Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christian Antila"'
Autor:
Christian Antila, Linda K Bergström, Diana M. Toivola, Julia O. Misiorek, Sebastian K.-J. Landor, Cecilia Sahlgren, Carl-Gustaf A Stenvall, Iris A. K. Lähdeniemi, Lina E. Fortelius
Publikováno v:
Cell Death and Differentiation
Keratins (K) are intermediate filament proteins important in stress protection and mechanical support of epithelial tissues. K8, K18 and K19 are the main colonic keratins, and K8-knockout (K8−/−) mice display a keratin dose-dependent hyperprolife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767c0a6515547147b470dcffbbb4ac9f
https://doi.org/10.1038/cdd.2017.28
https://doi.org/10.1038/cdd.2017.28
Autor:
Sebastian K.-J. Landor, Adolfo Rivero-Müller, Fang Cheng, John E. Eriksson, Carlijn V. C. Bouten, Kayla J. Bayless, Kimmo O. Isoniemi, Camille L. Duran, Daniel Antfolk, Rasmus Niemi, Cecilia Sahlgren, Christian Antila, Marika Sjöqvist
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America (PNAS), 114(23). National Academy of Sciences
Notch signaling is a key regulator of angiogenesis, in which sprouting is regulated by an equilibrium between inhibitory Dll4-Notch signaling and promoting Jagged-Notch signaling. Whereas Fringe proteins modify Notch receptors and strengthen their ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5672a74f4d7d32ec76ba3b5c3eb9a58a
https://doi.org/10.1073/pnas.1703057114
https://doi.org/10.1073/pnas.1703057114
Autor:
Lea Sistonen, Christian Antila, Tiina A. Salminen, Vilma Rraklli, Cecilia Sahlgren, Henri A. Blomster, Käthe M. Dahlström, Johan Holmberg
Publikováno v:
Cell Death and Differentiation, 25(3), 600-615. Nature Publishing Group
The Notch signaling pathway is a key regulator of stem cells during development, and its deregulated activity is linked to developmental defects and cancer. Transcriptional activation of Notch target genes requires cleavage of the Notch receptor in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a77724645cf6c2a78b03be1bd96682
https://pubmed.ncbi.nlm.nih.gov/29305585
https://pubmed.ncbi.nlm.nih.gov/29305585
Autor:
Susumu Y. Imanishi, Cecilia Haga, Daniel Antfolk, Cecilia Sahlgren, Christian Antila, Johan Holmberg, Urban Lendahl, Anders P. Mutvei, Vilma Rraklli, Saima E. Ferraris, John E. Eriksson, Marika Sjöqvist, Shao Bo Jin
Publikováno v:
Cell, 24(4), 433-50. Cell Press
Activation of Notch signaling requires intracellular routing of the receptor, but the mechanisms controlling the distinct steps in the routing process is poorly understood. We identify PKCζ as a key regulator of Notch receptor intracellular routing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c2b41b7b0503635702707a20f4ee90
https://research.tue.nl/nl/publications/b18fc813-ae88-467d-aebe-badd7c460c73
https://research.tue.nl/nl/publications/b18fc813-ae88-467d-aebe-badd7c460c73
Publikováno v:
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
Biochimica et biophysica acta. Molecular cell research
Biochimica et biophysica acta. Molecular cell research
The developmentally indispensable Notch pathway exhibits a high grade of pleiotropism in its biological output. Emerging evidence supports the notion of post-translational modifications (PTMs) as a modus operandi controlling dynamic fine-tuning of No
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1577455b63ea5ba45c74e8c9239ad583