Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christian, de Caestecker"'
Autor:
Janene Pierce, Andrew J. Murphy, Alexis Panzer, Christian de Caestecker, Gregory D. Ayers, David Neblett, Kenyi Saito-Diaz, Mark de Caestecker, Harold N. Lovvorn, III
Publikováno v:
Translational Oncology, Vol 7, Iss 6, Pp 800-811 (2014)
Wilms tumor (WT) blastema retains gene expression profiles characteristic of the multipotent nephron progenitor pool, or cap mesenchyme (CM), in the developing kidney. As a result, WT blastema and the CM are believed to represent contextual analogues
Externí odkaz:
https://doaj.org/article/2ecb52cfd93c45468736f3c586d7f5ba
Autor:
Andrew J. Murphy, Christian de Caestecker, Janene Pierce, Scott C. Boyle, Gregory D. Ayers, Zhiguo Zhao, Jaime M. Libes, Hernan Correa, Teagan Walter, Stacey S. Huppert, Alan O. Perantoni, Mark P. de Caestecker, Harold N. Lovvorn, III
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 12, Pp 1153-1163 (2012)
Hepatoblastoma, the most common pediatric liver cancer, consists of epithelial mixed embryonal/fetal (EMEF) and pure fetal histologic subtypes, with the latter exhibiting a more favorable prognosis. Few embryonal histology markers that yield insight
Externí odkaz:
https://doaj.org/article/0ca02d00ae4f45f28a4e012902e98800
Autor:
Jovanka Gusman, Russell C. Dale, Renzo Guerrini, Gladys Ho, Christian de Caestecker, Annalisa Vetro, Minal Menezes, Syed M. Ahmed, Felicity Collins, John Christodoulou, Daniella H Hock, Tiziana Pisano, Marcel E. Dinger, Mark J. Cowley, Seana Glover, Sean Massey, Nicole J Van Bergen, Ian G. Macara, David A. Stroud
Publikováno v:
The Journal of Experimental Medicine
Patients with severe developmental delay, dysmorphism, and brain abnormalities were identified as having pathogenic mutations in EXOC2, a critical component of the exocyst complex involved in vesicle trafficking, which caused secretory vesicle transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3ca0bb91222fe180fe40a471f65efb
https://doi.org/10.1084/jem.20192040
https://doi.org/10.1084/jem.20192040
Autor:
Shunsuke Tanigawa, David Neblett, Thomas L. Carroll, Amrita Das, Jaime Libes, Jeffrey S. Dome, Christian de Caestecker, Harold N. Lovvorn, Janene Pierce, Alan O. Perantoni, James R. Anderson, Andrew J. Murphy, Mark P. de Caestecker
Publikováno v:
Pediatric Blood & Cancer. 61:198-205
Background The Yes-associated-protein-1 (YAP1) is a novel, direct regulator of stem cell genes both in development and cancer. FAT4 is an upstream regulator that induces YAP1 cytosolic sequestering by phosphorylation (p-Ser 127) and therefore inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baf65730c1a810121b32d2718c7c7090
https://doi.org/10.1002/pbc.24788
https://doi.org/10.1002/pbc.24788
Autor:
Hernan Correa, Harold N. Lovvorn, Mark W. Newton, Erin H. Seeley, Andrew J. Murphy, Janene Pierce, Jason R. Axt, Richard M. Caprioli, Christian de Caestecker, Mark P. de Caestecker
Publikováno v:
International Journal of Cancer. 131:E983-E994
Sub-Saharan African children have an increased incidence of Wilms' tumor (WT) and experience alarmingly poor outcomes. Although these outcomes are largely due to inadequate therapy, we hypothesized that WT from this region exhibits features of biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf5ee110107f60f9da59973b7baeef6
https://doi.org/10.1002/ijc.27544
https://doi.org/10.1002/ijc.27544
Autor:
Marie-Claude Theberge, Paul A. Voziyan, Nataliya I. Skrypnyk, Haichun Yang, Billy G. Hudson, Raymond C. Harris, Mathieu Drouin, Mark P. de Caestecker, Christian de Caestecker
Publikováno v:
American journal of physiology. Renal physiology. 311(2)
Acute kidney injury (AKI) is a common and independent risk factor for death and chronic kidney disease (CKD). Despite promising preclinical data, there is no evidence that antioxidants reduce the severity of injury, increase recovery, or prevent CKD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8da4d9570d0fa2163052614a60aa11
https://pubmed.ncbi.nlm.nih.gov/27194713
https://pubmed.ncbi.nlm.nih.gov/27194713
Autor:
Andrew J. Murphy, Janene Pierce, Christian de Caestecker, Gregory D. Ayers, Alex Zhao, Hernan Correa, Jonathan R. Krebs, Vincente Kenyi Saito-Diaz, Ethan Lee, Alan O. Perantoni, Mark P. de Caestecker, Harold N. Lovvorn
Publikováno v:
Oncotarget
Wilms tumor (WT) is the most common childhood kidney cancer and retains gene expression profiles reminiscent of the embryonic kidney. We have shown previously that CITED1, a transcriptional regulator that labels the self-renewing, multipotent nephron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487d33ec1940b2e8c24d41b165b5ad78
https://pubmed.ncbi.nlm.nih.gov/24481423
https://pubmed.ncbi.nlm.nih.gov/24481423
Autor:
Andrew J, Murphy, Janene, Pierce, Christian, de Caestecker, Jaime, Libes, David, Neblett, Mark, de Caestecker, Alan O, Perantoni, Shunsuke, Tanigawa, James R, Anderson, Jeffrey S, Dome, Amrita, Das, Thomas J, Carroll, Harold N, Lovvorn
Publikováno v:
Pediatric bloodcancer. 61(2)
The Yes-associated-protein-1 (YAP1) is a novel, direct regulator of stem cell genes both in development and cancer. FAT4 is an upstream regulator that induces YAP1 cytosolic sequestering by phosphorylation (p-Ser 127) and therefore inhibits YAP1-depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fcdd62da991d79f36c0052ac2d1329e
https://pubmed.ncbi.nlm.nih.gov/24376227
https://pubmed.ncbi.nlm.nih.gov/24376227
Autor:
Mark P. de Caestecker, Christian de Caestecker, Andrew J. Murphy, Harold N. Lovvorn, Janene Pierce, Chase J. Taylor, James R. Anderson, Alan O. Perantoni
Publikováno v:
Journal of pediatric surgery. 47(6)
Purpose SIX2 and CITED1 are transcriptional regulators that specify self-renewing nephronic progenitor cells of the embryonic kidney. We hypothesized that SIX2, which promotes and maintains this stem cell population, and CITED1 remain active in Wilms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152c440e84d0ad5c84ce39d2a45ab3fc
https://pubmed.ncbi.nlm.nih.gov/22703800
https://pubmed.ncbi.nlm.nih.gov/22703800
Autor:
Alan O. Perantoni, Christian de Caestecker, Andrew J. Murphy, Harold N. Lovvorn, Janene Pierce, Mark P. de Caestecker
Publikováno v:
Journal of the American College of Surgeons. 215:S78-S79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::265d4e31f0ebd89132c903d465ad970b
https://doi.org/10.1016/j.jamcollsurg.2012.06.216
https://doi.org/10.1016/j.jamcollsurg.2012.06.216