Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Christian Neusüß"'
Autor:
Patrick Schlossbauer, Lukas Naumann, Florian Klingler, Madina Burkhart, René Handrick, Kathrin Korff, Christian Neusüß, Kerstin Otte, Friedemann Hesse
Publikováno v:
Engineering in Life Sciences, Vol 24, Iss 6, Pp n/a-n/a (2024)
Abstract Cell engineering strategies typically rely on energy‐consuming overexpression of genes or radical gene‐knock out. Both strategies are not particularly convenient for the generation of slightly modulated phenotypes, as needed in biosimila
Externí odkaz:
https://doaj.org/article/8dcdbbb84fc94f5d93f3c2f682b96283
Publikováno v:
Analytical Chemistry. 95:4059-4066
Publikováno v:
Capillary Electrophoresis‐Mass Spectrometry for Proteomics and Metabolomics. :1-33
Publikováno v:
ELECTROPHORESIS. 44:246-267
The online coupling of microchip electrophoresis (ME) as a fast, highly efficient, and low-cost miniaturized separation technique to mass spectrometry (MS) as an information-rich and sensitive characterization technique results in ME–MS an attracti
Autor:
Lukas Naumann, Adrian Haun, Alisa Höchsmann, Michael Mohr, Martin Novák, Dirk Flottmann, Christian Neusüß
Publikováno v:
Analytical and Bioanalytical Chemistry.
In mass spectrometry (MS)-based metabolomics, there is a great need to combine different analytical separation techniques to cover metabolites of different polarities and apply appropriate multi-platform data processing. Here, we introduce AriumMS (a
Autor:
Rebecca Wiesner, Holger Zagst, Wenkui Lan, Stewart Bigelow, Peter Holper, Göran Hübner, Leila Josefsson, Claire Lancaster, Lili Lo, Christopher Lößner, Huixin Lu, Christian Neusüß, Carolin Rüttiger, Johannes Schlecht, Philipp Schürrle, Alexander Selsam, Debbie van der Burg, Shao‐Chun Wang, Yunxiao Zhu, Hermann Wätzig, Cari Sänger‐van de Griend
Publikováno v:
ELECTROPHORESIS.
Native mass spectrometry is a rapidly emerging technique for fast and sensitive structural analysis of protein constructs, maintaining the protein higher order structure. The coupling with electromigrative separation techniques under native condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d2845f80f616be55a21bad2245e1224
https://doi.org/10.22541/au.167872031.13574357/v1
https://doi.org/10.22541/au.167872031.13574357/v1
Autor:
Lukas Naumann, Patrick Schlossbauer, Florian Klingler, Friedemann Hesse, Kerstin Otte, Christian Neusüß
Publikováno v:
Journal of Separation Science. 45:2034-2044
The analysis of monoclonal antibodies glycosylation is a crucial quality control attribute of biopharmaceutical drugs. High throughput screening approaches for antibody glycoform analysis are required in various stages of process optimization. Here,
Autor:
Alexander Stolz, Christian Neusüß
Publikováno v:
Analytical and Bioanalytical Chemistry
The ever-increasing complexity of biological samples to be analysed by mass spectrometry has led to the necessity of sophisticated separation techniques, including multidimensional separation. Despite a high degree of orthogonality, the coupling of l
Publikováno v:
ElectrophoresisREFERENCES.
Imaged capillary isoelectric focusing (iCIEF) has emerged as an important technique for therapeutic monoclonal antibody (mAb) charge heterogeneity analysis in the biopharmaceutical context, providing imaged detection and quantitation by UV without a