Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Christian A. Rees"'
Autor:
Maximilian Diehn, David Botstein, Patrick O. Brown, Tina Hernandez-Boussard, Gavin Sherlock, Gail Binkley, Heng Jin, Christian A. Rees, Ash A. Alizadeh, J. Michael Cherry, John C. Matese
Publikováno v:
Nucleic Acids Research. 31:219-223
The explosion in the number of functional genomic datasets generated with tools such as DNA microarrays has created a critical need for resources that facilitate the interpretation of large-scale biological data. SOURCE is a web-based database that b
Publikováno v:
BMC Bioinformatics, Vol 5, Iss 1, p 141 (2004)
BMC Bioinformatics
BMC Bioinformatics
Background When publishing large-scale microarray datasets, it is of great value to create supplemental websites where either the full data, or selected subsets corresponding to figures within the paper, can be browsed. We set out to create a CGI app
Autor:
David Botstein, Per Eystein Lønning, Christian A. Rees, Stefanie S. Jeffrey, Therese Sørlie, Patrick O. Brown, Jonathan R. Pollack, Robert Tibshirani, Anne Lise Børresen-Dale, Charles M. Perou
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 99(20)
Genomic DNA copy number alterations are key genetic events in the development and progression of human cancers. Here we report a genome-wide microarray comparative genomic hybridization (array CGH) analysis of DNA copy number variation in a series of
Autor:
Matt van de Rijn, Cheryl A. Williams, Hilde Johnsen, Anne Lise Børresen-Dale, Alexander Pergamenschikov, Douglas T. Ross, Shirley Zhu, Christian A. Rees, Patrick O. Brown, David Botstein, Therese Sørlie, Michael B. Eisen, Jonathan R. Pollack, Stefanie S. Jeffrey, Lars A. Akslen, Charles M. Perou, Per Eystein Lønning, Øystein Fluge
Publikováno v:
Nature. 406(6797)
Human breast tumours are diverse in their natural history and in their responsiveness to treatments1. Variation in transcriptional programs accounts for much of the biological diversity of human cells and tumours. In each cell, signal transduction an
Autor:
Douglas T. Ross, Alexander Pergamenschikov, Uwe Scherf, Christian A. Rees, Jeffrey C. Lee, Dari Shalon, David Botstein, Vishwanath R. Iyer, Stefanie S. Jeffrey, Charles M. Perou, Matt van de Rijn, John N. Weinstein, Michael B. Eisen, Deval A. Lashkari, Mark Waltham, Patrick O. Brown, Paul T. Spellman, Timothy G. Myers
Publikováno v:
Nature genetics. 24(3)
We used cDNA microarrays to explore the variation in expression of approximately 8,000 unique genes among the 60 cell lines used in the National Cancer Institute's screen for anti-cancer drugs. Classification of the cell lines based solely on the obs
Autor:
David Botstein, Shirley Zhu, Patrick O. Brown, Douglas T. Ross, Cheryl F. Williams, Matt van de Rijn, Stefanie S. Jeffrey, Deval A. Lashkari, Jeffrey C. Lee, Charles M. Perou, Alexander Pergamenschikov, Christian A. Rees, Michael B. Eisen, Dari Shalon
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(16)
cDNA microarrays and a clustering algorithm were used to identify patterns of gene expression in human mammary epithelial cells growing in culture and in primary human breast tumors. Clusters of coexpressed genes identified through manipulations of m
Publikováno v:
BMC Bioinformatics. 5:141
When publishing large-scale microarray datasets, it is of great value to create supplemental websites where either the full data, or selected subsets corresponding to figures within the paper, can be browsed. We set out to create a CGI application co
Autor:
Tina Hernandez-Boussard, Catherine A. Ball, Christian A. Rees, Ihab A. B. Awad, Gavin Sherlock
Publikováno v:
BMC Bioinformatics. 5:151
Microarray-based comparative genome hybridization experiments generate data that can be mapped onto the genome. These data are interpreted more easily when represented graphically in a genomic context. We have developed Caryoscope, which is an open s
Autor:
Allen T. Christian, Johann Y Lin, Patrick O. Brown, Mark H. Ginsberg, Fan-Li Chou, Joel S. Bedford, Christian A. Rees, Jonathan R. Pollack
Publikováno v:
Genome Biology. 3:research0026.1
Somatic cell mutants can be informative in the analysis of a wide variety of cellular processes. The use of map-based positional cloning strategies in somatic cell hybrids to analyze genes responsible for recessive mutant phenotypes is often tedious,
Autor:
Anne-lise Borresen-Dale, Ash A. Alizadeh, David Botstein, Michael B. Eise, Per Eystein Lønning, Matt van de Rijn, Cheryl F. Williams, Jonathan R. Pollack, T Sørlie, Charles M. Perou, Stefanie S. Jeffrey, Alexander Pergamenschikov, Christian A. Rees, Hilde Johnsen, Patrick O. Brown, Stephanie Geisler, Turid Aas
Publikováno v:
Nature Genetics. 23:69-69