Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Christian Ansgar Hundahl"'
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76565 (2013)
BACKGROUND: Stroke is a major cause of death and severe disability, but effective treatments are limited. Neuroglobin, a neuronal heme-globin, has been advocated as a novel pharmacological target in combating stroke and neurodegenerative disorders ba
Externí odkaz:
https://doaj.org/article/56223bf414734722852d7e9687b10e10
Autor:
Christian Ansgar Hundahl, Betina Elfving, Heidi Kaastrup Müller, Anders Hay-Schmidt, Gregers Wegener
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63288 (2013)
BACKGROUND: Cytoglobin (Cygb) was discovered a decade ago as the fourth vertebrate heme-globin. The function of Cygb is still unknown, but accumulating evidence from in vitro studies point to a putative role in scavenging of reactive oxygen species a
Externí odkaz:
https://doaj.org/article/7614600627204db7a8cb5d5dacb8ed86
Autor:
Christian Ansgar Hundahl, Hendrik Luuk, Sten Ilmjärv, Birgitte Falktoft, Zindy Raida, Jonas Vikesaa, Lennart Friis-Hansen, Anders Hay-Schmidt
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28160 (2011)
Neuroglobin (Ngb), a neuron-specific globin that binds oxygen in vitro, has been proposed to play a key role in neuronal survival following hypoxic and ischemic insults in the brain. Here we address whether Ngb is required for neuronal survival follo
Externí odkaz:
https://doaj.org/article/dfec5d1840e846779625871225845814
Publikováno v:
Gotzsche, C R, Woldbye, D P D, Hundahl, C A & Hay-Schmidt, A 2022, ' Neuroglobin deficiency increases seizure susceptibility but does not affect basal behavior in mice ', Journal of Neuroscience Research, vol. 100, no. 10, pp. 1921-1932 . https://doi.org/10.1002/jnr.25105
Neuroglobin (Ngb) is found in the neurones of several different brain areas and is known to bind oxygen and other gaseous molecules and reactive oxygen species (ROS) in vitro, but it does not seem to act as a respiratory molecule for neurones. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da2a2beafed6634c27435303cdd26a4
https://curis.ku.dk/ws/files/317078286/Neuroglobin.pdf
https://curis.ku.dk/ws/files/317078286/Neuroglobin.pdf
Autor:
Christian Ansgar Hundahl, Kattri-Liis Eskla, Rando Porosk, Riin Reimets, Eero Vasar, Tanel Visnapuu, Hendrik Luuk
Publikováno v:
Free radical biologymedicine. 121
Mild hypothermia (32 °C) is routinely used in medical practice to alleviate hypoxic ischemic damage, however, the mechanisms that underlie its protective effects remain uncertain. Using a systems approach based on genome-wide expression screens, rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c7a1d21a3e696bd23c526f3aefbe31
https://pubmed.ncbi.nlm.nih.gov/29704622
https://pubmed.ncbi.nlm.nih.gov/29704622
Publikováno v:
Biomedical Reports. 2:780-786
Several previous studies have raised controversy over the functional role of neuroglobin (Ngb) in the retina. Certain studies indicate a significant impact of Ngb on retinal physiology, whereas others are conflicting. The present is an observational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8eca92a6a1f57219961e5588d08dd5c
https://doi.org/10.3892/br.2014.364
https://doi.org/10.3892/br.2014.364
Publikováno v:
Biochemical and Biophysical Research Communications. 425:100-106
Neuroglobin (Ngb), a neuronal specific oxygen binding heme-globin, reported to be expressed at high levels in most layers of the murine retina. Ngb's function is presently unknown, but based on its high expression level and oxygen binding capabilitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19c72ed0a39754e539e7e264d1da5e3
https://doi.org/10.1016/j.bbrc.2012.07.061
https://doi.org/10.1016/j.bbrc.2012.07.061
Publikováno v:
Biochemical and Biophysical Research Communications. 424:274-278
Cytoglobin, a new member of the mammalian heme-globin family has been shown to bind oxygen and to have cell protective properties in vitro. Cytoglobin is specifically expressed in a subpopulation of brain neurons. Based on hypoxia-induced up regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f51b2dddea2282874dcf735b2d1c4b
https://doi.org/10.1016/j.bbrc.2012.06.105
https://doi.org/10.1016/j.bbrc.2012.06.105
Autor:
Alexander Fleischmann, Jens Hannibal, Troy W. Margrie, Bruno Pichler, Kamilla Angelo, Christian Ansgar Hundahl, Ede A. Rancz, Diogo O. Pimentel
Publikováno v:
Nature
One defining characteristic of the mammalian brain is its neuronal diversity1. For a given region, substructure or layer and even cell type2, variability in neuronal morphology and connectivity2-5 persists. While it is well established that such cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb50dfa80ec0a13083aa70c4e5fc9e7
http://europepmc.org/articles/PMC3442227
http://europepmc.org/articles/PMC3442227
Autor:
Jan Fahrenkrug, Christian Ansgar Hundahl, Jens Hannibal, Jens F. Rehfeld, Lennart Friis-Hansen
Publikováno v:
European Journal of Neuroscience. 32:1006-1017
The suprachiasmatic nucleus (SCN) is the principal pacemaker driving circadian rhythms of physiology and behaviour. Neurons within the SCN express both classical and neuropeptide transmitters which regulate clock functions. Cholecyctokinin (CCK) is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34428af595e01f9bf8c81ce0d13fdc11
https://doi.org/10.1111/j.1460-9568.2010.07385.x
https://doi.org/10.1111/j.1460-9568.2010.07385.x