Identification of VEGFR2 as the Histatin-1 receptor in endothelial cells

Autor: Carlos Mateluna, Pedro Torres, Marcelo Rodriguez–Peña, Patricio Silva, Douglas J. Matthies, Alfredo Criollo, Floris J. Bikker, Jan G.M. Bolscher, Christian A.M. Wilson, Gerald Zapata–Torres, Vicente A. Torres

Publikováno v: Biochemical Pharmacology, 201:115079, 1-14. Elsevier Inc.
Mateluna, C, Torres, P, Rodriguez–Peña, M, Silva, P, Matthies, D J, Criollo, A, Bikker, F J, Bolscher, J G M, Wilson, C A M, Zapata–Torres, G & Torres, V A 2022, ' Identification of VEGFR2 as the Histatin-1 receptor in endothelial cells ', Biochemical Pharmacology, vol. 201, 115079, pp. 1-14 . https://doi.org/10.1016/j.bcp.2022.115079

Histatin-1 is a salivary peptide with antimicrobial and wound healing promoting activities, which was previously shown to stimulate angiogenesis in vitro and in vivo via inducing endothelial cell migration. The mechanisms underlying the proangiogenic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce726894137734f4d4205f24bf1c94b0
https://research.vu.nl/en/publications/96bbf8e9-92c7-41c4-8fcb-dfff14a21c6e

Divalent metal cation requirements of phosphofructokinase-2 from E. coli. Evidence for a high affinity binding site for Mn2+

Autor: Jorge Babul, Andrés Caniuguir, Christian A.M. Wilson, Jaime Andrés Rivas-Pardo, Victoria Guixé

Publikováno v: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Artículos CONICYT
CONICYT Chile
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The reaction catalyzed by E. coli Pfk-2 presents a dual-cation requirement. In addition to that chelated by the nucleotide substrate, an activating cation is required to obtain full activity of the enzyme. Only Mn 2+ and Mg 2+ can fulfill this role b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fa27f346335cd29f3c1af38924da99
https://doi.org/10.1016/j.abb.2010.09.020

A Hybrid Tirf-Magnetic Tweezers Instrument for Studying Force-Induced Conformational Changes in Proteins

Autor: Christian A.M. Wilson, Carlos Bustamante, Samuel M. Leachman, Susan Marqusee, Bernardo Cervantes, Athena Ierokomos

Publikováno v: Biophysical Journal. 104(2)

Optical tweezers are a useful research tool for applying forces to single proteins and measuring the resulting changes in extension, but they can only observe conformational changes along the axis of force application and only if the accompanying cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4dec62fefa3746bfe58b1d2466fb1c

Measurement of glycogen synthase activity in crude extracts by CE

Autor: Christian A.M. Wilson, Ana Preller, M.A. Valenzuela, Tito Ureta

Publikováno v: Electrophoresis. 28(16)

Glycogen synthase catalyzes the incorporation of UDP-glucose into glycogen. The activity of the enzyme is usually measured either by a spectrophotometric method or by a radioassay. The first one is not suitable because of the difficulties regarding t

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https://pubmed.ncbi.nlm.nih.gov/17702064

Expanded Monomeric Intermediate upon Cold and Heat Unfolding of Phosphofructokinase-2 from Escherichia coli

Autor: Christian A.M. Wilson, Mauricio Baez, César A. Ramírez-Sarmiento, Victoria Guixé, Jorge Babul

Publikováno v: BIOPHYSICAL JOURNAL
Artículos CONICYT
CONICYT Chile
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Folding studies have been focused mainly on small, single-domain proteins or isolated single domains of larger proteins. However, most of the proteins present in biological systems are composed of multiple domains, and to date, the principles that un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d37a009366377bfa903022536872c21