Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Christian Andrew Hassig"'
Autor:
Triparna Sen, Youhong Fan, Snezana Milutinovic, Lixia Diao, Christian Andrew Hassig, Ryan J. Hansen, Jing Wang, Robert J. Cardnell, Lauren Averett Byers, Bryan Strouse, Michael P Hedrick
Publikováno v:
Cancer Immunology Research. 8:B15-B15
Background: Small-cell lung cancer (SCLC) is the most aggressive form of lung cancer. Despite the recent success of immunotherapy in other indications, only a minority of SCLC patients respond to immune checkpoint blockade (ICB) targeting programmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f137a956849af2301b8e17c477c7b248
https://doi.org/10.1158/2326-6074.tumimm18-b15
https://doi.org/10.1158/2326-6074.tumimm18-b15
Autor:
David J. Newman, Daniela B. Divlianska, Amy E. Wright, Christine E. Salomon, Sylvia Kim, Paul Kung, Barry R. O'Keefe, Susan G. Brown, Thomas R. Hoye, Mehrak Kiankarimi, Dayong Zhai, John C. Reed, Michael A. Walters, Paul Diaz, Shana Morshedian, Andrew R. Michel, Subhashree Francis, Christian Andrew Hassig, Kate Welsh, Harneet Kaur, Fu Yue Zeng, Gunda I. Georg, Beeraiah Baire, Gregory P. Roth, Ying Su, Yudi Rusman
Publikováno v:
SLAS Discovery. 19:1201-1211
Antiapoptotic Bcl-2 family proteins are validated cancer targets composed of six related proteins. From a drug discovery perspective, these are challenging targets that exert their cellular functions through protein-protein interactions (PPIs). Altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccdeeb6b0346716bae36798d5495c2e
https://doi.org/10.1177/1087057114536227
https://doi.org/10.1177/1087057114536227
Autor:
Christian Andrew Hassig, Anthony B. Pinkerton, Michael P Hedrick, Sicong Li, Doris Niewolik, Howard H.Y. Chang, Michael R. Lieber, Klaus Schwarz
ARTEMIS is a member of the metallo-β-lactamase protein family. ARTEMIS has endonuclease activity at DNA hairpins and at 5′- and 3′-DNA overhangs of duplex DNA, and this endonucleolytic activity is dependent upon DNA-PKcs. There has been uncertai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468d2539e77cdd38bb70f9288ad61fa3
https://europepmc.org/articles/PMC3953294/
https://europepmc.org/articles/PMC3953294/
Inhibition of Melanoma Growth by Small Molecules that Promote the Mitochondrial Localization of ATF2
Autor:
Christian Andrew Hassig, Susanne Heynen-Genel, Loribelle Milan, Ze'ev Ronai, Tal Varsano, Eric Lau, Marine Garrido, Yongmei Feng
Purpose: Effective therapy for malignant melanoma, the leading cause of death from skin cancer, remains an area of significant unmet need in oncology. The elevated expression of PKCϵ in advanced metastatic melanoma results in the increased phosphory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4baa42c7805fbb64e9bec42907116f
https://europepmc.org/articles/PMC3690798/
https://europepmc.org/articles/PMC3690798/