Zobrazeno 1 - 10
of 516
pro vyhledávání: '"Christian Marth"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Somatic mutations within the exonuclease proofreading domain (EDM) of the DNA polymerase Pol ϵ (POLE) gene are increasingly being discovered in ovarian, colorectal, urological, and, especially, endometrial carcinoma (EC), where these are found in up
Externí odkaz:
https://doaj.org/article/51304ad18bba4291a5647a9faba1733a
Autor:
Christine Brunner, Miriam Emmelheinz, Daniel Egle, Magdalena Ritter, Katharina Leitner, Verena Wieser, Carmen Albertini, Samira Abdel Azim, Irene Mutz-Dehbalaie, Johanna Kögl, Christian Marth
Publikováno v:
Breast, Vol 76, Iss , Pp 103763- (2024)
Objective: This study aimed to demonstrate the superiority of cryocompression over cryotherapy alone in the prevention of chemotherapy-induced peripheral neuropathy (CIPN) grade 2 or above. Methods: This prospective randomized study was conducted bet
Externí odkaz:
https://doaj.org/article/c24f27f4f7e747d2af650b46e7f4245e
Autor:
Christian Marth, Vimalanand S Prabhu, Jingchuan Zhang, Sneha S Kelkar, Véronique Grall, Nicola Miles, Yao Qiao
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Objective To evaluate real-world treatment patterns and clinical outcomes in recurrent/advanced endometrial cancer patients who progressed following prior systemic therapy in clinical practice in Europe.Design Endometrial Cancer Health Outcomes-Europ
Externí odkaz:
https://doaj.org/article/5f18f1b66ce94919be4398f42a86529f
Autor:
Christine Brunner, Miriam Emmelheinz, Ricarda Kofler, Samira Abdel Azim, Marlene Lehmann, Verena Wieser, Magdalena Ritter, Anne Oberguggenberger, Christian Marth, Daniel Egle
Publikováno v:
Breast, Vol 64, Iss , Pp 50-55 (2022)
Externí odkaz:
https://doaj.org/article/29ac2deebb74400ca60e13fef532ce5a
Autor:
Pamela M. J. McLaughlin, Maximilian Klar, Tibor A. Zwimpfer, Gilles Dutilh, Marcus Vetter, Christian Marth, Andreas du Bois, Carmen Schade-Brittinger, Alexander Reuss, Claudine Bommer, Christian Kurzeder, Viola Heinzelmann-Schwarz
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background A high percentage of epithelial ovarian cancers (EOC) express the estrogen receptor (ER), which is an ideal target for endocrine therapy. Letrozole is a proven, potent aromatase inhibitor, extensively tested and used in the treatm
Externí odkaz:
https://doaj.org/article/a3bafe4e516e4091bd8136116db1cd5d
Autor:
Nicole Heinzl, Katarzyna Koziel, Elisabeth Maritschnegg, Astrid Berger, Elisabeth Pechriggl, Heidi Fiegl, Alain G. Zeimet, Christian Marth, Robert Zeillinger, Nicole Concin
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The tumor suppressor protein p53 is mutated in half of all cancers and has been described to form amyloid-like structures, commonly known from key proteins in neurodegenerative diseases. Still, the clinical relevance of p53 aggregates remains largely
Externí odkaz:
https://doaj.org/article/3ce52af3f7894bba962ddcab3b06bac9
Autor:
Katharina Leitner, Irina Tsibulak, Verena Wieser, Katharina Knoll, Daniel Reimer, Christian Marth, Heidi Fiegl, Alain G. Zeimet
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract SMARCA4 and EZH2 are two functional key players of their respective antagonizing chromatin remodeling complexes SWI/SNF and PRC2. EZH2 inhibitory drugs may abrogate pro-oncogenic features of PRC2 and turn the balance to cell differentiation
Externí odkaz:
https://doaj.org/article/c0f898d9b817455c806a36660ea6347a
Autor:
Guenther G. Steger, Daniel Egle, Rupert Bartsch, Georg Pfeiler, Edgar Petru, Richard Greil, Ruth Helfgott, Christian Marth, Leopold Öhler, Michael Hubalek, Alois Lang, Christoph Tinchon, Ferdinand Haslbauer, Andreas Redl, Karin Hock, Mathias Hennebelle, Bernhard Mraz, Michael Gnant
Publikováno v:
Breast, Vol 50, Iss , Pp 64-70 (2020)
Background: STEPAUT, an Austrian non-interventional study, evaluated the safety and efficacy of everolimus plus exemestane in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2−) advanced breast c
Externí odkaz:
https://doaj.org/article/7f2b64fd23e24290aaa6209341e7250f
Autor:
Verena Wieser, Irina Tsibulak, Daniel Uwe Reimer, Alain Gustave Zeimet, Heidelinde Fiegl, Hubert Hackl, Christian Marth
Publikováno v:
Gynecologic Oncology. 170:290-299
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e4ee04c0bbd73a7dc8c63bfd715dcbe
https://doi.org/10.1016/j.ygyno.2023.01.034
https://doi.org/10.1016/j.ygyno.2023.01.034
Autor:
Isabelle Ray-Coquard, Ioana Braicu, Regina Berger, Sven Mahner, Jalid Sehouli, Eric Pujade-Lauraine, Philippe Alexandre Cassier, Ute Martha Moll, Hanno Ulmer, Karin Leunen, Alain Gustave Zeimet, Christian Marth, Ignace Vergote, Nicole Concin
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background: Stabilized mutant p53 protein (mutp53) is a novel target in epithelial ovarian cancer. Due to aberrant conformation, mutp53 proteins depend on folding support by the Hsp90 chaperone. Hsp90 blockade induces degradation of mutp53, resulting
Externí odkaz:
https://doaj.org/article/8601cb9f6b384df886c2d55dca630015