

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2015, 89 (19), pp.9896-9908. ⟨10.1128/JVI.01501-15⟩
Journal of Virology, 2015, 89 (19), pp.9896-9908. ⟨10.1128/JVI.01501-15⟩

Coronaviruses (CoVs) have shown neuroinvasive properties in humans and animals secondary to replication in peripheral organs, but the mechanism of neuroinvasion is unknown. The major aim of our work was to evaluate the ability of CoVs to enter the ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc25f40ad95f28dad1c012a77c83b769
https://pubmed.ncbi.nlm.nih.gov/26202229

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New Lactobacillus acidophilus isolates reduce the release of leptin by murine adipocytes leading to lower interferon-γ production

Autor: Christian Bleau, Lucie Lamontagne, Roland Savard

Publikováno v: Clinical and Experimental Immunology. 140:427-435

Summary Leptin produced by adipocytes increases Th1-dependent immunostimulation and autoimmune diseases. Lactobacilli are known to promote or suppress Th1 responses according to the isolates. We have investigated whether the sensitivity of Suriss Jim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d5f482aee3d19d603fdf8f72cff914
https://doi.org/10.1111/j.1365-2249.2005.02785.x

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