Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christian B. Vægter"'
Autor:
Alberto Delaidelli, Mette Richner, Lixiang Jiang, Amelia van der Laan, Ida Bergholdt Jul Christiansen, Nelson Ferreira, Jens R. Nyengaard, Christian B. Vægter, Poul H. Jensen, Ian R. Mackenzie, Poul H. Sorensen, Asad Jan
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract Circumstantial evidence points to a pathological role of alpha-synuclein (aSyn; gene symbol SNCA), conferred by aSyn misfolding and aggregation, in Parkinson disease (PD) and related synucleinopathies. Several findings in experimental models
Externí odkaz:
https://doaj.org/article/4556178dc7c94ccab3861fb11cbb6d65
Autor:
Giulia Monti, Mads Kjolby, Anne Mette G. Jensen, Mariet Allen, Juliane Reiche, Peter L. Møller, Raquel Comaposada-Baró, Bartlomiej E. Zolkowski, Cármen Vieira, Margarita Melnikova Jørgensen, Ida E. Holm, Paul N. Valdmanis, Niels Wellner, Christian B. Vægter, Sarah J. Lincoln, Anders Nykjær, Nilüfer Ertekin-Taner, Jessica E. Young, Mette Nyegaard, Olav M. Andersen
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract SORL1 is strongly associated with both sporadic and familial forms of Alzheimer’s disease (AD), but a lack of information about alternatively spliced transcripts currently limits our understanding of the role of SORL1 in AD. Here, we descr
Externí odkaz:
https://doaj.org/article/6593f8c6612a4dd48b7424bbb99fda5f
Autor:
Maj Ulrichsen, Nádia P. Gonçalves, Simin Mohseni, Simone Hjæresen, Thomas L. Lisle, Simon Molgaard, Niels K. Madsen, Olav M. Andersen, Åsa F. Svenningsen, Simon Glerup, Anders Nykjær, Christian B. Vægter
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Peripheral nerve regeneration relies on the ability of Schwann cells to support the regrowth of damaged axons. Schwann cells re-differentiate when reestablishing contact with the sprouting axons, with large fibers becoming remyelinated and small noci
Externí odkaz:
https://doaj.org/article/bcae94cc172b4370bc61ba92c676e879
Autor:
Nádia P. Gonçalves, Simin Mohseni, Marwa El Soury, Maj Ulrichsen, Mette Richner, Junhua Xiao, Rhiannon J. Wood, Olav M. Andersen, Elizabeth J. Coulson, Stefania Raimondo, Simon S. Murray, Christian B. Vægter
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Schwann cell reprogramming and differentiation are crucial prerequisites for neuronal regeneration and re-myelination to occur following injury to peripheral nerves. The neurotrophin receptor p75NTR has been identified as a positive modulator for Sch
Externí odkaz:
https://doaj.org/article/e730f8d20bf64674989c26d7b2e763df
Autor:
Mette Richner, Nelson Ferreira, Anete Dudele, Troels S. Jensen, Christian B. Vaegter, Nádia P. Gonçalves
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2019)
The incidence of diabetes mellitus is approaching global epidemic proportions and should be considered a major health-care problem of modern societies in the twenty-first century. Diabetic neuropathy is a common chronic complication of diabetes and,
Externí odkaz:
https://doaj.org/article/81221437adc34194804869008e42dcdf
Autor:
Nádia P. Gonçalves, Yan Yan, Maj Ulrichsen, Morten T. Venø, Ebbe T. Poulsen, Jan J. Enghild, Jørgen Kjems, Christian B. Vægter
Publikováno v:
Biomedicines, Vol 8, Iss 11, p 450 (2020)
Schwann cells (SCs) are the main glial cells of the peripheral nervous system (PNS) and are known to be involved in various pathophysiological processes, such as diabetic neuropathy and nerve regeneration, through neurotrophin signaling. Such glial t
Externí odkaz:
https://doaj.org/article/374c9e98cdad42158472ef9b97e4385a
Autor:
Simon Glerup, Maria Lume, Ditte Olsen, Jens R. Nyengaard, Christian B. Vaegter, Camilla Gustafsen, Erik I. Christensen, Mads Kjolby, Anders Hay-Schmidt, Dirk Bender, Peder Madsen, Mart Saarma, Anders Nykjaer, Claus M. Petersen
Publikováno v:
Cell Reports, Vol 3, Iss 1, Pp 186-199 (2013)
Glial cell-line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor that has reached clinical trials for Parkinson’s disease. GDNF binds to its coreceptor GFRα1 and signals through the transmembrane receptor tyrosine kinase RET, or
Externí odkaz:
https://doaj.org/article/57be80328bf040d6b8ff9eb14d9de451
Autor:
Anne Mette G. Jensen, Yu Kitago, Elnaz Fazeli, Christian B. Vægter, Scott A. Small, Gregory A. Petsko, Olav M. Andersen
Publikováno v:
Jensen, A M G, Kitago, Y, Fazeli, E, Vægter, C B, Small, S A, Petsko, G A & Andersen, O M 2023, ' Dimerization of the Alzheimer's disease pathogenic receptor SORLA regulates its association with retromer ', Proceedings of the National Academy of Sciences, vol. 120, no. 4, e2212180120 . https://doi.org/10.1073/pnas.2212180120
SORL1 , the gene encoding the large multidomain SORLA protein, has emerged as only the fourth gene that when mutated can by itself cause Alzheimer’s disease (AD), and as a gene reliably linked to both the early- and late-onset forms of the disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789be2709cc6de06e9087452c46e1ba1
https://pure.au.dk/portal/da/publications/dimerization-of-the-alzheimers-disease-pathogenic-receptor-sorla-regulates-its-association-with-retromer(4cd16520-6b3c-4451-acc7-b0fd6b8859e4).html
https://pure.au.dk/portal/da/publications/dimerization-of-the-alzheimers-disease-pathogenic-receptor-sorla-regulates-its-association-with-retromer(4cd16520-6b3c-4451-acc7-b0fd6b8859e4).html
Autor:
Nelson Ferreira, Mette Richner, Amelia van der Laan, Ida Bergholdt Jul Christiansen, Christian B. Vægter, Jens R. Nyengaard, Glenda M. Halliday, Joachim Weis, Benoit I. Giasson, Ian R. Mackenzie, Poul H. Jensen, Asad Jan
Publikováno v:
Ferreira, N, Richner, M, van der Laan, A, Jul Christiansen, I B, Vægter, C B, Nyengaard, J R, Halliday, G M, Weis, J, Giasson, B I, Mackenzie, I R, Jensen, P H & Jan, A 2022, ' Correction to : Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy ', Brain Communications, vol. 4, no. 2, pp. fcac067 . https://doi.org/10.1093/braincomms/fcac067
[This corrects the article DOI: 10.1093/braincomms/fcab104.].
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ac372888080a7fbcd975411fed03d6
https://pure.au.dk/portal/da/publications/correction-to(2e2fa0a7-e8dd-4556-b070-ad72e8480c45).html
https://pure.au.dk/portal/da/publications/correction-to(2e2fa0a7-e8dd-4556-b070-ad72e8480c45).html
Autor:
Christian B Vaegter, Pernille Jansen, Anja W Fjorback, Simon Glerup, Sune Skeldal, Mads Kjolby, Mette Richner, Bettina Erdmann, Jens R Nyengaard, Lino Tessarollo, Gary R Lewin, Thomas E Willnow, Moses V Chao, Anders Nykjaer
Publikováno v:
Nature Neuroscience. 14:1217-1217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8187ea639c51b71a5fa45aea77ca7f5e
https://doi.org/10.1038/nn0911-1217a
https://doi.org/10.1038/nn0911-1217a